MalDA Consortium

The Malaria Drug Accelerator (MalDA) is a consortium of labs funded by the Bill & Melinda Gates Foundation to accelerate the development of antimalarial drugs.

[MalDA Consortium @MalariaTargetID]

Out today in @CellChemBiol: genetic and chemical validation of PfAcAS as a druggable antimalarial target. Congratulations to all MalDA members on this colossal effort advancing #drugdiscovery in #malaria!

https://t.co/GmPDyw7iyF

[Trends in Parasitology @TrendsParasitol]

One of the cover stories of our June issue https://t.co/cbi2BSoKXJ: #MalDA, Accelerating Malaria Drug Discovery @MalariaTargetID @ElizabethWinze1 @baragana_b @Kelly_Chibale @LlinasLab @fidocklab @UCSDMedSchool @HarvardChanSPH @DDU_Dundee @WUSTL @GSK @MIT

https://t.co/uf3q8jB7XK

[Trends in Parasitology @TrendsParasitol]

Today is #WorldMalariaDay

MalDA, Accelerating #Malaria Drug Discovery @MalariaTargetID @ElizabethWinze1 @baragana_b @Kelly_Chibale @LlinasLab @fidocklab @UCSDMedSchool @HarvardChanSPH @DDU_Dundee @ColumbiaMed @GSK @theGHDDI @sangerinstitute @MITdeptofBE

https://t.co/uf3q8jB7XK

[Winzeler Lab @WinzelerLabUCSD]

Hot off the press! We have identified and characterized MFR3, a novel multidrug resistance mediator in P. falciparum. Read all about it in @ACS_Infectious:

https://t.co/sGlOeaPdVk

[Winzeler Lab @WinzelerLabUCSD]

Out now in @TrendsParasitol: Learn all about how the Malaria Drug Accelerator facilitates rapid #drugdiscovery through collaboration. Featuring the work of multiple Winzeler Lab members and all of our wonderful colleagues in @MalariaTargetID!

https://t.co/BHydURW26B

[Trends in Parasitology @TrendsParasitol]

Malaria Drug Accelerator #MalDA @MalariaTargetID review their achievements & future directions @ElizabethWinze1 @baragana_b @Kelly_Chibale @LlinasLab @fidocklab @UCSDMedSchool @HarvardChanSPH @DDU_Dundee @ColumbiaMed @theGHDDI @sangerinstitute @MITdeptofBE https://t.co/9VKJVraO29

[MalDA Consortium @MalariaTargetID]

New review out now! Find out who we are and what we do in #malaria drug discovery: https://t.co/YxWztAfJMd

[The Fidock Lab @fidocklab]

Looking to recruit a molecular biologist as a postdoc to our lab to work on Plasmodium falciparum drug resistance and drug modes of action. To join a vibrant team at the Columbia university medical center in New York, working closely with @MedsforMalaria and @MalariaTargetID

[MalDA Consortium @MalariaTargetID]

Congratulations to MalDA member @fidocklab on this wonderful and well-deserved accomplishment!

[Medicines for Malaria Venture (MMV) @MedsforMalaria]

Congratulations Dr. David Fidock and team for winning the MMV Project of the Year 2020 Award 👏

Over the past decade, this team has contributed significantly to MMV's portfolio and our efforts against antimalarial resistance.

Read more: https://t.co/uqRZutNgKl

[The Fidock Lab @fidocklab]

Looking forward to @ElizabethWinze1 giving the Craig Lecture this morning at the Alan Magill Sumposium today at #TropMed20. Superb scientist leading the @MalariaTargetID consortium funded by @gatesfoundation

[MalDA Consortium @MalariaTargetID]

Excited for the start of #MPM2020! Congratulations to all of the presenters, which include multiple Malaria Drug Accelerator members.

[MalDA Consortium @MalariaTargetID]

Great work by several MalDA members and collaborators showing that a rapamycin analog targets #Plasmodium FKBP35. Out now in @ACSMedChemLett!

https://t.co/a4olGjZhEW

[MalDA Consortium @MalariaTargetID]

Congratulations to MalDA member Ian Gilbert on this wonderful accomplishment!

[WCAIR Univ of Dundee @WCAIRDundee]

Congratulations Prof Ian Gilbert, Head Medicinal Chemistry @DDU_Dundee #BCDD @UoDLifeSciences.Elected Fellow Royal Society Edinburgh @news_RSE for outstanding research #drugdiscovery #beatNTDS #malariamustdie. Read more https://t.co/VOzzwllarA @MedsforMalaria @DNDi @wellcometrust

[MalDA Consortium @MalariaTargetID]

Need some reading material for the weekend?

Check out this recent paper identifying serine hydrolases as druggable targets in #Plasmodium. Great work from MalDA affiliate labs and collaborators!

[The Fidock Lab @fidocklab]

Excited to share our latest collaboration with @eunayoo and @mbogyo! Check it out:
https://t.co/ZXhKFx6V5v

[WEHI (Walter and Eliza Hall Institute) @WEHI_research]

A new drug target for stopping the spread of malaria has been found after a @CellReports study led by @DrBoddey blocked Plasmodium falciparum from completing the ‘transmission stage’ of its lifecycle. In collaboration with @Griffith_Uni

https://t.co/FXPnH3VwG5

[Trevor Mundel @trevormundel]

For the first time, global efforts are preventing almost 100 million cases of #malaria every year. 🙌

This is great news, but @WHO's report shows that the decline in cases & deaths has slowed significantly. We must accelerate progress to #EndMalaria. https://t.co/bWVQVvZr6u

[MalDA Consortium @MalariaTargetID]

Out now in @CellChemBiol: "Combining Stage Specificity and Metabolomic Profiling to Advance Antimalarial Drug Discovery."

Great work by MalDA team members including @LlinasLab & @WinzelerLabUCSD, spearheaded by @fidocklab's @MurithiJamesM!

https://t.co/aWyngwECqT

[MalDA Consortium @MalariaTargetID]

Check out this @biorxivpreprint article on genome engineering in #malaria parasites from a MALDA member lab! The AT-rich P. falciparum genome is extremely challenging to manipulate, so this is some truly exciting work from Jacquin Niles' group at @MIT!

https://t.co/agQPUb4bYN

[MalDA Consortium @MalariaTargetID]

With our latest MalDA meeting coming to an end, we would like to celebrate all of the hardworking #malaria researchers that make this collaboration so successful. Thanks for the insightful discussions and great #science!

[MalDA Consortium @MalariaTargetID]

Check out this study by MALDA member labs!

[MalDA Consortium @MalariaTargetID]

In vitro selection predicts malaria parasite resistance to dihydroorotate dehydrogenase inhibitors in a mouse infection model https://t.co/2eb3CZjK7q