Weihl Lab

Conrad "Chris" Weihl lab | Washington University School of Medicine | Focusing on Protein Aggregation in Myopathies and Neurodegenerative diseases

[WashU Medicine Neurology @WashUNeurology]

There has never been a more exciting time to pursue a career in Neuromuscular Medicine! Our Neuromuscle fellowship offers trainees comprehensive didactics, a broad patient mix and foundational training in electrodiagnostics and nerve/muscle pathology.

https://t.co/VSqHIwqKn2

[Weihl Lab @LabWeihl]

Very nice excited this paper is out. It reveals the power of human genetics to understand molecular mechanism. Thanks to our collaborators. @WashUNeurology @TNRLab @CureVCPDisease

[Weihl Lab @LabWeihl]

An autosomal-dominant childhood-onset disorder associated with pathogenic variants in VCP: The American Journal of Human Genetics https://t.co/NEnpTLmocI

[WashU Medicine @washumedicine]

Congratulations to our three #WashUMed faculty members elected to the National Academy of Medicine: Michael S. Avidan, MBBCh, Sarah K. England, PhD, and Timothy Miller, MD, PhD. Learn more about their groundbreaking work here: https://t.co/FJb2cDq2o1

[CureCalpain3 @CureCalpain3]

C3 awarded a Travel Grant to Dr. Stephanie Hunn, Washington University School of Medicine. Dr. Hunn, a member of @LabWeihl, presented early longitudinal data from the GRASP-LGMD natural history study at #WMS2023 in Charleston, SC. Read more here:

https://t.co/FzwyKnauDg

[WashU Medicine Neurology @WashUNeurology]

Diagnosis of rare, genetic muscle disease improved by new approach
#WashUMed researchers have developed an approach that could help doctors distinguish between the many subtypes of limb girdle muscular dystrophy, a rare, genetic muscle disease.
@LabWeihl @WashUNeurosurg

[Weihl Lab @LabWeihl]

@MaliRamanLab @RichwithanA Very cool. I need one. Too.

[Malavika Raman @MaliRamanLab]

New pre-print from the lab! We performed quantitative proteomics in iPSC-derived motor neurons with p97 R155H mutation that causes ALS and MSP-1 and found lysophagy defects. https://t.co/AeauEhH6tw Congrats to @jay_clicks Thanks @jmaglab @LabWeihl @GygiLab

[Prof. Toshi Yokota PhD FCAHS @MD_Canada Res Chair @ToshifumiYokota]

Morpholino antisense oligos show potential in selectively reducing DNAJB6b isoform levels, correcting disease-related protein abnormalities according to Findlay et al: Promising progress in treating Limb Girdle Muscular Dystrophy D1 (LGMD D1). https://t.co/pCFEBUuMUC

[Teerin Liewluck, MD, FAAN, FANA @TLiewluck]

A patient from Charleston, SC gave me a list of his favorite restaurants when he learned that I will be attending the #WMS2023 in Charleston! I thought I should share this with @WorldMuscleSoc members.

[Weihl Lab @LabWeihl]

@YSPTSPS @DavidWSanders2 @JasonSynaptic I always teach this paper.

[Bede Portz @YSPTSPS]

@DavidWSanders2 @JasonSynaptic https://t.co/7vFfJ6ESFy indeed a very great paper but also where are all your suggestions ?

[NeurologyLive® @neurology_live]

Timothy Miller, MD, PhD, discussed tofersen’s impact on SOD1 protein and neurofilament light, as well as the need to initiate treatment as early as possible after #ALS diagnosis. @AmylyxPharma @WashUNeurology @NEALSConsortium #NEALS2022

Watch here: https://t.co/bQg5XSgXje

[Marco Savarese @MarcoSavareseIT]

Unsolved cases of fetuses or newborns with bone, heart and muscle anomalies? Check Titin #titin #medicalgenetics #research #neonatology #pediatrics @UddLab https://t.co/hLPwAVfoz7

[Nicholas Johnson @nickjohnson30]

GRASP LGMD meeting underway!

[Ellen Mowry @EllenMowryMD]

So proud of these amazing young physician scientists investigating how racism manifests in the clinic (Drs. Mysti Harrison and Jackie Bhattarai) and digging into more rare but significant neuroimmune disorder (@MariaIReyesMan1).

#teamwork
#ECTRIMS2022
@IntNatlWiMS

[christina applegate @1capplegate]

I have a very important ceremony coming up. This will be my first time out since diagnosed with MS. Walking sticks are now part of my new normal. Thank you @neowalksticks for these beauties. Stay tuned to see which ones make the cut for a week of stuff.

[Solve-RD @Solve_RD]

📢Conrad Weihl @LabWeihl @WUSTLmed, Ana Töpf & @VolkerWStraub @jwmdrc et al. just published their collaborative work in Acta Neuropathologica: Loss of function variants in DNAJB4 cause a #myopathy with early respiratory failure.
👉🏾 https://t.co/ocVQnU2nUP

@euro_nmd

[Weihl Lab @LabWeihl]

Loss of function variants in DNAJB4 cause a myopathy with early respiratory failure https://t.co/kZrSVEuZxo Just out.
great collaboration. @doctrue2 @BhadraAnkan @Gianina_Natoli @VolkerWStraub. Continually amazed how human genetics informs mechanism.

[Gisele Bonne @BonneGisele]

Young Myologist of the Year ⁦@WorldMuscleSoc⁩ #WMS2022 ⁦@SGorokhova⁩ ⁦@Myologie_MMG⁩ well deserved award congratulation !👍😄