MassChallenge

The global network for innovators. Come solve with us.

[MassChallenge @MassChallenge]

Heading to #HLTHUSA next week? Come find MassChallenge at Booth 846!

We're bringing nine startups to our pavilion, with founders working on earlier disease detection, better sleep, care delivery and AI.

Stop by our startup pavilion to see what these founders are building:

#AOADx
#FasciaSleep
#Flourish Care
#Leaf Guardian
#Lexi
@MyBiometry
@SeeInMe_Inc
@trendcommunity
@VironixHealth

If you're a health system, pharma company or industry leader looking for your next innovation partner, come say hello!

📍 HLTH USA | The Venetian, Las Vegas
📅 November 15 to 18, 2026

🔗 https://t.co/bOXd1BDHlm

#MassChallenge #HLTHUSA #HealthInnovation #Startups

[MassChallenge @MassChallenge]

The real test of security & resiliency technology is what happens when everything around it stops working.

Meet our 2026 Security & Resiliency Traction cohort: 39 dual-use startups, from the ocean floor to orbit.

https://t.co/u8p5Kp761x

#MassChallenge #DualUseInnovation

[Innovation Nights @MassInno]

Will you have a new robotics or physical AI product to launch in February?

On Feb 10, we will be taking over the NEW Bloomberg Public Science Common at the @MuseumofScience in partnership with @MassRobotics.

Submit your product to be featured today:
https://t.co/sLKjx58iNK

[MassChallenge @MassChallenge]

14 business challenges from enterprise teams including @EliLillyandCo, @massmutual, @TheHartford, and @AltusDental. The deadline to apply to the MC Challenge Program is extended to Mon, Nov 16 @ 11:59 PM ET.

For founders, it’s a chance to work directly with enterprise teams on a defined business need.

Have questions about fit, the process, or what to expect? Join our live info session this Friday, November 13 at 9:30 AM ET.

🔗 Learn more, apply, or register for the info session: https://t.co/wXyVG70jmB

#MassChallenge #Startups #Innovation

[MassChallenge @MassChallenge]

⏳ Applications close Monday, November 9!

This cycle of the MC Challenge Program features 14 challenges spanning AI-powered fraud prevention, preventive health, property risk intelligence, next-generation computing, and more.

Enterprise partners including @EliLillyandCo, @massmutual, @TheHartford, and @AltusDental have defined the problems. Now they're looking for founders building the solutions.

Building in these spaces? See where your startup fits and apply now. Initial applications take less than 10 minutes!

🔗 https://t.co/wXyVG70jmB

#MassChallenge #Startups #Founders #EnterpriseInnovation #HealthTechInnovation #FinTechInnovation

[MassChallenge @MassChallenge]

Standing room only in Boston! 🙌

Our Dual-Use Symposium is underway, connecting founders, government leaders and industry experts advancing technologies across commercial and defense markets.

A huge thank you to our sponsors for making today possible: @CanadaGovRBX, @Raytheon, @BAESystemsInc, @FidelityPrivate, @FoleyHoag, @jpmorgan, @MITREcorp, @PTC, and @MassCEC.

Stay tuned - more highlights to come! #DualUse #MassChallenge

[MassChallenge @MassChallenge]

The right environment can change what’s possible for a startup.

MassChallenge is accepting applications for a select number of startup residencies at our new 401 Park headquarters in Boston’s Fenway.

96 desks. One-year residencies starting January 2027.

Spaces are limited. Apply by November 30: https://t.co/PeY1F0eAwN

#MassChallenge #BostonStartups #Founders #BostonInnovation

[MassChallenge @MassChallenge]

Could your startup solve a real enterprise challenge?

Explore opportunities with companies including @EliLillyandCo, @TheHartford, @massmutual and @AltusDental.

📅 Live info session: Nov 3 @ 1 PM ET

Explore challenges & register: https://t.co/Ucmyinzrqe

[MassChallenge @MassChallenge]

BIG THINGS HAVE TO START SOMEWHERE.

The @SMUCox FinTech Accelerator powered by MassChallenge is the first step in a planned fintech coalition and is open to startups from around the world.

Join our live info session to learn about the inaugural cohort.

📅 Nov 2 | 2:30 PM CT

https://t.co/tBQvKuF0xn

#MassChallenge #StartUps #Founders #SMUCox #FinTech

[MassChallenge @MassChallenge]

@marshsutherland Now THAT would make for a popular cohort activity. We'd happily tag along! ⚾

[MassChallenge @MassChallenge]

MassChallenge is moving to the Fenway!

After 15+ years helping shape Boston’s Seaport innovation community, we’re bringing that same ambition to 401 Park, our new global headquarters in Alexandria Real Estate Equities Inc. Megacampus™.

