The scary part about Anthorpic's Fable nerf is not that it refuses to answer biology or cryptography. It's that it foreshadows what's coming. A world where a couple companies decide what you can and cannot do. They're building a new ruling class and you're not in it...
From what multiple Trump administration accounts are focusing on and re-posting, the White House is going to try to sell the deal on a single point: "Iran must agree that they will never have a nuclear weapon."
(Which was point "iii" of the JCPOA's Preamble: "... Iran reaffirms that under no circumstances will Iran ever seek, develop or acquire any nuclear weapons...")
At @plcapital we believe the GPT moment for robotics is closer than many believe, with innovation in the sector rapidly advancing and we see cryptographic and decentralized primitives as central to this narrative 🧵 1/5
Here is Episode 2 of my new podcast dedicated to conversations on the future of neurotech, computing, intelligence, and more.
My guest Dr. Ben Rapoport is co-founder and CSO of Precision Neuroscience (@PrecisionNeuro_), Assistant Professor of Neurosurgery at the Icahn School of Medicine at Mount Sinai, and Scientific Director at Mount Sinai. Previously, he co-founded Neuralink and Simbionics (acquired by Apple).
Precision is building a minimally invasive brain-computer interface (BCI) that reads from thousands of points on the cortex without penetrating it. The Layer 7 device is implanted through a one-millimeter slit in the skull rather than the larger borehole other approaches require. It is also fully removable.
Precision seeks to help the 5 million people living with severe paralysis in the US (including 800,000 new stroke cases per year). In March 2025, Precision received FDA clearance for a temporary wired version of the system. Over 85 patients have been implanted with and used the device in clinical studies (50 at the time of our conversation). Wireless implants are planned for 2027.
We go deep on the history of Neurotech from the 1980s to the ML inflection points that triggered Neuralink's founding, why surface ECoG was a contrarian bet that's now paying off, the path to treating paralysis and stroke at scale, and why Ben believes neural data is at the same inflection point genomic data was in 2000 — a whole class of biological problems about to become tractable as computer science problems.
Chapters
00:00:00 Introduction
00:04:39 Paralysis as a lens to understand the brain
00:05:36 The 1980s breakthrough: population encoding and the birth of BCI
00:14:36 Google Translate, ML, and the founding of Neuralink
00:23:08 What is the long-term vision of Precision Neuroscience
00:31:56 Layer 7 and why transformative technology looks impossible at first
00:50:21 The surgery: a slit in the skull, not a borehole
00:55:19 The clinical program: who are the patients
01:04:16 FDA clearance and the path to wireless implants in 2027
01:08:32 The patient population: paralysis and stroke at scale
01:16:26 Neural data as the new genomics
01:30:06 BCIs, AI, and the future of the human-machine interface
01:31:22 From medical necessity to lifestyle technology
01:40:36 Precision as a platform — and an optimistic vision
If you're interested in these kinds of discussions, subscribe to the podcast. And if there’s anyone you’d like to see or hear on the podcast, reply with your suggestions.
Full Episode 2 here and in other platforms below.
So @MJ_C12 and I built a thing yesterday at AgentsDay: a single MCP that lets you (or your agent) analyze a webpage, scan the top three prediction markets and returns any positive EV bets related to the content of the webpage.
MIT open source. Built on @Cloudflare link below.
Excited to launch a new podcast dedicated to conversations on the future of neurotech, computing, intelligence, and more.
First guest: @maxhodak_ founder & CEO of @ScienceCorp_, which is building PRIMA, a retinal prosthetic that’s restoring meaningful vision for patients with blindness caused by age-related macular degeneration.
Science is also developing a biohybrid brain implant that grows living neurons directly onto a silicon chip, then interfaces that system with the cortex. The possibility space here is vast and new. Imagine growing new areas of the brain.
Sections
00:00 What counts as neurotech?
01:45 History of brain-computer interfaces and the smartphone dividend
07:25 PRIMA - How Science is restoring vision in blind patients
10:10 Why stimulating bipolar cells works when the optic nerve doesn't
30:30 Are we bottlenecked by biology or engineering?
32:40 Expanding the brain's bandwidth beyond 10 bits per second
37:00 Can we add new areas to the brain?
37:46 Biohybrid BCIs: neurons growing on a chip
39:20 What could neural augmentation look like?
01:13:20 How Science drives Fast R&D
01:44:00 How founders learn and level up
This is the kind of discussion I’m excited to explore on this podcast. Enjoy!
Full Episode 1 here and in links below.
the strait of hormuz is in a quantum superposition of open and closed that only collapses when you try to take a tanker through yourself and see if you get shot at
The world’s most important price for physical oil barrels soared to its highest on record. Dated Brent, which helps price much of the world’s actual oil barrels, hit $144.42 on Tuesday, according to Platts, a unit of S&P Global Energy.
Today, several teams at the EF are launching https://t.co/MtJ95Ah4z6, a dedicated resource for Ethereum's post-quantum security effort.
What started with early STARK-based signature aggregation research in 2018 has grown into a coordinated, multi-team effort, all open source.
The Post-Quantum team and Cryptography teams, with help from the Protocol Architecture and Protocol Coordination teams, have been working on this body of work for 8+ years.
At https://t.co/MtJ95Ah4z6 you'll find:
- How PQ impacts each protocol layer
- The full PQ roadmap (https://t.co/gPl9StdPSp)
- Open resources: repos, specs, papers, EIPs
- FAQ: 14 questions across 5 categories, written by the PQ team
- A 6-part lean Ethereum interview series (@zeroknowledgefm)
- Interest form for the 2nd Annual PQ Research Retreat (Cambridge, UK, Oct 2026)
- 10+ client teams are already building and shipping devnets weekly through PQ Interop.
All the work is public and all of it is open.
https://t.co/MtJ95Ah4z6
https://t.co/EtEPn2R6uL I worked on this book about the end of the age of oil 20 years ago
Oil has always been THE national security risk: the world runs on flammable gas in thin steel pipe. You poke a hole and the world burns.