Larry Pease, Ph.D.

Immunotherapy researcher at Mayo Clinic.

[Larry Pease, Ph.D. @LarryPeasePhD]

Thank you for a terrific chat. Its always good to help patients understand what is happening relevant to their care. #cimchat

[Larry Pease, Ph.D. @LarryPeasePhD]

A8 Again, a comprehensive care approach is critical. Patients so explore the complete spectrum of options. #cimchat

[Larry Pease, Ph.D. @LarryPeasePhD]

@SharonTheimer Richard Vile is the lead investigator on that approach #cimchat

[Larry Pease, Ph.D. @LarryPeasePhD]

@SharonTheimer Another approach used at Mayo is to hitch hike immune stimulants on viruses, targeting virus to the cancer #cimchat

[Larry Pease, Ph.D. @LarryPeasePhD]

@SharonTheimer There are several approaches being pursued along these lines. Antibody targeting of chemotherapy, for 1 (Markovic) #cimchat

[Larry Pease, Ph.D. @LarryPeasePhD]

Immune modulators which block immune check points could allow multiple cancer to be targeted at the same time #cimchat

[Larry Pease, Ph.D. @LarryPeasePhD]

A7 Cancers develop individually, but sometimes have common traits that can be targeted. Depends on why 1 has more than one cancer #cimchat

[Larry Pease, Ph.D. @LarryPeasePhD]

RT @MayoClinic A6: Researchers Develop Promising New Cancer Vaccine http://t.co/ADSk06kLRc #CIMchat

[Larry Pease, Ph.D. @LarryPeasePhD]

A6 Patients will differ with respect to developing side effects, so again an individualized approach will be important #cimchat

[Larry Pease, Ph.D. @LarryPeasePhD]

RT @SharonTheimer Patients interested in @MayoClinic trials can find them here; enter immunotherapy: http://t.co/h4BrngzfDx #cimchat

[Larry Pease, Ph.D. @LarryPeasePhD]

A5 Cancers are constantly changing and can evade immune mechanisms, so multiple or broad approaches are needed #cimchat

[Larry Pease, Ph.D. @LarryPeasePhD]

A5 Depends on whether the treatment is fully successful and whether good immunologic memory is a result. #cimchat

[Larry Pease, Ph.D. @LarryPeasePhD]

A4 Immunotherapy should be in administered in the context of comprehensive care #cimchat

[Larry Pease, Ph.D. @LarryPeasePhD]

A4 Investigators at Mayo Clinic are investigating this question (Drs Cohen and Markovic and colleagues) with some success #cimchat

[Larry Pease, Ph.D. @LarryPeasePhD]

A3 That is why individualized approaches being developed are critical to CI #cimchat

[Larry Pease, Ph.D. @LarryPeasePhD]

A3 Different kinds of cancers interface distinctively with the immune system. Similar cancers in different people can differ too #cimchat

[Larry Pease, Ph.D. @LarryPeasePhD]

A2 Immunity against cancer is often compromised by natural process of preventing autoimmunity and evasion of immunity by cancers #cimchat

[Larry Pease, Ph.D. @LarryPeasePhD]

A1 That is why it so important to understand how the immune system works, allowing immunity to be directed against cancer #cimchat

[Larry Pease, Ph.D. @LarryPeasePhD]

A1 CI uses many of the same cells we use to fight bacteria and viruses, but in somewhat different ways #cimchat

[Larry Pease, Ph.D. @LarryPeasePhD]

Hi! This is Larry Pease. I am a program leader for the cancer Immunology/Immunotherapy Program of the Mayo Cancer Center #cimchat