We are immunologists at the University of Toronto ๐จ๐ฆ Opinions expressed here reflect @albertoxmartin โs opinions exactly, every single one, without exception.
New paper from the martin lab: Phil Barbulescu and Chetan Chana from the @albertoxmartin
and Frank Sicheri labs published this article showing that FAM72A degrades UNG2 through the GID/CTLH complex to promote mutagenic repair during antibody maturation | Nature Communications
A big congrats to Dr. Yuqing Feng from the @MartinLabUofT for winning the BD Biosciences Postdoctoral award and a huge thanks to @BDandCo for funding the award. Dr. Feng recently published her work on DNA repair in @Nature https://t.co/tY4hMT1uNQ
Very happy to share our latest review article published on @TrendsImmuno today, where we discuss the latest progress on mutagenic DNA repair during antibody diversification in B cells @MartinLabUofT https://t.co/kzQyOpNQhP
Researchers in the lab of @UofTMedicine's Alberto Martin discovered an overlooked gene that plays a major role in the development of antibodies. #UofT ๐ฌ https://t.co/v91Tk3MFbv
Congratulations to Yuqing and Conglei in the lab for their excellent study that was just published in Nature.
https://t.co/urod2yEYgf
And thank you to the many collaborators that helped contribute to this work.
This week we celebrated the farewell of Yann Malaise, a wonderful post-doc in the lab for the past three years. We wish you all the very best for your future endeavours, Yann.
I am looking for a #PostDoctoral Fellow to study B cell biology and the DNA repair pathways that are associated with antibody diversification processes. More information about the position is available here: https://t.co/whp3QJ7j8k
Give this woman a Nobel Prize.
https://t.co/KQrjyvI2ez
UPenn "told me that theyโd had a meeting and concluded that I was not of faculty quality,โ she said. โWhen I told them I was leaving, they laughed at me and said, โBioNTech doesnโt even have a website.โโ
The latest study from our lab is now online @emboreports.
SHLD2 Promotes Class Switch Recombination by Preventing Inactivating Deletions Within the Igh Locus. https://t.co/oo0sWZc8yN
I am excited to launch the weekly Social DNAing webinar series on June 18,2020- a virtual meeting room for the genomic instability community. Check it out as https://t.co/8MUDs14F7c
Marking the 20th anniversary of the discovery of Activation-Induced cytidine Deaminase (AID), we discussed the biochemistry, function and regulation of AID in Antibody Diversification in this new review @TrendsImmuno.
https://t.co/RJbejtFEMq
Our latest study just out @NatureComms by Tey Irrazabal et al. shows limiting oxidative DNA damage reduces microbe induced colitis-associated colorectal cancer.
Latest from the @MartinLabUofT: Study suggests that #IBD patients might benefit from the use of antioxidants or inhibitors of iNOS to blunt the oxidative DNA damage that can precipitate #colitis-associated #ColonCancer. https://t.co/sCIVqMxmgK