Marc Forrest

Research Assistant Professor @NUFeinbergMed @NorthwesternU @Penzes_Lab. Interested in genetics and neurobiology of autism, schizophrenia and epilepsy.

[Neuron @NeuroCellPress]

Online now: Soluble α2δ-1, altered in disease CSF, modulates network homeostasis and rescues deficits in a neuropsychiatric mouse model https://t.co/UhoJC3sxGc

[Marc Forrest @MarcForrest7]

Congrats to @MarcDosSantos3 for his incredible work on developing a potentially new therapeutic for schizophrenia. Fortunate to have been part of this work.

https://t.co/kGvbXYIm7D

[Northwestern Autism & Neurodevelopment @NUAutism]

Congrats to @MarcForrest7 , Ph.D., on receiving a 2025 BBRF Young Investigator Grant for innovative mental health research.
Read more: https://t.co/YpPgUFslJc

[Bryan Song @bryanjsong]

Akap11 mutations greatly increase risk for #bipolar disorder and #schizophrenia. Not much was known about this gene when we started. Here’s what we learned!

https://t.co/nCeX4r8ucA

Thanks to Morgan Sheng, @ajgrange, Yang Ge, Borislav Dejanovic & crew @broadinstitute

[Penzeslab @Penzes_Lab]

Come see new work from penzes lab members #sfn2024. Saturday afternoon "synapses", poster session B.

Jessica Christiansen on novel regulatory sites in schizophrenia risk gene TRIO - poster B67.

@MarcForrest7 on homeostatic plasticity in 16p11.2 duplication - poster B68.

[Nature Portfolio @NaturePortfolio]

A Review in @NatRevNeurosci describes our current understanding of the complex genetic architecture of schizophrenia and considers how the genomic findings can be interrogated to boost our understanding of the neurobiology of the disorder. 🔒 https://t.co/O8oaptumsY

[Cell Reports @CellReports]

Five autism-associated transcriptional regulators target shared loci proximal to brain-expressed genes https://t.co/Sbdsu2vrie

[Northwestern Feinberg School of Medicine @NUFeinbergMed]

Northwestern Medicine scientists have been awarded a $17 million grant to study genetic causes of #autism and #schizophrenia, with the aim of developing new drugs to treat the conditions.
https://t.co/XuvmAsblnV

[Veera Rajagopal  @doctorveera]

Whole brain(!) in vivo gene editing to correct a point mutation in a ASD mice model.
Li, Zhang, et al. Nat Neuro
https://t.co/wFPTa9np5l

[Kevin Mitchell @WiringTheBrain]

Very good to see this very large study countering strong claims that maternal infection increases risk of autism in offspring. They found no evidence of an association.

[Veera Rajagopal  @doctorveera]

Glad to see the psychiatric genetics researchers introducing the practice of adding polygenic score effect sizes in the MAF vs effect size plot
https://t.co/biWvB8SYyL

[Veera Rajagopal  @doctorveera]

Nice plot visualizing the effect sizes (vs carrier frequency) of common variants, rare variants, CNVs and polygenic score (top vs bottom decile) associated with ADHD.
From a new Nat Rev Dis Primer on ADHD by Faraone et al.
https://t.co/L9LnN6jbBx

[Ardem Patapoutian @ardemp]

I wrote down my rules on how to Science. I hope you find it useful!

[Marc Forrest @MarcForrest7]

Essay from a medical student suffering from bipolar disorder: "It left me wondering if society has the wrong idea [...] Yes, it may enhance aspects of creativity and productivity at times, but that does not detract from the struggle of living with a chronic illness."

[allen institute @AllenInstitute]

The first cellular map of a mammalian brain is here. 🧠✨

Over 6 years and 32 million cells in the making, the complete adult mouse brain cell-type atlas reveals astonishing diversity and regional specificity.

Dive deeper: https://t.co/CXEIXooOVu

@nature #studyBRAIN #BICCN

[Marc Forrest @MarcForrest7]

New Center for Psychiatric Neuroscience being created at @NUFeinbergMed. Even got mentioned in the new release! 😁

[Northwestern Feinberg School of Medicine @NUFeinbergMed]

We're diving into mysteries of the mind. 🧠

Our newly launched Center for #PsychiatricNeuroscience is breaking down barriers and uniting scientists across disciplines to unravel the complexities of #MentalHealth.

https://t.co/cWIZGKLaDP

[Katie Langin @k_langin]

An NIH advisory group announced today that they're recommending the agency boost its minimum #postdoc salary to $70,000, up from the current $56,484. Many postdocs feel "underpaid and overworked," a co-chair said.

My latest for @ScienceInsider:
https://t.co/NHga0cMAvT

[Vikaas Sohal @sohallab]

A new review summarizing my current thoughts on the neurobiology of schizophrenia: https://t.co/m4QwmyerKo

[⚡️GREG_CORDER⚡️ @FlyBottleEscape]

Just a reminder that Cellpose2.0 is a great, free, fast option to quant all kinds of histology from immediate early genes to RNAscope etc.

Counted cFos for n=12 mice across n=19 brain regions, totaling over 20k cells in ~2hrs

https://t.co/xXyy7Yl8zj

[Veera Rajagopal  @doctorveera]

AI reviewing GWAS literature. Looks pretty cool. May be its time for me to retire. 😅
https://t.co/GIHr8yag4r