Pleased to share our new pre-print revealing the mechanism through which G4 RNA binds and inhibits PRC2. Work led by John Houslay, a joint student between our group and the Wilson/Gamblin lab. 1/8
https://t.co/rwoILwffdh
Incredibly happy to share the first publication from our lab, now published in Nature Cell Biology! 🎉
How do cells coordinate RNA processing with nuclear organization and the cell cycle?
https://t.co/Ztg7IA2MWV
1/10
Uncovering the structure-function relationship of a lncRNA critical for genomic stability —still much to learn, but a big step forward! Incredible collaboration with @FMorenoHerrero@OscarLlorcaCNIO@ChillonIsabel & supported by @FundlaCaixa.
Online Now: CONCR lncRNA organizes a 3′-end structural domain that engages DDX11 for DNA replication and sister chromatid cohesion https://t.co/Vmpqvg6o2b
One of the (well, >1) problems in the lncRNA field is that some of the lncRNAs are not real genes, i.e., do not represent a standalone locus that produces independent transcripts. Some cases are more 🤔 than others, e.g. lncDACH that Matt Bennet from @bakergroupcvs dove into 🧵
@Sblancolab@NaldiniLab Yes! It was a fantastic meeting and a wonderful opportunity to catch up with many colleagues and friends, and to see their excellent work. Thanks to Francesco Nicassio @francesconica13 and Monica Ballarino for the invitation!
It was a pleasure and an honor to give a talk at the #SIBBM2026 Annual Meeting! A fantastic conference with outstanding science from speakers like @NaldiniLab, @MaiteHuarteLab, and Luca Pandolfini. Great time meeting old friends and making new ones! 🧬✨
La investigadora @zabaleta_nerea
ha sido elegida académica de número de la
@academia_joven por sus aportaciones científicas en el ámbito de la terapia génica.
https://t.co/qErbQf27IX
New from the lab: melanocytic lineage–specific #lncRNA interacts with the DDR machinery. Its loss in dedifferentiated #melanoma revealed that these cells repair damage better and are thus sensitive to #Olaparib! 💡
https://t.co/d5LGzzx2Zq
El @CIMA_unav obtiene la acreditación como Centro de Excelencia #SeveroOchoa
"Refleja el trabajo y la dedicación de todos los profesionales por generar conocimiento de calidad para mejorar la vida de las personas” José Andrés GómezCantero, director general
https://t.co/wA59xeb8GO
🆕 review with @jp_unfried out in @NatureSMB 🧐. Direct roles of lncRNAs in transcriptional activation. What do we understand about how lncRNAs lure Pol2 and set the stage for RNA production, and what do we still miss? https://t.co/iYJQ7Rbb9d
🚀 Excited to share SMART-PTA (miniaturized Primary Template Amplification) a high-throughput single-cell whole-genome amplification method that preserves clonal lineage information while enabling deep genomic and transcriptomic profiling. https://t.co/xc9qCDG5OF #SingleCell#WGS
It’s been a privilege to be part of the 2025 #HealthResearchMeeting. Grateful to @CaixaResearch for supporting our work on uncovering the structural determinants of long non-coding RNAs involved in colorectal cancer development together with @LlorcaLab and @MaiteHuarteLab