𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎

Geneticist & analyst of ancient and modern populations. Exploring history, peoples, and languages

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

🎉 1,132 USERS — THANK YOU! 🧬

Today we reached 1,132 registered users on MADAI LABS!

Even more incredible:

📊 675 MADAI Kit uploads have already been submitted by the community.

What started as a small genetics project has grown into a platform where thousands of analyses are performed, samples are shared, and people from all backgrounds can explore population genetics, ancient DNA, and family history together.

A huge thank you to everyone who:

• Uploaded their DNA
• Tested our tools
• Reported bugs
• Shared feedback
• Created models and research
• Supported the project

MADAI LABS would not exist without you. ❤️

We still have a lot planned:

🚀 More tools
🧬 More datasets
📈 Better modeling
🌍 Larger sample collections

Thank you for being part of this journey.

🔗 Website: https://t.co/XVYWfLukdx
💬 Discord: https://t.co/HiiHTPB4As
📢 Telegram: https://t.co/51VnUqvqTV

#Genetics #AncientDNA #PopulationGenetics #DNA #Genealogy #MADAILABS #qpAdm #Archaeogenetics #Bioinformatics #Genomics 🧬🔥

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

@Pashtun_NoCares @Avni1040070 Do you do it with plink2 or mergeit

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

🧬 MADAI0077 — Turkey_Giresun_Turkish.MD 🇹🇷

Y-DNA Haplogroup:
🔹 Q-M120

Ethnic Information:
🇹🇷 Turkish
📍 Giresun, Turkey
👨 Father’s Ethnicity: Turkish
👩 Mother’s Ethnicity: Turkish

qpAdm Admixture Model (2-Way) 🧬

✅ PASS | ✅ Feasible
📊 p-value: 0.666
📈 Fit: Excellent
📉 chisq: 1.57

Ancestry Composition:

🔴 51.1%
Turkey_Aegean_Mugla_Stratonikeia_Byzantine.AG

🟠 48.9%
Kazakhstan_Southeast_Karakhanid.SG

This model was generated using ADMIXTOOLS (qpAdm), a statistical framework used to test and model ancestry proportions between ancient and modern populations.

The result suggests a nearly balanced ancestry profile between an Anatolian Byzantine-related source and a medieval Karakhanid Turkic source.

🌐 Website:
https://t.co/XVYWfLtMnZ

💬 Discord:
https://t.co/HiiHTPAwKU

#DNA #Genetics #TurkishDNA #Giresun #QM120 #qpAdm #ADMIXTOOLS #PopulationGenetics #AncientDNA #Turkic #Karakhanid #MADAILABS

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

@Pashtun_NoCares @Avni1040070 It does tho. Thats how mergeit works. If you have 600K snps on myheritage only 200K of them are in the 2M snp panel.

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

@Pashtun_NoCares @Avni1040070 The snps get trimmed in the merging process. If i merge myself with 2M dataset my commercial kit snps will get trimmed based on the 2M snp panel. I dont get what you mean

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

@Pashtun_NoCares @Avni1040070 Which issue did you get while merging? Do you have a screen?

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

@Avni1040070 @aldersimi Little inbred rate

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

@Avni1040070 Nope. Its against the data agreement. Raw file downloads from the website are not available

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

@Avni1040070 Kurmancim

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

🧬 The official MADAI LABS Discord server is now live.

Join our growing genetics community focused on:

⚔️ Ancient DNA
🌍 Population Genetics
🧪 Y-DNA & mtDNA
📊 qpAdm / Admixture
🏺 Ancient Civilizations
💬 Debates & Discussions

Join now:
https://t.co/ZnPRDArEcy

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

Es ist interessant wie die leute mit diesen samples spielen und es deuten wie die wollen. Wie gesagt das R1b-z2103 in dersim ist via catacomb->lchashen metsamor>early armenians gekommen. Des bestreitet keiner. Betrifft aber mehrheitlich nur zazas aus dersim. Die samples dort haben nicht wirklich viel mit uns zu tun. G25 distanzen sind basierend auf PCA plots und nicht wirklicher abstammung. F-Stats sind hierfür eher gedacht. Ausserdem sind uns nur die samples nah die "tepe hissar" und proto armenisch ähnlichen einfluss haben. Würde es diesen "tepe hissar" einfluss nicht geben würden diese 4-5 samples nicht mal ansatzweise mit uns clustern. Y-dna technisch brauchen wir sowieso nicht reden da diese individuen ganz andere claden als wir tragen (außer zazas aus dersim). Wie gesagt diese refferenzen haben nicht viel mit uns zu tun. Die hurriter, lullubäer und etc sind schon lange vor indo iranischer ankunft von ihren nachbarn assimiliert worden. Es ist auch immer wieder lustig wie leute Hasanlu_IA als pur hurritisch deklarieren wobei es schweren proto armenischen einfluss hat und bmac einfluss hat. Das einzige was man als hurritisch oder hurro-urartian deklarieren kann ist vielleicht sirnak_ba. Die leute kommen aber mit dem argument und sagen "saaar es clustert aber mit semiten wie kann das sein". Das liegt eben daran das es ein mix aus israel_c und sehgabi_c ist. Es ist vollkommen normal das es zu semiten eher clustert wenn es garkein steppe hat. Die leute sind aber zu dumm und hängengeblieben um darüber mal nachzudenken. Stattdessen nennen die jedes scheiss sample um nach "gutian, lullubian, hurrian" wie gesagt einfach auf die studie warten

