Lisa Barbaro

Medicinal chemist at @WCNDD_TN
Passionate about #mentalhealth research and awareness
Aussie in the USA | Avid lover of dad jokes

[Lisa Barbaro @LisaBarbaro]

Here's a time-lapse of my column fractions growing crystals... Always a pleasure to watch, especially on a bad day! #RealTimeChem #Chem4Life

[Lisa Barbaro @LisaBarbaro]

@wessel_burger @Thal_DM Congrats!!

[Lisa Barbaro @LisaBarbaro]

Nirmatrelvir (PF-07321332) (the antiviral agent in #Paxlovid) wasn’t even a sketch in a medicinal chemist’s lab notebook 2 yrs ago!

[C&EN (Chemical & Engineering News) @cenmag]

Doctors are hoping that Paxlovid, Pfizer’s oral COVID-19 treatment, could be a lifeline for some. This is the story of how this antiviral came to be (by @beth_halford): https://t.co/sKu89I6tKG

[Lisa Barbaro @LisaBarbaro]

This is a really cool method to introduce late stage methyl groups from the @SongLinLab! A little reminder we recently published on the dramatic pharmacological effect a single #magicmethyl can have on a small molecule.

[J. Am. Chem. Soc. @J_A_C_S]

Exploring Electrochemical C(sp3)–H Oxidation for the Late-Stage Methylation of Complex Molecules @CornellChem @Cornell @genentech @UMNCSE @TotalSyntheses #Electrochemistry #Oxidation #Latestage #Methylation @SongLinLab @songlin_chem https://t.co/qZKtRzHNLz

[Lisa Barbaro @LisaBarbaro]

Happy (belated) #NewYear2022! After a long hiatus I'm making an effort to be more active on Twitter this year. How do I use this again haha? #imback

[Lisa Barbaro @LisaBarbaro]

@samuel_b_phd @LindsleyLab Many thanks Sam!

[Lisa Barbaro @LisaBarbaro]

@chrislangmead @Neuromedicines @MonashPharm @MIPS_Australia Exciting news, congratulations Chris!

[Squire J. Booker @BookerMan_PSU]

Super-excited to see another great contribution in ACS Bio & Med Chem Au, ACS's premier fully open access journal dedicated to biochemistry, chemical biology, pharmacology and medicinal chemistry!!! https://t.co/9b0Ud2se4c

[Lisa Barbaro @LisaBarbaro]

@MilesCcc @WCNDD_TN @ACSBioMed Thank you!

[Lisa Barbaro @LisaBarbaro]

New paper alert! We discuss our discovery of #MolecularSwitches within a series of mGlu5 allosteric ligands driven by an interesting 'magic methyl' effect.
https://t.co/Wlw3XxqclY @WCNDD_TN @ACSBioMed

[ACS Publications Bio & Med Chem Content @ACSBioMed]

Discovery of ‘Molecular Switches’ within a series of mGlu5 allosteric ligands driven by a ‘magic methyl’ effect affording both PAMs and NAMs with in vivo activity, derived from an M1 PAM Chemotype
Craig Lindsley et al. @VUMChealth
ACS Bio & Med Chem Au
https://t.co/wrv4iq6wyy

[Lisa Barbaro @LisaBarbaro]

@tawareniel Sanofi and Glaxo are very far from sketchy off brand companies hahaha 😅

[Lisa Barbaro @LisaBarbaro]

I'm a little late but very happy to have this work from my PhD published! A big effort by all involved

[Lisa Barbaro @LisaBarbaro]

@chrislangmead @ausmedchemist Thanks!!!

[Lisa Barbaro @LisaBarbaro]

@StefanBader1987 @bio_nano @ONJCRI @latrobe @MIPS_Australia @LTUresearchers @MonashPharm Woohoo!! A big congrats!

[Lisa Barbaro @LisaBarbaro]

@harry_wasity Let's hope those mail in ballots get counted! It's going to be veryyyy close

[Lisa Barbaro @LisaBarbaro]

@AnithaK_PhD Offttt!!

[Lisa Barbaro @LisaBarbaro]

@samuel_b_phd @posthuman Wow I bet!! So cool

[Lisa Barbaro @LisaBarbaro]

@samuel_b_phd @posthuman Wow that's amazing, how did that come about?

[Lisa Barbaro @LisaBarbaro]

@__Joe_Egan__ @sarahdcady Wow that's just so cool!!

[Lisa Barbaro @LisaBarbaro]

When the crude compound was brown, but the the column fractions revealed something more funky to brighten up the evening. #RealTimeChem #CENchempics #chemtwitter

[Lisa Barbaro @LisaBarbaro]

@chemkramer @sarahdcady Wow that sounds awesome!! The little surprises are well worth, hopefully it was ur product as well!