Linus Williams, MD PhD

IM Chief Resident at Lahey Clinic | hopeful cardiologist interested in heart failure | PhD in cardiac transplant immunology | mouse surgeon | rock climber

[Sourbha Satish Dani, MD, MSc, FACC, FASE @SaurabhSDani]

Masterclass on Genetic Dilated Cardiomyopathy by superb @noshreza @bethisraellahey @LaheyResearch @LaheyHospital today! Fabulous talk on how #GeneFirst approach is valuable in caring for patients with DCM!

[Linus Williams, MD PhD @LCMWilliams2436]

Such an important thread and thank you for writing it Dr. Dani! Lies, damned lies, and statistics....

[Sourbha Satish Dani, MD, MSc, FACC, FASE @SaurabhSDani]

The Hook
Cardiology trials keep telling you "20% risk reduction."
But what if that same trial meant:
→ 1 in 50 patients helped (NNT 50)
→ 49 of 50 got zero benefit
Welcome to the greatest trick in clinical trials: Relative Risk vs. Absolute Risk. A thread 🧵👇

[Linus Williams, MD PhD @LCMWilliams2436]

@SaurabhSDani I am also gardening and growing Garlic! This will be my F1 generation from a clove I got from wegmans. Nothing like fresh garlic from the garden; I think I will harvest mine next week. Congratulations!

[Linus Williams, MD PhD @LCMWilliams2436]

help reduce the number of these hospitalizations. We must remember that quality of life is best affected in the outpatient setting and that we are no less clinicians for doing so. Thank you @SaurabhSDani for inviting this excellent speaker.

[Linus Williams, MD PhD @LCMWilliams2436]

Excellent talk by @dranulala on the role of the heart function (not failure) specialist, who really should be a generalist's generalist, since everything is heart function. Human health is intervention x time-based and I feel we need to be taking better care of our patients...

[Linus Williams, MD PhD @LCMWilliams2436]

...who are out living their lives and at risk for declines in heart function. This is not to say that patients presenting to the hospital in florid heart failure should not receive attention, but that we really need to be focusing on prevention in the outpatient setting to...

[Linus Williams, MD PhD @LCMWilliams2436]

Amazing talk this morning by the astounding Dr. @ChetRihal. I love medical history and I do believe we need to examine everything we do critically. Placebo effect, animal models, and even pathophysiological analysis can all lead us astray in our medical interventions.

[Sourbha Satish Dani, MD, MSc, FACC, FASE @SaurabhSDani]

Lipoprotein(a) and cardiovascular disease - The Lancet Fantastic Review on LpA, CVD and treatment options-#Premature CAD #SouthAsian https://t.co/x1I68jUWwM

[Linus Williams, MD PhD @LCMWilliams2436]

@MiscSusan I suppose context matters here. If said coworker had bought the apple watch and given it to the child that would be weird. But if they're just passing out apple watch 3's like candy at work and coworker doesn't particularly want or need it; not odd to give it to a kid who may.

[Linus Williams, MD PhD @LCMWilliams2436]

@SaurabhSDani So well-deserved! Enjoy the ME time!

[NEJM @NEJM]

Review Article: Guidance on Energy and Macronutrients across the Life Span https://t.co/Alr66l5ch8

Editorial: Nutrition in Medicine — A New Review Article Series https://t.co/jTRjOrElyY

[Linus Williams, MD PhD @LCMWilliams2436]

Great talk by @AllanLKleinMD1 about IL1 blockade in Recurrent pericarditis. Great advancement in a devastating condition.

[Linus Williams, MD PhD @LCMWilliams2436]

Blessed to be presenting a case of hypertrophic cardiomyopathy treated with MitraClip at @LaheyHospital at #ACC2024. Thank you to all my friends, family, and mentors who continue to support me during my training and research.🤩🤩🫶🫶

[Linus Williams, MD PhD @LCMWilliams2436]

@NephRodby Calciphylaxis?

[Gregg Fonarow MD @gcfmd]

Want to help prevent 7-8 million worsening HF events and cardiovascular deaths over the next 3 years?

Optimally implement SGLT2 inhibitors in eligible individuals with HF

At scale, Globally, Now

@JavedButler1 @_talhakhawaja @mvaduganathan @SJGreene_md

https://t.co/FsHelNUClu

[Sarju Ganatra, MD, FACC @SarjuGanatraMD]

Celebrating 100 Years of @LaheyHospital

Honored to be a part of the vision & journey of providing exceptional care to ALL in collaborative & innovative ways

There are many achievements & great future plans, but what remains constant is patient-centered care

[BiykemBozkurt @BiykemB]

#HFinductiontherapy is as important as cancer induction chemotherapy-
HF is as deadly as cancer is and HF GDMT improve outcomes. Initiate quadruple HF therapies as induction therapy and then consider add-on therapies as consolidation therapy in HFrEF. https://t.co/k3w94cnxmB

[Massachusetts ACC @ACCMass]

Cold and raining outside but nothing but smiles inside today for @ACCMass Annual Mtg! @md_harrington @omarsiddiqi @drmalissawood @SaurabhSDani @JJheart_doc @JamalRanaMD @MLHadleyDO

[Linus Williams, MD PhD @LCMWilliams2436]

Really great talk showing how biomarkers can be a great link from the acutely decompensated patient in the hospital to management in the outpatient setting where we can really make a difference in quality and quantity of life.

[Sonu Abraham, MD, FACC @SonuAbrahamMD]

Great talk by @JJheart_doc #ThekingofBiomarkers @ACCMass !

NT-proBNP
✅ Diagnosis
✅ Pre-discharge risk assessment
✅ Prognosis

Why is it elevated?
Acute HF - Volume overload
Chronic HF- Cardiac remodeling @drmalissawood @md_harrington @SaurabhSDani @omarsiddiqi

[Linus Williams, MD PhD @LCMWilliams2436]

Really great talk!

[Sonu Abraham, MD, FACC @SonuAbrahamMD]

Kicking of @ACCMass Annual meeting with ‘State if the Art Antithrombotic Therapies: Therapies for Coronary and Peripheral Atherosclerosis’ by Dr. Kelley Branch and Dr. Christian Ruff. @md_harrington @SaurabhSDani @JJheart_doc @JamalRanaMD @RohanParikhMD #ACCFIT @ACCinTouch