Our new home will connect founders, corporate partners, investors, and ecosystem leaders, with select space available for entrepreneurs looking to build and grow in Boston.

Read the full announcement and explore opportunities at 401 Park:
https://t.co/e1kmicVQ9g

#MassChallenge #BostonInnovation #Fenway #Seaport #Startups #Entrepreneurship

[MassChallenge @MassChallenge]

From the Seaport to the Fenway, MassChallenge is preparing for its next chapter in Boston.

In a new @BostonGlobe story, @jonchesto explores our move to the Fenway, our role in shaping the Seaport's Innovation District, and what it means to leave the neighborhood where we got our start.

The story also looks at our partnership with Alexandria Real Estate Equities, Inc., how MassChallenge has evolved since 2009, and CEO Cait Brumme's vision to double our reach by 2030.

As Chief of Staff Robby Bitting tells the Globe, Boston's momentum is undeniable, and we're looking forward to contributing to what's happening in the Fenway.

Thanks to Jon for telling the story.

🔗https://t.co/YuNALduCNQ via @BostonGlobe

#MassChallenge #BostonInnovation #Startups

[MassChallenge @MassChallenge]

@Defi_Warhol @ycombinator @speedrun @sequoia @pearvc Thanks for the mention @Defi_Warhol!

[MassChallenge @MassChallenge]

Last chance to apply for the
@sanofi THRIVE Challenge! Applications close tonight.

Some health problems are harder to solve because of where they happen. That’s exactly why they need people willing to solve them.

We're looking for founders building healthtech and digital health solutions to improve health outcomes in rural and underserved communities, from early-stage ideas to solutions ready to pilot and scale.

If you're building something that could make a difference for patients and communities too often overlooked by healthcare innovation, this is your moment.

Apply now: https://t.co/Rb9hcgmGsT

#HealthTech #DigitalHealth #RuralHealth #Sanofi #MassChallenge #Founders #Startups

[MassChallenge @MassChallenge]

Today, MassChallenge CEO Cait Brumme joins leaders from across Massachusetts' deep tech ecosystem at the Boston Hard Tech Summit, part of Tough Tech Week 2026!

Moderated by Vinit Nijhawan of @massventures, the Mass Leadership Panel brings together Cait, Alicia Barton of @VineyardOFSHR, Rhett Smith of @enginexyz, and Georgina Campbell Flatter of @GreentownLabs for a conversation about the opportunities and challenges facing Massachusetts deep tech startups.

Join the conversation this afternoon!

📍 10 Prospect Street, Somerville, MA
🕝 October 26 | 2:30–3:15 PM ET
🔗 https://t.co/8y5vn688P0

Thanks to Campus Deep Tech and MassVentures for bringing this conversation together.

#ToughTechWeek #DeepTech #HardTech #BostonInnovation #MassChallenge #Startups #Innovation #Founders

[MassChallenge @MassChallenge]

Building in fintech? The @SMUCox FinTech Accelerator, powered by MassChallenge, is open to founders worldwide working in AI, blockchain, cybersecurity, capital markets, and beyond.

⏲️ Applications close soon.

Register for our next virtual info session on Nov. 2 at 2:30 PM CT.

🔗 https://t.co/tBQvKuF0xn

#FinTech #SMUCox #MassChallenge #Founders

[MassChallenge @MassChallenge]

What if #Boston could become the healthiest city in the world?

We were honored to welcome @CityOfBoston Mayor Michelle Wu to this week's Yes/Boston Innovation Challenge Finale & Showcase, where 11 startups shared their plans to connect food innovation with better health outcomes.

Led globally by @wef, Yes/Boston is powered by MassChallenge with support from @AWS, @Citi, and @Deloitte.

The work is just beginning. Learn more and join the coalition: https://t.co/GUguQdA5yJ

📸 Mike Mejia / Boston Mayor's Office

#YesBoston #YesCities

[Ksenia Moskalenko @kseniam0s]

OPPORTUNITY‼️: MassChallenge will put you through a 5 month accelerator, pair you with a corporate partner, and give you mentors.

This is @MassChallenge - global startup accelerator.

What you get:
- a spot in the 26/27 challenge program
- time with a corporate partner on a published challenge
- mentors in marketing, law, investment, compliance and technology
- access to 500+ partners, 3K+ experts
- a kickoff in Boston and a finale showcase in mid-June

Who qualifies: pre-seed to Series A, startups worldwide, with a fit to one of the partners' challenge statements.

Apply by November 9 👉 https://t.co/t6WIEDDDAh

[MassChallenge @MassChallenge]

Big news for the @sanofi THRIVE Challenge!

We're welcoming @NACHC as a collaborator AND extending the application deadline to October 27!

Building healthtech for rural and underserved communities? There's still time to apply.

https://t.co/fBQfDvlIUu