Incredibly happy and proud to share our newest work in @ScienceTM showing that Aβ promotes neuronal hyperconnectivity, thereby driving tau spread across connected brain regions. Many thanks to to first authors @SebRoemer and Fabian Wagner!
https://t.co/irKeFkbsz6
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The ISD co-organized the 9th International Conference on Cerebral Amyloid Angiopathy located at the Kardinal Wendel Haus next to English Garden/Munich. Experts presented latest developments in CAA research ranging from basics in research to studies in humans...
Did you ever wonder why the risk for subsequent vascular events is increased after a first stroke or MI?
Our answer, out now in @Nature https://t.co/lsANUymvOz
A story about NETosis, DNA-sensing and inflammasome activation. Spearheaded by @StefanRoth86 and Jiayu Cao.
Finally out today! Very proud of this story:
Innate immune memory after Stroke drives remote organ pathology
This study was led by superstar-postdoc @SimatsAlba and X-less Sijia Zhang. @CellCellPress
https://t.co/0pvrxibv6P
Authors from @ISD_Research, @unidue_zmb and colaborators develop repair approaches to reverse the effects of pathogenic mutations in protease HTRA1.
https://t.co/Z8VqF4o27b
Excited to share our newest work showing that neuroinflammation parallels tau spread in 4R tauopathies, suggesting a key role of microglia in tau progression. Many thanks to @M_Malpetti, @RoemerSeb, @johanneslevin, @GunterHoglinger and @matbrendel
https://t.co/WxRDmXAjNd
October 15-17 9th ICAA in Munich, ISD co-organizing 9th Interational Conference on Cerebral Amyloid Angiopathy in Munich. Experts will present latest developments in CAA research ranging from basic research to studies in humans. Sign up now: https://t.co/A2LHuTbg8E
ISD teams gathered for annual scientific retreat to present their projects and discuss work. There were presentations from Ph.D. students, a poster session, invited speaker talks, and an amazing three minute thesis competition. @PaquetLab@JekyllSarah @mgeorgakis1
The 30th ISGC Workshop is in full swing! Thank you to everyone contributing to talks, posters and vivid discussions 🧠🩸🧬🔬
And a big thank you to our host @rainermpg and the @ISD_Research 🎉✨️🎊
What honor to host the ISGC workshop, here at the preciousLMU St.-Vinzenz-Haus Munich City Great Keynote Lectures and Scientific Sessions and social activities #strokegenetics https://t.co/OglHG8yYWi
Very excited to share that our DELiVR method is now open access published @NatureMethods. We created a simple, brain-wide cell analysis deep learning tool, no coding needed! Fiji Plugin makes it accessible to all. https://t.co/qjFk3p5aba
by @Dorie00@Rami96614090 @moritz_negwer
Age-related decline in brain endothelial cell (BEC) function contributes critically to neurological disease.(…) A study by isd investigators 👉@katalin_volgyi@Judit_GonzalezG et al. just published on @NatureAging
read more here https://t.co/Fo0rOJI6Zu
#OriginalResearch: Proteogenomic data integration reveals CXCL10 as a potentially downstream causal mediator for IL-6 signaling on atherosclerosis #AHAJournals https://t.co/GspSdiK2LF
Super happy to share our new work out in @NatureComms, showing that synaptic changes accelerate amyloid-related tau accumulation and spread in #Alzheimer's disease. Many thanks to @_michael_scholl and many others!
@ISD_Research, @goteborgsuni
https://t.co/QvEiZMa9JU
First results from 2,500 individuals from eMERGE, a study developed to test genomic risk assessment at a population level.
Important PRS data for 10 diseases on:
👉performance
👉feasibility
👉medical actionability
👉translatability
https://t.co/H6yz6NyMuC
A useful resource on the national prevalence of carotid atherosclerosis in China (>10M individuals) @JAMANetworkOpen
👉 increased cIMT (>1mm): 26% | 93% (!) for >80y
👉 plaque: 21% | 87% (!) for >80y
👉 stenosis: 0.6% | 4% for >80y
https://t.co/K3Tyszcloa
We are happy to present the new BRENDA Leducq Website with all information about the project, talks, meetings, and other news #brenda@FondationLeducq
https://t.co/It9sHy5tEH