ChronoLabKoc

Circadian Clock and Biotechnology Research Group of @kocuniversity #circadianclock #biotechnology
PI: Prof. Dr. İ. Halil Kavaklı

[ChronoLabKoc @LabChrono]

@_ibrahimBaris @serefgulphd @KocSciences

[ChronoLabKoc @LabChrono]

Our recent research titled as "Functional characterization of the CRY2 circadian clock component variant p.Ser420Phe revealed a new degradation pathway for CRY2" where we identified the lysosomal-mediated degradation in CRY2 is now out @jbiolchem
https://t.co/HBeRxHlHql

[ChronoLabKoc @LabChrono]

Congratulations to Gizem Çağla @_ibrahimBaris @serefgulphd

#circadianclock #cry #autophagy #snp

[ChronoLabKoc @LabChrono]

Congratulations to Saliha, lab members and all collaborators
@serefgulphd @kubrakyel @zeynepgul @onurzca06090027 @NozluLab @AliCihanTaskin @mturkay @_ibrahimBaris @cihanaydinphd @alperokyar2

[ChronoLabKoc @LabChrono]

Our research, titled "TW68: A Cryptochromes Stabilizer, Regulates Fasting Blood Glucose Levels in Diabetic ob/ob and High Fat-Diet-Induced Obese Mice," has been published in the journal Biochemical Pharmacology.

https://t.co/5GhgSEEIPF

[ChronoLabKoc @LabChrono]

Our work titled as "Dynamic regulation of the serine loop by distant mutations reveals allostery in cryptochrome1" has been published at J. Biomolecular Structure and Dynamics

Congratulations to @onurzca06090027 @serefgulphd

https://t.co/f86JL5SmcS

[ChronoLabKoc @LabChrono]

Our work titled as "TW68, Cryptochromes stabilizer, regulates fasting blood glucose level in ob/ob and fat- induced diabetic mice" available @biorxivpreprint

https://t.co/xhxmpa80vt

#circadianclock #drugdesign #diabetes

[ChronoLabKoc @LabChrono]

Our book chapter has been published at "Advances in Protein Chemistry and Structural Biology" and where we summarize the relationship between circadian clock gene SNPs and diseases.

@_ibrahimBaris

https://t.co/ZWjaV2puQ3

[ChronoLabKoc @LabChrono]

Our collaborative paper with @alperokyar2 @kubrakyel titled "Diurnal Changes in Capecitabine Clock-Controlled Metabolism Enzymes Are Responsible for Its Pharmacokinetics in Male Mice" is published @JBR

https://t.co/cCiIFO9rXM

[ChronoLabKoc @LabChrono]

Yaşadığımız deprem felaketi dolayısıyla hayatını kaybedenlere Allah'tan rahmet, yakınlarına başsağlığı ve yaralılara acil şifalar diliyoruz.

[ChronoLabKoc @LabChrono]

@NatureComms'da yayınlanan çalışmamız ulusal basın tarafından haberleştirildi

https://t.co/LEFYVQtjsn

https://t.co/XRmKkWaI9l

https://t.co/Q02X6wfgHn

https://t.co/WvdFTHUE8z

https://t.co/3i2JTtCClv

[ChronoLabKoc @LabChrono]

It's a big loss in sleep biology and RIP

[Society for Research on Biological Rhythms @SRBR_Outreach]

The chronobiology and sleep fields have lost a wonderful colleague and friend to many. Steve Brown died from injuries sustained in an accident on Wednesday. Our thoughts are with his family, friends, lab and colleagues. RIP.

[ChronoLabKoc @LabChrono]

Barış's paper is published @jbiolchem joint afford with @KUYBIIGM

Paper describes the crystal structure of Vibrio cholerae (6-4) photolyase

@kuiscid @oergonul1

https://t.co/AtuagCuj14

[ChronoLabKoc @LabChrono]

@KuriousBlog 'da, @NatureComms 'da yayınlana son çalışmamızdan bahsedildi

https://t.co/aSXJGs9E7t

[ChronoLabKoc @LabChrono]

Our recent work @NatureComms has been highlighted @KuriousBlog

https://t.co/MzWxRCPtci

[ChronoLabKoc @LabChrono]

@NatureComms'da yayınlanan bu çalışmamız @Tubitak 1003 projesi kapsamında tamamlanmıştır. @ProfHasanMandal

@umransavasinan @KU_TTO

https://t.co/yEqexj8kGA

[ChronoLabKoc @LabChrono]

1) We are happy to share that our long lasting study has been published @NatureComms

We discovered a molecule (M47) that selectively binds and destabilizes CRY1 (core circadian clock protein).

https://t.co/kpDo8XQYKc

[ChronoLabKoc @LabChrono]

4) #circadianclock #cancer #CRY1 #smallmolecule #p53

[ChronoLabKoc @LabChrono]

@jbhclock