Liang Liu

Postdoctoral scholar in @YongshengShi Lab @UCIrvine | @UCVirusResearch 🦠 | #RNA | #virology | Interested in mRNA 3’ processing in viral infection and disease

[Yongsheng Shi @YongshengShi]

Start the new year with a new publication! Led by the talented postdoc @YoseopYoon !
RBBP6 anchors pre-mRNA 3′ end processing to nuclear speckles for efficient gene expression: Molecular Cell https://t.co/QTK9XaPrW0

[Genes & Development @GenesDev]

In this Review, La Fleur et al. dive into the world of massively parallel reporter assays (MPRAs) in studying RNA and gene regulation. @YongshengShi @seeliglab
Learn more about the power of MPRAs in therapeutic design when coupled with machine learning:
➡️ https://t.co/3jG4G5DN7N

[Yongsheng Shi @YongshengShi]

My department is hiring a tenure-track faculty focusing on RNA biology!
@UCIrvine has a large, vibrant and super supportive RNA community! Come join us!
https://t.co/cc3di1SFma

[Yongsheng Shi @YongshengShi]

Interested in working on RNA processing and degradation? Come join us!
My lab is recruiting at all levels!

[Yongsheng Shi @YongshengShi]

I'm glad that our paper on the anticancer compound JTE-607 has come out in 2023 in @NatureSMB ! Congrats to first authors Liang Liu and @angelamyu
https://t.co/UZ7hn7qKqH

[Liang Liu @Liang_Liu_]

Excited to share my most recent work in @NatureSMB on mRNA 3' processing and the anticancer compound JTE-607: https://t.co/E4eDDazLCD. A huge thank you to my PI @YongshengShi, my collaborators @angelamyu and @seeliglab, and amazing lab mates @YoseopYoon @LVSoles and @mariiellee1

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.

[Liang Liu @Liang_Liu_]

Congrats Roberto and Emily!! Heard this story a few times in the past and nice to see it finally came out!

[TinocoLab @tinoco_lab]

HMGB2 regulates the differentiation and stemness of exhausted CD8+ T cells during chronic viral infection and cancer. Sharing our newest discovery from our lab. So proud of my Ph.D. Student Emily Neubert and team!! https://t.co/QmmQUvLIVq

[Liang Liu @Liang_Liu_]

Fantastic #cshlmRNA 2023 conference with @LVSoles and @YongshengShi!!! 2nd cold spring harbor conference that I attended but 1st one in person and 1st one attending as a postdoc 🎓 Wait for me to come back in 2025!

[Liang Liu @Liang_Liu_]

@AliciaChi8 Lol I can’t get R to work and I hate learning it. I’m just trying to master my wet lab skills so I can do certain techniques that others cannot do

[Liang Liu @Liang_Liu_]

@JessieAltieri Good luck!!!

[mark belan | science illustrator + info designer @markabelan]

The Many Shapes of Bacteria

#infographic #bacteria #microbes #biology #science #design #illustration #art #sciart #shapes #geometry #microbiology

[David S. Goodsell 🏳️‍🌈 @dsgoodsell]

Finished "Bacteriophage T4 Infection" this morning. The thin white line at left, which folds up and down 10 times, depicts the length of the T4 genome. After I add a few finishing touches and make sure I haven't forgotten anything, I'll put the full-size file @buildmodels.

[David S. Goodsell 🏳️‍🌈 @dsgoodsell]

Close up of the newly-infected bacterial cell from "Bacteriophage T4 Infection." I drew the illustration in Photoshop at a scale of 1 pixel/nanometer.

[Liang Liu @Liang_Liu_]

It was a wonderful 6 years spent in @YongshengShi Lab and I’m so happy we all graduated together Kristianna and @LVSoles !!!

[Yongsheng Shi @YongshengShi]

A record for the lab: three students graduated in one year! 🎉🎊They (⁦Kristianna, @LVSoles, and Liang)⁩ joined around the same time and fundamentally transformed the lab. I’m forever grateful and can’t wait to see what they will achieve in the future! ⁦

[Lindsey Soles 🌻 @LVSoles]

So incredibly proud of my wonderful undergrad, Alice, who did an amazing job presenting her research at the UCI UROP Symposium today!! (Redacted to create anticipation for upcoming findings 🤫)

[Junwei Shi @junwei_s]

Excited to share our new work on direct protein-based genome editing in primary cells. We termed it Peptide-Assisted Genome Editing (PAGE) CRISPR-Cas platform. This platform allows rapid and effective editing of primary cells with minimal toxicity. https://t.co/tRdFwotwcW

[Yongsheng Shi @YongshengShi]

New preprint from our lab and a great collaboration with @seeliglab !

The anti-cancer compound JTE-607 reveals hidden sequence specificity of the mRNA 3' processing machinery https://t.co/audwUX6ZI2

[Lena Muckenfuss @LenaMuckenfuss]

Happy to share our recent insights into eukaryotic mRNA 3' end processing where we dissect the molecular interactions of hFip1. It took only a pre-print to make me tweet :) Thanks to everyone involved! @MartinJinek https://t.co/kzKEexzQdg

[Di Jiang @dijiang319]

Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome https://t.co/rDwjd6ZbuV