Legible

Making biotech more legible. Hosted by @shmkdbr

[Dr. Shelby @shelbynewsad]

@shmkdbr and I discuss the edges of biotech from DeSci to human evidence to where biotech is intersecting with culture with the emergence of looksmaxxing.

[Legible @LegibleBio]

I’ve long admired Shelby's thesis work in publicly sharing how biotech could unfold over the next decade.

We talk about everything from decentralized clinical trials to incumbent vs startup advantages in biotech. Hope you enjoy!

YouTube: https://t.co/SsNOTBQIkH

[Legible @LegibleBio]

Ep 5: Creative Destruction in Biotech with @shelbynewsad from @CompoundVC

Chapters
07:21 Platform vs Product
14:25 Creative Destruction in Biotech
23:54 Decentralized Science and Crypto
30:35 Careful with Gray Label Peptides
35:34 Accelerating Human Clinical Trials
45:36 The Role of Virtual Cell Models
50:01 The Evolution of Bio-Manufacturing
53:34 Consumer Biotech: The Next Frontier
58:51 Implications of Looksmaxxing

[Legible @LegibleBio]

Tomorrow with @shelbynewsad from @CompoundVC

We discuss consumer biotech, the problem with peptides, the implications of looksmaxxing, and much more

[Josie Zayner @josiezayner]

Being in SF this week has made me realize how underappreciated Biotech really is, two large events, Substack debate and Hamilton society have a Biotech focus yet very few founders and VCs I meet at all the parties and events working on/investing in Biotech. The technology is there and its in the zeitgeist and people care about it and it is obviously going to have a massive impact on our future

There is so much alpha in Biotech right now, especially compared to AI, on the founder and VC side its insane how its not being exploited

[Legible @LegibleBio]

@patricksmalone Agreed

[anabology @anabology]

Lfg - learn about Gilbert Ling & Aion here!

[Legible @LegibleBio]

https://t.co/BjVAowfISy

[Legible @LegibleBio]

Ep 4: Bioelectricity with @anabology

Rethinking cell membranes, origins of MRI, building Med Beds, and more

00:00 - Background and Bioelectricity
10:19 - Gilbert Ling
28:27 - Raymond Damidian
45:23 - What is Structured Water?
49:32 - Are Small Molecule Approaches a Dead End?
59:30 - Building Aion Biosciences in St Louis. MO
01:05:12 - Consciousness and Origin of Life
01:11:46 - Cosmetics Sidequest (https://t.co/eMF73U3VmY)

[Legible @LegibleBio]

Tomorrow with @anabology: bioelectricity, origins of MRI, and building Med Beds

[Legible @LegibleBio]

YouTube - https://t.co/9K9O1BUaMF
S*bstack - https://t.co/D5N2nVOGhx
Relevant links -
https://t.co/IdkO41Hfyk
https://t.co/zOowIJo9kv
https://t.co/rIm2Yx0ss3

[Legible @LegibleBio]

Ep 4: Bioelectricity with @anabology

Rethinking cell membranes, origins of MRI, building Med Beds, and more

00:00 - Background and Bioelectricity
10:19 - Gilbert Ling
28:27 - Raymond Damidian
45:23 - What is Structured Water?
49:32 - Are Small Molecule Approaches a Dead End?
59:30 - Building Aion Biosciences in St Louis. MO
01:05:12 - Consciousness and Origin of Life
01:11:46 - Cosmetics Sidequest (https://t.co/eMF73U3VmY)

[FREEDOM CAT @REALFREEDOMCAT]

Unc has still got it

Jake (@SynBio1) talks about the current state of biotech, and more importantly - where the hell AI really fits into biotech.

Interesting listen

[Legible @LegibleBio]

YouTube: https://t.co/Qgq6iNtOf3
Spotify: https://t.co/SGVXfZl83M
S*bstack: https://t.co/kbNXvgcIeo

[Legible @LegibleBio]

Ep 3: Read, Write, Grow with @SynBio1. We discuss the
100 year vision for synthetic biology, biotech's product problem, biomanufacturing, and more.

00:00 - Jake Wintermute’s Journey in Biotech
08:32 - The Vision for Synthetic Biology
15:59 - Bio-Manufacturing as a Gateway
18:48 - Platform vs Product Companies in Biotech
25:39 - The Role of AI in Drug Discovery
29:34 - Addressing Bottlenecks in Clinical Trials
31:25 - Communicating Synthetic Biology
38:35 - Consumer-Facing Biotechnologies

[Legible @LegibleBio]

YouTube: https://t.co/LKjsGk9758
Spotify: https://t.co/Img97M5diX
S*ubstack: https://t.co/1XnUqfdwN4

[Legible @LegibleBio]

Ep 2 with @OmicsOmicsBlog: Evolution of Biotech

We discuss lab automation, small molecules, life at @Ginkgo, and much more

00:00 - Evolution of Biotech: Past and Present
05:29 - Understanding Sequencing: Basics and Importance
10:07 - The Drug Development Process: Then and Now 17:18 - The Shift from Small Molecules to Biologics
22:11 - Chance and Unpredictability in Drug Discovery 26:35 - Sequencing Technologies: DNA, RNA, and Proteins
44:12 - Exciting Innovations in Sequencing
53:53 - Synthetic Biology and Ginkgo’s Vision
01:01:49 - Automation in Biotechnology
01:10:33 - Recommended Reads for Biotech Enthusiasts

[Legible @LegibleBio]

00:00 Circus to Genetics
05:14 Building a Sequencer
13:26 The Future of Sequencing: Decentralization and Accessibility
18:31 Challenges in Manufacturing and Scaling
21:21 Sequencing in Breweries
23:47 Building a Platform Company
29:54 Misunderstandings about Sequencing
35:09 What Does It Mean Go Fast in Biotech?
39:36 The Biotech Race: US vs. China
47:22 Family and Startups
54:33 The Role of Personality Types in Leadership

[Legible @LegibleBio]

Ep 1: Democratizing DNA sequencing with Ana Cornell

https://t.co/ZKi609v9Ie

[Legible @LegibleBio]

hello 🧬