Lina Diaz-Gallo

wife, mom, scientist, genetics and genomics of autoimmune diseases, aiming to contribute to translational research and prevention-precision medicine of RMD

[Lina Diaz-Gallo @LinMarDiaz]

Our unique work studying T-cells from the inflammation site of patients with myositis on a single-cell level is out 🧵1/3 https://t.co/Y1abh6jmCM

@KarineChem65601 @alexandra_argy @begum_h @AngelesShunashy

[Karolinska Institutet @karolinskainst]

#Myositis can be grouped into eight subgroups of patients by combining genetic information and blood markers (#autoantibodies). The KI study is published in @eBioMedicine by @LinMarDiaz et al and may lead to improved diagnosis and treatment. #rheumatology https://t.co/LbUJNsxLrn

[Lina Diaz-Gallo @LinMarDiaz]

@gamonasterioo @bckbianca @ACDbio A beautiful pic

[Lina Diaz-Gallo @LinMarDiaz]

@braraposo @karolinskainst 👏🏾👏🏾👏🏾

[Noseda_lab @NosedaLab]

Excited to share our editorial on #scRNAseq in idiopathic inflammatory myopathies, out today in @EmboMolMed Congrats to Argyriou et al on their study, advancing our understanding of this complex disease!
@NosedaMichela @momina_yazdani @Mach_MD

https://t.co/q3eTS59AyZ

[Lina Diaz-Gallo @LinMarDiaz]

@eBioMedicine

[Lina Diaz-Gallo @LinMarDiaz]

Autoantibodies profile and #HLA may help to better classify patients with #myositis Why? Check our study:
https://t.co/b8sH0DfRSa

@ingrid_lundberg @Leopad12 @drhectorchinoy @SarahLTansley
@AngelesShunashy

[Lina Diaz-Gallo @LinMarDiaz]

Autoantibodies profile and #HLA point to pathogenic pathways in #myositis

⁩ Figure made by⁩
⁦⁦⁦@AngelesShunashy⁩ https://t.co/fujomxYfz0

[Karolinska Institutet @karolinskainst]

@KarineChem65601 @EmboMolMed Link to publication ⬇️
https://t.co/o6kxG26dA0

[Karolinska Institutet @karolinskainst]

T cells in the muscle tissue of patients with idiopathic inflammatory myopathies was characterized by @KarineChem65601 et al in a study in @EmboMolMed. The results show that the same T cells persist in the muscle despite immunosuppressive treatment.
https://t.co/wx9tlSPjGK

[Lina Diaz-Gallo @LinMarDiaz]

Persistent T cells identified in the muscle of patients with idiopathic inflammatory myopathies | Karolinska Institutet Nyheter https://t.co/W6Kt0rgjYB

[Lina Diaz-Gallo @LinMarDiaz]

T-celler stannar kvar i musklerna hos myositpatienter trots behandling | Karolinska Institutet Nyheter https://t.co/xbJ6Okqcie

[EMBO Mol. Medicine @EmboMolMed]

📢#SingleCellProfiling of muscle-infiltrating #Tcells in #IdiopathicInflammatoryMyopathies

By A. Argyriou, B. Horuluoglu, @LinMarDiaz, @KarineChem65601 & colleagues @karolinskainst

🗞️ #openaccess: https://t.co/fDrPYKP6J8

[Lina Diaz-Gallo @LinMarDiaz]

3/3 Identical expanded T-cell clones persisting at follow-up in the muscle of two patients suggest their involvement in disease chronicity.

[Lina Diaz-Gallo @LinMarDiaz]

Our unique work studying T-cells from the inflammation site of patients with myositis on a single-cell level is out 🧵1/3 https://t.co/Y1abh6jmCM

@KarineChem65601 @alexandra_argy @begum_h @AngelesShunashy

[Lina Diaz-Gallo @LinMarDiaz]

2/3 Clonally expanded T-cell clones were mainly found amongst cytotoxic and resident memory T cells implying their role in the disease pathogenesis.

[Lina Diaz-Gallo @LinMarDiaz]

1/3 We identified a tissue resident memory T-cell signature in the muscle biopsies of all patients with myositis included in this study

[nature @Nature]

Sweden’s researchers outraged at decision to axe development-research funding https://t.co/gt3XXskcSu

[Lina Diaz-Gallo @LinMarDiaz]

@alexandra_argy @riken_en @begum_h @AngelesShunashy @Myositis_KI Well done! Keep enjoying the course and Japan

[Alexandra Argyriou @alexandra_argy]

Day 3 at @riken_en and here presenting our single-cell study in muscle-infiltrating T cells in idiopathic inflammatory myopathies
@LinMarDiaz @begum_h @AngelesShunashy @Myositis_KI

[Human Protein Atlas @ProteinAtlas]

Version 23 of the Human Protein Atlas is released including an updated genome assembly, a new Interaction section with data for human protein-protein interaction networks, and lots of other updates.

Read more
https://t.co/zHLwm2muUd