@AGhanbarpour is at it again with another beautiful #cryoEM preprint on the AAA protease ClpXP. His structure newly reveals how the SspB adapter protein delivers substrates for degradation. Great collab w\ Sauer & @taniamitclper labs! Details of our 3 key insights follow 1/n.
@kbrogala @mlvalenstein Amazing work! Immensely gratifying to see this outcome from your persistence, wrangling 🐊2 to behave for #cryoEM. Look forward to displaying your intriguing hollow structure outside the Krios and Arctica in @mit_nano basement corridor!
@MDarrow7 @TalyaLevitz @SPTLabtech @Drennan_Lab @Chaz_chameleon Thank you @MDarrow7 for your guidance from the moment @Chaz_chameleon rolled out of his crate into the lab. We’ve learned so much from you at all steps of the project, from new ways to think about sample prep to imaging to analysis, every step of the way.
@TalyaLevitz @MDarrow7@SPTLabtech @Drennan_Lab @Chaz_chameleon Congratulations @TalyaLevitz on crossing the finish line with your fundamental study of what new #CryoEM sample prep technology can enable. Can’t wait to see what fast-dispense grids we image next!
Graduate student Ellen Zhong helped biologists and mathematicians reach across departmental lines to address a longstanding problem in electron microscopy. “Collaborations between disciplines are the future,” says Bonnie Berger, one of her mentors. https://t.co/6HnjfivTiu
MIT.nano recently launched a new pilot program, START.nano, to support hard-tech ventures in their early stages. Seven companies with nanoscale technologies at the core of their business have been accepted.
Read more! https://t.co/VtXfY3xAVb
#nanoscience#startups#research
Aquilos ~1.5 upgrade in progress, halfway from generation 1 to 2. Will the Krios be able to collect tilt series as fast as we can make lamellae? @thechaolab @aschuller17@thermosciEMSpec
@JinhuDou shouting “HEXAGONS!” could be heard from the Krios control room down the basement hallway of @mit_nano. And did @DincaGroupMIT just set a record for most SI figures in a paper?
Excited to share this gargantuan amount of work in one paper, getting to single crystals of 2D conductive MOFs: https://t.co/KrFHT0DaEG Big congrats to my postdoc @JinhuDou, and many thanks to collaborators @chhendon@MaxxSolidChem and many twitter-less others
Join us tomorrow at 11:30 a.m. ET via livestream for the first lecture in our new series: "COVID-19, SARS-CoV-2 and the Pandemic." You'll hear from Professors @youngricka and Facundo Batista, as well as guest speaker @brucedwalkermd. Details: https://t.co/xwGJ079B85
@kbrogala @DMSabatini@MITBiology@ScienceMIT @HHMINEWS “Our team at MIT.nano, which is our second home, and a place where we image our proteins with electron microscopes under cryogenic conditions. The white wardrobe-looking piece is a powerful electron microscope inside of an enclosure!”
—@kbrogala
@MITcryoEM@mit_nano
mTORC1 is a master regulator of cell growth. A study led by @kbrogala in @DMSabatini’s lab refines the model of how mTORC1 binds the Rag-Ragulator complex and docks with the lysosome, where it can become activated. https://t.co/1qnh8AKW5d
@MITBiology@ScienceMIT @HHMINEWS
.@techreview talked to @aschuller17 and other Schwartz lab researchers about modeling, building, and repairing things at an atomic scale inside the @MITcryoEM facility: https://t.co/skq39rJGsQ