MANISH KUMAR SINGH

Postdoctoral Fellow @ National Institute of Health

[MANISH KUMAR SINGH @Manish_nih]

@elonmuskOmof 10

[Kotaro Nakanishi @ktr_nakanishi]

We're hiring! Join the Nakanishi Lab at The Ohio State University as a Postdoctoral Scholar. Seeking candidates with experience in protein expression/purification (baculovirus or human cells). Cryo-EM experience is a plus.

Apply: https://t.co/lkqAEgwonx

[Shiv Grewal @grewalsh]

Introns have a hidden regulatory role! 🧬🎉
Delighted to share our latest paper showing that inefficiently spliced introns and spliceosomal proteins direct RNA methylation, engaging RNAi to silence retrotransposons and regulate gene expression
https://t.co/tVTWTewauk

[Biopatrika @biopatrika]

🦴How do bones maintain their delicate balance?
#ResearcherSpotlight @Kshitizwalia @gk_khunger
@arya_subhash from Prof. Amit Tuli @amit_tuli lab at IMTECH @CSIR_IMTECH discuss about "The Bone Balancing Act: Decoding Osteoclasts" @ASCBiology
#bone

[News from Science @NewsfromScience]

Today RNA may seem overshadowed by its glamorous cousin DNA, but many scientists think RNA molecules were the star players in the origin of life. By both storing genetic information and copying themselves, they might have touched off the march of evolution that produced increasingly complex life forms.

So far, researchers haven’t found RNAs that can replicate themselves, a key feature of living things. But they now have something close.

In a new paper, researchers report creating RNAs that can generate a sort of mirror image of themselves and use that template to generate the original. Learn more: https://t.co/lYjYdSD8X5

[Kotaro Nakanishi @ktr_nakanishi]

Functional microRNA targeting without seed pairing | Nucleic Acids Research | Oxford Academic https://t.co/eDLBBHcBHU

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

[MANISH KUMAR SINGH @Manish_nih]

@Chauhanlab_ILS @embojournal @CSIR_IND @ccmb_csir @bric_ils @ANRFIndia @ICMRDELHI Congratulations, She is rising star

[Keith Siau @drkeithsiau]

Noted in a patient with anaemia. What’s the diagnosis?

[MANISH KUMAR SINGH @Manish_nih]

@Chauhanlab_ILS @embojournal Congratulations , wonderful study🍾🎉

[Santosh Chauhan @Chauhanlab_ILS]

FROM CELL DEATH TO REGENERATION: What if dying cells -come back to life? Now online @embojournal I https://t.co/eOKTg6qVnk , we aim to answer this question. Here is the journey. If you🩷science, please dont 🛑till the end of 🧵, I promise you will not regret. 1/n

[The Journal of Immunology @J_Immunol]

Scientists investigated the role of thymic stromal lymphopoietin (TSLP) in #endometriosis, finding that TSLP modulated the endometriotic lesion microenvironment and promoted a Th2 immune response that supported lesion development. Read more: https://t.co/ncl3hKJrci.

[Institut Européen de Chimie et Biologie @iecb_bordeaux]

We are recruiting 🤩🤩🤩!!! If you are looking to establish your lab in a multidisciplinary institute with state-of-the-art facilities, horizontal structure and diverse faculty, all in a near-paradisiac city in the south-west of France, you have 6 weeks left to apply🤓!!!

[MANISH KUMAR SINGH @Manish_nih]

@Chauhanlab_ILS Hoping no more this time...

[Kotaro Nakanishi @ktr_nakanishi]

Chasing non-existent “microRNAs” in cancer | Oncogenesis https://t.co/2no3gDVtuB

[Nico Gagelmann @NicoGagelmann]

Let's learn hematology in 2025🩸

Day 12: diseases and antigens, simplified

[Alessandro Palombo @thealepalombo]

This is India:

- 11% of Fortune 500 CEOs
- 90+ unicorn founders are Indian-born
- 1/3 of all engineers in Silicon Valley are from India

Why have they all left India to succeed?

Here's the hidden truth about the world's most controversial brain drain 🧵:

[MANISH KUMAR SINGH @Manish_nih]

A landmark study showing TF binds and transcribe heterochromatin region. Congratulations @grewalsh @SrivastavManjit and all other coauthors.

[Shiv Grewal @grewalsh]

🔬 Decoding Silencing: How Heterochromatin Transcribes to Silence Itself!
🧬Our latest research reveals how a pioneer transcription factor-like complex PhpC/NF-Y infiltrates repressive heterochromatin, generating transcripts with hidden introns that kickstart RNAi-mediated heterochromatin formation
https://t.co/LMzKtyhlPu

[Fabian Theis @fabian_theis]

Interested in recording cell dynamics? Beautiful review from colleagues around Tanja Stadler and Martin Tran @NatureRevGenet on DNA recording in single cells and lienages. With lots of exciting opportunities for single cell modeling. https://t.co/Xod0Dx9Sk2

[CSIR-IMTech @CSIR_IMTECH]

A special scientific lecture on 'Role of small RNAs in development and disease' is being organized today at 11 am in seminar hall. The lecture will be delivered by Dr. Manish Kumar, Postdoctoral Fellow, National Cancer Institute of Health, Maryland. All are invited to attend.