Marie Hu, MD

Hematologist/assistant prof @UMNHOT focusing on lymphoma and cell therapy. @MayoMN_IMRes, @OhioStateMed, and @MIT grad. Also foodie and traveler. Tweets my own.

[Marie Hu, MD @MarieHuMD]

Our lymphoma group at #ASH25! #womeninlymphoma

[Supriya Gupta, MD @SupriyaGuptaMD]

UMN ladies of Lymphoma @UMNews @UMNHOT

[Marie Hu, MD @MarieHuMD]

3rd Rock the Vote case at #PPLC24: 65 yo fit M with stage IVA mantle cell lymphoma, MIPI high risk, Ki67 30%, no del 17p or TP53 mutation. BTKi + chemo takes the win. Excellent presentations by everyone!

[Marie Hu, MD @MarieHuMD]

2nd Rock the Vote case at #PPLC24: 61 yo M with usual comorbidities, stage IVB DLBCL (BM involvement), GCB-subtype, IPI 3, MYC/BCL6 rearrangements (no longer considered double hit in WHO 5 but provisional in ICC 2022). Pola-R-CHP wins the round.

[Marie Hu, MD @MarieHuMD]

Loving these Rock the Vote debates at #PPLC24 on controversial first line lymphoma treatments. First case was 22 yo F with stage IVB cHL, IPS 3. Dr. Herrera made a fantastic case for Nivo-AVD (78.7% agreed).

[Andrew M. Evens, DO, MBA, MSc @DrAEvens]

👏👏 Super kudos to @UMNCancer Dr. Bachanova for leading this #HL clinical trial for the @BigTenCRC (together w/ @UIowaCancer Dr Farooq & @UWCarbone Dr Kenkere).

🎇🎇Amazing translational science.

➡️The Big 10 CRC #lymphoma team is just getting started! https://t.co/ou6PxcEVkx

[Marie Hu, MD @MarieHuMD]

@MazieTsangMD @DrRaulCordoba 🙋‍♀️ I’m interested!!

[Marie Hu, MD @MarieHuMD]

Conference views don’t get much better than this 😊 so excited to be at my first (of hopefully many) Luganos! #17icml #lysm

[Marie Hu, MD @MarieHuMD]

Amazing keynote lecture at the ICML-ESMO Lymphoma Workshop on the history and future of lymphoma staging and response assessment by the legendary Dr. Cheson himself!! 🤩 Looking forward to the Lugano 2.0 classification! #17ICML #lymsm @icmlugano

[Joan D. Beckman @jd_beckman]

Excited that @UMNHOT @UMN_DOMResearch @umnmedschool @UMNCancer has been honored with @ASH_hematology hematology focused fellowship! Excited to train fellows in classical hematology in the clinic, wards, and labs!

[Marie Hu, MD @MarieHuMD]

Exciting news! Seems auspicious that we just covered ZUMA-7 in our heme-onc journal club today 😅

[FDA Oncology @FDAOncology]

FDA approved axicabtagene ciloleucel (Yescarta, Kite Pharma, Inc.) for adult patients with large B-cell lymphoma refractory to 1st line chemoimmunotherapy or relapses within 12 months of 1st line chemoimmunotherapy.
https://t.co/IqsjkCk82X

[Toby Eyre @tobyeyre82]

POLARIX PFS subgroup analysis in supplementary of @NEJM Well worth a look!
IPI 3-5 vs IPI 2 differences fairly striking.
#ASH21 #lymsm #DLBCL

[Matthew Cheung @MattCheungMD]

Where are we after 20 years of R-CHOP in DLBCL?

Update from #ASH21 with the POLARIX trial demonstrating a PFS benefit with pola-R-CHP vs R-CHOP (HR 0.73; p<0.02) but no difference in OS. #lymsm

[Marie Hu, MD @MarieHuMD]

Great study which we @UMNHOT contributed to.

Overall 2-year PFS 51% and OS 68%, with no difference in outcomes between R-CHOP vs R-EPOCH as 1st-line tx. Highlights the need for more prospective data and better treatment strategies!

#ASH21 #lymsm

[Graham Collins @graham74GC]

Zayac - HBGL-NOS characteristics & outcomes
- 126, med age 64
- Age-adjusted IPI, stage, EN sites prognostic
- in whole cohort, no diff R-CHOP / DA-EPOCH-R
- de novo BL-like, DA-EPOCH assoc with ⬆️ PFS but not OS (also small group)
Rare and difficult group.
#ASH21 #lymsm

[Toby Eyre @tobyeyre82]

.@mattwilson2287 showing that intercalated HDMTX does not result in lower CNS relapses than EOT HDMTX in 1384 pts.

Valuable data in the selective pts that may still be considered for HDMTX

Great work.
Huge collaborative international effort!
#DLBCL #ASH21 #lymsm

[Marie Hu, MD @MarieHuMD]

Check out our poster (#1832) looking at predictors of relapse after auto transplant for DLBCL! Collaboration between @UMNHOT and @WUSTLmed 😊 @dgermain21

#ASH21 #lymsm #bmtsm

[Marie Hu, MD @MarieHuMD]

Nap pods 2.0 at ASH Central! (if you can find it 😅)

#ASH21 #gettingmystepsin

[Graham Collins @graham74GC]

Bachanova - ruxolitinib + nivo for PD1i failure R/R #Hodgkin
- PI/II dose-esc study
- 19 pts med age 38
- Rux 20mg bd MTD
- 3 reversible immune-rel tox
- ORR 75%; CRR 16%; DOR 12.5mo, 1y PFS 64%
Jak2 inhib may rescue PD1 failures. Interesting combo!
#ASH21 #lymsm

[Marie Hu, MD @MarieHuMD]

We just saw very impressive efficacy of mosunetuzumab in R/R FL, now glofitamab in this bispecific oral session! ORR 81% as monotherapy and 100% in combination with obinutuzumab in pts with median 3 lines of prior therapy.

CRS 79% in the combo group, all G1/2.

#ASH21 #lymsm

[Marie Hu, MD @MarieHuMD]

On my way to ASH
Escaped the MN snowstorm ❄️
Time to learn a lot! 🤓

#ASHaiku #ASH21

[ASH @ASH_hematology]

#ASHaiku is here
Be poetic about ASH
For us to retweet

#ASH21 🎉

[Eric Topol @EricTopol]

Just published @NEJM
A striking 90% reduction in death for booster shots (vs not receiving the 3rd shot) among over 840,000 people, age 50 or older
https://t.co/W22vriA1Se