Mark Herman

Dad, scientist, physician, other. Endocrine Chief, Houston, TX. All views and opinions are my own.

[From the Labs at Baylor College of Medicine @BCMFromtheLabs]

Baylor @bcmhouston and associated institutions awarded grant to establish the Houston #Nutrition and #Obesity #Research Center @MarkHermanMD https://t.co/GVEWJfWQjc

[Layla Abushamat @LaylaAbushamat]

Excited to share our analysis showing that erythritol and erythronate may serve as markers of poor cardiometabolic health and cardiovascular outcomes in older adults. @CBallantyneMD @MarkHermanMD @vijay_nambi @ChiadiNdumele
https://t.co/iAJGvh7Bt6

[Charles Brenner, PhD @CharlesMBrenner]

excited to share new work
Glycerol-3-phosphate activates ChREBP, FGF21 transcription and lipogenesis in Citrin Deficiency

led by Vinod Tiwari, Olivia Sun & Edwin Lopez Gonzalez from my lab, Byungchang Jin @russpgoodman lab, @MarkHermanMD & @Cnspracklen

https://t.co/cBkN3l1zsY

[Mark Herman @MarkHermanMD]

Great talk and turnout for Holly Ingraham at the second annual Houston Nutrition and Obesity Research Symposium!

[Mark Herman @MarkHermanMD]

One of the lab's -80 freezers died last night ... samples saved. Happy Halloween! We are in the market for a new one. There were good threads about preferred makes/models in the past but I can't seem to find them. Any recommendations?

[Eric Taylor @Mitoverse]

Have you ever wondered how mitochondrial and cytosolic pathways for de novo lipogenesis (DNL) interact?

We did!

Published Online today (https://t.co/l05A4qyCx1) and led by first-author @adam_rauckhorst, we traced 13C-labeled lactate/pyruvate, acetate, the ketone acetoacetate, and leucine in several mouse models of disrupted hepatic mitochondrial and cytosolic acetyl-CoA generating pathways.

Surprisingly, deleting the mitochondria citrate carrier (CiC) increased DNL from both exogeneous and leucine-generated acetoacetate. Overall, our findings delineate a mitochondrial-cytosolic DNL substrate supply network that may guide more accurate therapeutic development for MASLD and T2D.

Many thanks to our expert collaborators: No X Ryan Sheldon, now leading metabolomics at the @VAInstitute, who helped start the project and develop the necessary mass spec methods with @adam_rauckhorst; for @StanislawDeja and @Isotopomer for deuterium tracing by NMR and careful contibutions to quantitatively framing our mass spec data; and Tom Vallim of @TarlingVallim for guidance with in vivo gene deletion by AAV CRISPRs.

Please also see the exciting co-published manuscript from @WellenLab and Christian Metallo Labs (https://t.co/Wq1JH6AXZS) showing that bempadoic acid does more than just inhibit ACLY!

@FOEDRC, @UIowaResearch, @UIMolecPhysBio

[Eric Topol @EricTopol]

A substantial reduction of #Alzheimers disease associated with semaglutide (Ozempic) in > 1 million people with Type 2 diabetes from a nationwide data resource
https://t.co/0hQlGivUGi

[Alison Cook @alisoncook]

Boom ‼️‼️‼️The Houston Chronicle’s Top 100 Restaurant list is out, with 15 making their first appearance and several old favorites topping the list. https://t.co/uDd6t6VxmW

[Daniel J Drucker @DanielJDrucker]

Among 4,052 adolescents with #obesity who initiated treatment with a GLP1RA, a 33% lower risk of suicidal ideation or attempts after at least 12 months & at up to 3 years of follow-up was observed relative to propensity matched controls @JAMAPediatrics https://t.co/RXhloSf0Gx

[Giulio Superti-Furga @giuliosf]

We are excited to kick off our series of 4 manuscripts from the RESOLUTE consortium by sharing the metabolic mapping of the Solute Carrier Superfamily (https://t.co/OAn581qvIN)!

[Peggy Goodell @Goodell_Lab]

Recruiting faculty to the Dept of Molecular and Cellular Biology at Baylor College of Medicine in Houston, TX! Recruiting broadly in cancer and cell biology. Submit by October 1, 2024, for full review. #cellbio @BCMhouston
https://t.co/4sLzKsOxzD

https://t.co/4Q9xpXvcbI

[From the Labs at Baylor College of Medicine @BCMFromtheLabs]

New #McNairScholar named at Baylor College of Medicine https://t.co/lgEXdqwnpL @bcmhouston @BCMDeptMedicine #neuromodulation

[Daniel J Drucker @DanielJDrucker]

Your regular reminder of the limitations, pitfalls and controls required for accurate use of and interpretation of data with Cre driver lines in mouse metabolic research @NatMetabolism @WolfrumLab https://t.co/WzUQxlbu2K

[BCM Clinician Resources @BCMCME]

Dr. Bahar Force discusses clinical advances in the screening, diagnosis, and surgical treatment of patients with Cushing disease. #CME credit available! https://t.co/sXfaVtnAyS

@bcmhouston @BCMDeptMedicine

[ADA Professional Publications @ADA_Pubs]

The August #DiabetesBio #Podcast is now online!

Topics include: Interviews with Drs. Inbal Caspi, @DanweiHuangfu , and @DeepthiPMallela. Sweet talk with coauthors of recent "Classics in Diabetes" Drs. Bernard Thorens and @daveyboyhod.

🎙️ https://t.co/VOgY9gBVwR

@thewilliamslab @KirkMHabegger @DarleenSandoval

[Rexford S. Ahima, MD, PhD @rex_ahima]

The HuMet Repository: Dynamic metabolomic responses to physiologic tests in healthy adults

https://t.co/o8J6FQ1t3H

[BBQ Bryan @BBQBryan]

The Whataburger app works as a power outage tracker, handy since the electric company doesn't show a map.
Still nearly 1.9 million power outages.

[Mirela Delibegovic @mdelibeg]

Delighted to receive the Royal Warrant signed by FM & His Majesty the King with my appointment as the Regius Chair of Physiology @aberdeenuni. I would like to thank all my colleagues, friends and lab members over the years! @AberdeenCDC @AbdnLifeScience https://t.co/8ppeewdCSx

[Lisal Folsom @DocFolsom]

Taxing sugar sweetened beverages - helpful? Seattle has some data! #taxes #sugar #obesity #BMI @JAMA_current https://t.co/oBpYGg4c26

[The Williams Lab @thewilliamslab]

It's happening today!

Come meet the Podcast team for #DiabetesBio #DiabetesCare #DiabetesCoreUpdate @AmDiabetesAssn #ADASciSessions