Mario Leonardo Squadrito

Project Leader at Sr-Tiget, IRCCS San Raffaele Scientific Institute

[ACIR @ACIR_org]

Local tumoral delivery of IFNα by macrophages  @AIRC_it  @Mariosqua. Read our summary here 👉 https://t.co/UD8qAUiGGf

[Mario Leonardo Squadrito @Mariosqua]

@OstuniLab @Nature Well done!! 👏

[Cancer Cell @Cancer_Cell]

Online Now: In vivo macrophage engineering reshapes the tumor microenvironment leading to eradication of liver metastases https://t.co/1FwlPF5fLB

[Mario Leonardo Squadrito @Mariosqua]

@anastasiaconti5 @Cancer_Cell @SanRaffaeleMI @AIRC_it Thanks!!

[Mario Leonardo Squadrito @Mariosqua]

Our work has been published in @Cancer_Cell
Thanks everyone!

@SanRaffaeleMI
@AIRC_it
#GeneTherapy
#Immunotherapy

In vivo macrophage engineering reshapes the tumor microenvironment leading to eradication of liver metastases: Cancer Cell https://t.co/FQDwR9utLt

[Mario Leonardo Squadrito @Mariosqua]

@DiMiccoLab @Cancer_Cell @SanRaffaeleMI @AIRC_it Thanks!!

[Mario Leonardo Squadrito @Mariosqua]

@CasiratiG Congrats 🍾🎉 very nice work

[Cancer Cell @Cancer_Cell]

Online Now: Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer https://t.co/lIjEeVeeV8

[Tirosh Lab @TiroshLab]

1. Excited to share our new paper in @Nature! With over 1000 tumors analyzed by scRNA-seq, we provide a systematic pan-cancer characterization of transcriptional intra-tumor heterogeneity (ITH)
https://t.co/u1aHEatzVz

[Cancer Cell @Cancer_Cell]

Online Now: Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity https://t.co/xFUlHu3F7k

[Mario Leonardo Squadrito @Mariosqua]

Ifnα “helps” immune presentation and T cell activation https://t.co/QjkX8rNwRo

[Mario Leonardo Squadrito @Mariosqua]

Adaptive mutability of colorectal cancers in response to targeted therapies https://t.co/cw54WPpyZd