Renato Ostuni

Ultra-Professor at San Raffaele Institute, Milan. Immunity, Cancer, Genomics, Gene Therapy, and Ultra-Running. Here and "there" at

[Renato Ostuni @OstuniLab]

Super excited about this @czi @biohub grant to develop next-gen myeloid therapies for cancer!
This grant gives momentum to the science that will keep my lab busy for the next decade. Get in touch if you want to be part of the journey 🛫 🎯

https://t.co/lYc6jTiICI

[Ivan Zanoni @Lo_Zanzi]

#InterferonPower! #InflammasomePower! 💥With @kjena21 &co we show @NatImmunol that our fungal adjuvant #Mannadjuvant, via IL1 & IFNs, prolongs & potentiates protection of #mRNA #vaccines, broadening it to new variants & overcoming antigenic imprinting! 👉 https://t.co/G5BxPDMRKW

[Iannacone Lab @iannaconelab]

Neutralizing antibodies are not the whole story. In @NatRevImmunol, we highlight an alternative mode of protection: T cells can eliminate infection at its earliest stage, before it becomes detectable. We term this “abortive infection”
https://t.co/omOjotwLxZ
Thread 1/4

[Renato Ostuni @OstuniLab]

@DrShrutiNaik Wow, super interesting! Congrats Shruti and team 👏

[Renato Ostuni @OstuniLab]

Direct link to our Insight: https://t.co/QeA4bdP2vQ

[Renato Ostuni @OstuniLab]

A great study by the Hoffmann lab in @JExpMed shows innate immune memory can be propagated in a cell-extrinsic way via local cytokine trapping. In our Insight, Luca Frosio and I discuss how these findings suggest spatial niche-specific contron of trained immunity 🎯

[Journal of Experimental Medicine @JExpMed]

Insights: Frosio and Ostuni @MyUniSR discuss study by Gorin et al. (https://t.co/TpryepG5XM) which reveals an unexpected mechanism by which IFN-γ sustains trained immune states through prolonged signaling driven by cytokine retention at the cell surface. https://t.co/clQERsYiC1

[Renato Ostuni @OstuniLab]

Original paper here: https://t.co/l9z11ro5BI

[Renato Ostuni @OstuniLab]

Of all the things I never expected to see, @SnoopDogg C-walking in my home town #Gallarate beats them all

[Giochi Olimpici™ @giochiolimpici]

Yes, @SnoopDogg torchbearer in #Gallarate 🔥🔥

#MilanoCortina2026 #Olympics #TorchRelay2026

[Casanova Acebes Lab @Casanova_Acebes]

Our lab (together with #pacoreal) is looking for a PhD student to work on asthma immunology and PDAC!
If you have a strong interest in immunology and cancer biology, check out the ad below #PhDPosition #PDAC #Asthma #CancerResearch

[Renato Ostuni @OstuniLab]

@obenaufa Congrats!!!

[Renato Ostuni @OstuniLab]

This is one of the best papers of 2025, a definitive resource to map, visualize and ultimately understand the logic of neutrophils. So happy to see such massive achievement by amazing scientists and human beings @ivanbamartin
@AndrsHidalgo16
@lai9uan
https://t.co/yD5H5FhMph

[Renato Ostuni @OstuniLab]

@AndrsHidalgo16 @niseto Just beautiful, so happy to see it out 👏👏👏

[Renato Ostuni @OstuniLab]

@danielacerezo @niseto @Nature @AndrsHidalgo16 Fantastic paper 🤩

[Renato Ostuni @OstuniLab]

@Alba_dejuan Broccoli power!

[Renato Ostuni @OstuniLab]

@IdoAmitLab @CellCellPress @MVLocquenghien @PascaleZwicky @CuriousKX Congrats Ido and team! Super interesting approach

[Renato Ostuni @OstuniLab]

@DiStefano_Lab @NatureBiotech @Brumbaugh_JB Grande Bruno!!! Congrats to the team 🔥

[Renato Ostuni @OstuniLab]

I am honored to receive the @AIRC_it “Beppe Della Porta” Biennial Award and to meet Italy's President Sergio Mattarella in a deeply moving ceremony @Quirinale Palace. I am grateful to my family, mentors, friends, and the incredible scientists in my lab.
dad, this is for you🩶

[Renato Ostuni @OstuniLab]

Guess I've been unconsciously cutting back energy on many things lately 🤔

[nature @Nature]

When athletes devote large amounts of energy to running or cycling, they unconsciously cut back on energy output elsewhere

https://t.co/BQI522jsPh

[Renato Ostuni @OstuniLab]

@XuZhouLab @jkagan1 @CellCellPress @harvardmed Beautiful paper Xu! MASSIVE congrats to you and the team

[Renato Ostuni @OstuniLab]

My biggest adventure (yet): the Tor Des Geants, one of the hardest ultra-trail races❤️‍🔥. Can't express the mix of happiness, fear & fatigue of running 113 hours (350km, 25K climbing) in the mountains. Even made it in the top 15%! But now.. back to work, cool science is cooking 👨‍🔬