Marcel Tomaszewski

Interventional endoscopist, gastroenterologist, Hôpital du Sacré Coeur de Montréal, @CIUSSSnmtl, @UMontreal

[Mark Lewis, MD, FASCO @marklewismd]

Cheers, chills, and a standing ovation when RASolute 302 showed unprecedented survival on daraxonrasib for patients with progressive pancreatic cancer

Seldom do you sense you’re witnessing a historic moment in cancer care but this feels like ras targeting has arrived

#ASCO26

[NEJM @NEJM]

Presented at #ASCO26:

Among patients with previously treated metastatic pancreatic ductal adenocarcinoma, the RAS(ON) inhibitor daraxonrasib led to significantly longer overall survival and progression-free survival than chemotherapy. Full phase 3 RASolute 302 trial results: https://t.co/xwLWBZYRzq

@ASCO

[The Baveno Cooperation: an EASL Consortium @BavenoCoop]

📜 Anticoagulation for PVT in cirrhosis
🗣️ N. Riva |
💡 Treat based on: LT candidacy, thrombus extension & cirrhosis severity
🔬 DOACs in cirrhosis:
✅ Child A → all DOACs OK
⚠️ Child B → apixaban/edoxaban with caution, avoid rivaroxaban
❌ Child C → avoid all DOACs

[GIE @GIE_Journal]

Vanella et al identify "Best practices for EUS-guided gastroenterostomy." https://t.co/yxQWfFPnP6

@GVanell5 @roberto_leone99 @FraFrigo94 @MBronswijkMD @DrLakhtakia @ChahalPrabhleen @AmyTyberg @JovaniManol @MouenKhashab @KBinmoelle35907 @EPerezCuadrado @DouglasAdlerMD

[Endoscopy Journal @endoscopyjrnl]

Editor’s Choice: Multicenter, double-blind, sham endoscopy- controlled, RCT evaluating the efficacy of ARMA for the treatment of GERD

Find the article at: https://t.co/9TwWZ8l5EP
Enrique Rodríguez de Santiago et al.
@DigestivoHRyC
@ESGE_news

[Achintya Singh, MD @AchintyaSinghMD]

A GI numbers pearl:

👉 1 mm = 3 Fr

So:

7 Fr = 2.3 mm
10 Fr = 3.3 mm

A 7 Fr device fits every adult GI scope.

A 10 Fr device needs a ≥3.3 mm working channel (therapeutic gastroscope, adult colonoscope or duodenoscope).

Save yourself a trip to the processor cart.

[Klaus Mönkemüller, MD, PhD @KMonkemuller]

🔪 How to perform a needle knife precut biliary sphincterotomy in 40 seconds

✅ A step-by-step and safe approach - don’t miss the 5 minutes mini lecture on https://t.co/fZqJEZjYJR

🎥 And 500 more videos on anything in GI endoscopy

@theendoscopist @EndoCollabcom

[Andy Tau, MD @DrBloodandGuts]

Behold the “Megacap” ie @OvescoEndoscopy RemOVE FBR Kit.
Remove food bolus en bloc by suctioning rather than pushing blindly inward. The large soft cap allows large volumetric capture and folds to allow for passage down the oropharynx easily.

The long cap prevents the bolus from jamming the suction channel (as it would short caps). When you see “food out, during suctioning, start to wiggle out and reveal your prize!

[UEGJ @UEGJournal]

❄️Cold resection techniques match hot EMR for 10–20mm #SSLs

🔸Cold snare polypectomy(CSP) & cold EMR achieved non-inferior resection vs hot EMR
🔸CSP reduced procedure time
🔸Submucosal injection improved en bloc resection & margin

📖 #OpenAccess 👉 https://t.co/3vi1h7zagC

[Keith Siau @drkeithsiau]

Robotic endoscopy in action! Mounted over the scope, the robot has an arm that is controlled externally, with the ability to rotate, flex and grasp tissue. This enables countertraction to assist with complex resection of neoplastic GI lesions.

[CAG @CanGastroAssn]

📢 2026 McKenna Memorial Lecture on this #JCAGJeudi

📰 Should we screen for colorectal cancer with biennial FIT beginning at age 45 in Canada?

✍️by Linda Rabeneck, Jill Tinmouth, John M Hutchinson, Yibing Ruan, Robert J Hilsden, Matthew T Warkentin, Jennifer J Telford, Harminder Singh, Mark J Dobrow, and others

🔗 https://t.co/i7PfKTLUjx

[Achintya Singh, MD @AchintyaSinghMD]

Identification of liver segments on EUS relies on vascular anatomy: Portal vein & Hepatic vein.

To recognize them:
-Perpendicular to one other ie. if PV is appearing longitudinal, HV will be circular
-Flow on doppler
-Crucial for identification of liver segments

[Eric Topol @EricTopol]

"We health professionals must call urgent attention to this silent but deadly assault [EPA dismantling ] on American's health...."
@NEJM
https://t.co/FJYbZh5O1m

[Dr. Catharine Young @DrCatharineY]

Health agencies should be led by health experts.

National security agencies should be led by national security experts.

Education systems should be guided by educators.

Environmental policy should be led by climate and environmental scientists.

[DWeissLab @DWeissLab]

Bacteria in our BRAINS??!

We observed translocation of bacteria from the gut to the brain via the vagus nerve.

This occurred after high fat diet, or without dietary changes in mouse models of Alzheimer’s, Parkinson’s, and autism.

https://t.co/xfsGN7QLuy

[NEJM @NEJM]

In an international, randomized trial involving patients with acute venous thromboembolism, the risk of clinically relevant bleeding was significantly lower with apixaban than with rivaroxaban during the 3-month treatment period.

Full COBRRA trial results: https://t.co/tvPYrBCWj8

[Giuseppe Vanella @GVanell5]

Distal flange not releasing with Hot #AXIOS?

We prospectivelty observed 12 cases:
❌ Not operator error
❌ Not a broken stent
⚙ Likely a mechanical mismatch

Simple rescue maneuver: “handle springing.”
https://t.co/C5Mwv9IfuV

@endoscopyjrnl
#LAMS #Therapeutic #EUS #endoscopy

[Klaus Mönkemüller, MD, PhD @KMonkemuller]

✅ Classic endoscopic appearance of ileal carcinoid

👁️ Submucosal location, yellow color, smooth surface, vessels on surface

[Keith Siau @drkeithsiau]

Fluid balance within the GI tract 💧💡

📸: Medical Physiology, Saunders 2003

[Sidharth Harindranath MD DM @hsid_h]

Is "asymptomatic" WOPN truly low risk? Our study shows 60% of patients require intervention within 1 year, with a size > 5.6 cm as a key predictor. Vigilant surveillance is 🔑 . @UEGJournal @my_ueg @DeMadaria @pancreatitis_nl https://t.co/9vaiqpgW6W #GITwitter #pancreas #EUS