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

🚀 PERSONAL DATASET RELEASED ON MADAI LABS 🧬

For everyone who enjoys ancestry modeling, I've decided to make my own family dataset publicly available on MADAI LABS.

📌 I am MADAI0001

You can find my ethnic background and sample information in the Sample Dashboard.

📊 Dataset details:

• MADAI0001 (my sample) → ~468,000 SNPs
• Remaining samples → ~200,000 SNPs each
• Includes my father, grandfather, uncles, and other close relatives

This gives you a unique opportunity to model a real extended family dataset and compare different generations against ancient and modern populations.
Feel free to:

✅ Run qpAdm models
✅ Test F-statistics
✅ Compare different references

💡 Small modeling tip:

I've noticed that Georgia_Kotias_Mesolithic.SG behaves somewhat strangely in my models.

For me, Georgia_Satsurblia_LateUP.SG often performs better as a CHG-related source.

Try both and compare the results for yourself.
If you make any posts, threads, qpAdm models, or interesting discoveries using the dataset, tag me — I'd love to see what people come up with. 🔥
Have fun modeling! 🧬
#AncientDNA #PopulationGenetics #qpAdm #AdmixTools #Genomics #MADAILABS #DNA #Archaeogenetics #CHG #Genetics

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

Thats true. If you want to check actually ancestry you will have to do it via F-Stats. Even on f-stats tho they will be closer than us. We already checked that with dinkhatepe1 and 2 and even hasanlu. Only 5-6 samples cluster with us and the only reason is because they have som tepe hissar like influence. If they wouldnt have this we wouldnt be close to those 5-6 samples

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

@aldersimi Neither. Its just the admix of high proto armenian with native Mesopotamian which is the reason assyrians and armenians cluster closer. Native mesopotamians didnt survive that long and got replaced by proto Armenian individuals in LBA

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

🚀 BIG UPDATE: Kinship & ROH Profiler is now live on MADAI LABS! 🧬

Ever wondered how closely related your parents were?

Our new Kinship & ROH Profiler analyzes your autosomal DNA and provides:

✅ FROH (Runs of Homozygosity) score
✅ Estimated parental relationship (1st–5th cousin range)
✅ Visual cousin-degree scale
✅ Breakdown of homozygous segments by length
✅ Detection of recent shared ancestry vs. deeper isolation
✅ Insights into endogamy, founder effects, and consanguinity

You can analyze:

• Your existing MADAI KIT

• A raw DNA file from 23andMe, AncestryDNA, or MyHeritage

This adds another powerful population genetics tool to the MADAI LABS ecosystem — completely FREE.

🌐 Try it now:
https://t.co/XVYWfLtMnZ
#Genetics #PopulationGenetics #DNA #ROH #FROH #AncientDNA #Genealogy #MADAILABS #Bioinformatics #Genomics 🧬🔥

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

@KurdiCompendium From which study are those samples?

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

@Rashavandi @bilz_27 Using HLA lmao🤦‍♂️

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

@KurdiCompendium Look in dm

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

Y-Full finally split up my subclade. FTA62902 now has 2 daughter lines. FTA62902* and FTG40986 (Y79641). I will test more and more people around my region to look from whom we got FTA62902. Or maybe we can find a clade between Y93512 and FTA62902. Lets see

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

@kvali_app There is one akbari sample which is scytho-sarmatian related. Most samples tho are tocharian. There is also one tajik with my forfather clade on familytreedna. The clade is most likely eastern iranian or turkic related

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

@TarimEMBA Olucak*

[𝙈𝘼𝘿𝘼𝙄 𝙇𝘼𝘽𝙎 @MADAILABS]

@TarimEMBA Almanyada yaşiyorum. Biraz zor ulucak ama bakacam. Bu arada benim site de Y dna prediction var ve yfull gibi ayni sistem var. istersen kendini upload yapabilirsin. Şuanda tek vcf var ama 1-2 gün sonra BAM support de var