The capstone of @joycejoy22 PhD with @NUSMedicine is a great review not only of the recent advances in blood biomarkers for AD but also of the technology behind the high sensitivity. Everything you wanted to know about techniques but were afraid to ask! https://t.co/NNPKuXRsmJ
Glad that together with @HilalSaima@CamStroke@ISD_Research@DondersInst et al, we have established the OPtimising mulTImodal MRI markers for trials of Vascular Cognitive Impairment due to cerebrAl small vesseL disease collaboration and its 1st paper
https://t.co/RmusYf1nIy
Another excellent paper from @LutingPoh and @garriearumugam on how hypoperfusion activates the inflammasome even in the cerebellum
https://t.co/VNdOxTM7I8
Our Healthy Longevity programme featured by @NUSMedicine. Thanks for highlighting the SINGER multiple lifestyle intervention study!
https://t.co/D0RHKFMLIF
Well done @LutingPoh and @garriearumugam for showing that Intermittent Fasting attenuates the inflammatory response and cell death pathways in the brain following chronic hypoperfusion in a mouse model of vascular cognitive impairment (VCI).
https://t.co/oxHXMdXWAa!
I am very happy to be part of this excellent work published in Science Advances. Our data establish the influence of O-GlcNAcylation on Aβ accumulation and neurodegeneration, suggesting O-GlcNAcylation–based treatments as potential interventions for AD.
https://t.co/C5itg4FQPr
congratulations to @YuekLing_Chai for her work on circulating osteopontin, a marker for inflammation, as a biomarker for cognitive impairment and dementia as well as MRI changes
https://t.co/E9HwB30GqM
Excellent first paper by masters student Mervyn Lim supervised by @HilalSaima on the effect of intracranial stenosis on executive function over time
https://t.co/w2U3zYfYXf
Another important consequence of cortical cerebral microinfarcts which are associated with incidence and progression of geriatric neurobehavioral disturbances, independent of conventional SVD markers. https://t.co/OwG40bwDCC
Great paper by @joycejoy22 with @NicholasAshton@TommyKakari and colleagues in Gothenburg on how useful blood biomarkers are in Asians with cognitive impairment and dementia
https://t.co/lvghYMQoEf