It has been a year since my last update on the prospective MSK-IMPACT/ACCESS sequencing cohort, now >120,000 tumor/cfDNA samples analyzed. Thanks to the patients, docs, nurses, techs, data scientists who have contributed. So where are we going next:
@bradloncar continues to run one of the best platforms for anyone to learn more about what's happening in the world of making new medicines (i.e. biotech!). Be sure to check out this chat with our CEO, @gline!
@rosslevinemd ππ This tweet contains two of my hall of fame physician scientist role models leading the way for all of us seeking to develop medicines for patients who need them!
This past weekend I had the *extreme* pleasure of reuniting with my @LoweLabMSKCC colleagues to share science, stories, smiles and laughter. The 4 years I spent in Scottβs lab continue to motivate me to work hard, do rigorous scienceβ¦.. and HAVE FUN! Thank you Scott!
What an incredible Reunion! It was wonderful to see all former lab members who traveled to NYC from all over the world & to experience the joy that we all shared in getting together. THANK YOU & stay in touch! #LoweLab25
βWeβre incredibly honored to receive this recognition. Roivant has always prided itself not only on our innovative business model but also on our commitment to fostering a culture that challenges convention and drives transformative change in the #biopharma industry,β@gline
The founder and former CEO of Vertex Pharmaceuticals, Joshua Boger, was once asked: "What does it take to be a good leader in a pharmaceutical company?"
Boger said, "Pharmaceutical discovery and development is the most complicated activity that humans do.
Going to Mars is easy, going to Mars is engineering! I mean, I'm not an engineer but if you give me a hundred billion dollars, I guarantee you I can put you on Mars. There's nothing stopping me except organisational momentum and money.
But if you give me a hundred billion dollars and say, in five years or ten years you have to cure Alzheimer's disease... I'll say... I'll give it a go but I have no idea whether I could do it!
Drug discovery and development is just an insanely complicated activity to do that you need to keep teams of people together for a very long time.
And this is what distinguishes it from most of the high-tech, ie. I have a high-tech idea, I should be shipping it in 18 months. If I have a pharmaceutical idea I may be shipping it in 18 years!
So I need to keep a team of people together on the discovery and development side for 12 to 15 years on average.
The most important thing is understanding team dynamics and the difference in personalities that are necessary to build a team and hold it together. To do that, you the leader have to be incredibly passionate about what you're trying to do. It's a combination of empathy and passion...
And you have to lead by example. Very often I was the last person to cut the lights out at midnight or 1 am. And it's not just the number of hours... the people who report to you can see you, and they can tell whether or not you're thinking about the mission all the time..."