Lynn Megeney

We study the fascinating non-lethal biology of caspase/metacaspase proteases ☠️. We are also interested in the molecular cues that manage cardiac remodeling🫀

[Science News @ScienceNews]

Lung cancer patients who received an mRNA COVID-19 vaccine within a few months of immunotherapy lived nearly twice as long as unvaccinated patients. https://t.co/IeAVXaLdz9

[Stephen L. Archer @DrStephenArcher]

Book signing with Dr Tony Sanfilippo, and his amazing wife Michelle. Tony is the author of “The doctors we need” ⁦@QueensuDOM⁩ ⁦@KingstonHSC⁩ ⁦@queensutime⁩ -a great read on how Canada can solve its doctor shortage problem-a must read!

[Matthew S. Alexander @Matt_Muscle_Guy]

Interesting work from @Rudnicki_Lab in @NatureComms : Intrinsic dysfunction in muscle stem cells lacking dystrophin begins during secondary myogenesis. https://t.co/ncvosY960X

[Lynn Megeney @MegeneyLab]

@DPicketts I would call it a Herculean effort, Nature Genetics should have jumped at it!

[Lynn Megeney @MegeneyLab]

@DPicketts congratulations on a great paper! very cool story

[David Picketts @DPicketts]

Excited to share our paper with Ghayda Mirzaa describing the novel SMARCA1-related NDD. Out today in Nature Communications.
https://t.co/2afKsQLPEH

[Cincinnati Children’s Research @CincyResearch]

We’re proud to celebrate @CincyKidsHeart's Jeff Molkentin, PhD, for receiving @UCincyMedicine's 2025 Daniel Drake Medal—college's highest honor! His groundbreaking work in cardiovascular biology continues to advance science & inspire next-gen researchers: https://t.co/m05nWnU3VG

[Matthew S. Alexander @Matt_Muscle_Guy]

New @NatureComms paper: Alterations in peroxisome-mitochondria interplay in skeletal muscle accelerate muscle dysfunction. https://t.co/6ozfmzKlTk

[Joe Gordon @josephwgordon]

https://t.co/WJ5qGupw0i

[Stephen L. Archer @DrStephenArcher]

Celebrating an amazing trip up Mount Kilimanjaro with daughter Elizabeth, supported by team Ultimate Kilimanjaro ⁦@UltimateKili⁩ @QueensuDOM⁩ ⁦@queensutime⁩ ⁦@KingstonHSC⁩ -19341 feet of challenging, hypoxic beauty. One of the hardest things I’ve ever done!

[Matthew S. Alexander @Matt_Muscle_Guy]

New @NatureComms paper: Large-scale serum protein biomarkers discovery associated with function and clinical milestones in Duchenne muscular dystrophy. #DMD https://t.co/fhhkZ0saar

[Matthew S. Alexander @Matt_Muscle_Guy]

Congrats to @LorsonLab and colleagues for their new @hmg_journal paper: Novel neurofilament light (Nefl) E397K mouse models of Charcot–Marie-tooth type 2E (CMT2E) present early and chronic axonal neuropathy. https://t.co/n5fjsjt1qN

[Lynn Megeney @MegeneyLab]

one of the most interesting papers on muscle biology in decades....a challenge to the satellite cell hypothesis!!!!

Muscle growth by sarcomere divisions | Science Advances https://t.co/H2j3h7a5AL

[Lynn Megeney @MegeneyLab]

@Matt_Muscle_Guy well done!

[Matthew S. Alexander @Matt_Muscle_Guy]

New @NatureMedicine paper: AAV mini-dystrophin gene therapy for Duchenne muscular dystrophy: a phase 1b trial. #DMD https://t.co/1t5ghyvRZV

[Matthew S. Alexander @Matt_Muscle_Guy]

Interesting new #JACC paper: Long-Term Dystrophin Replacement Therapy in Duchenne Muscular Dystrophy Causes Cardiac Inflammation. https://t.co/7x5jMg40nU

[Lynn Megeney @MegeneyLab]

very cool paper from Assaf Vardi's group on metacaspase function in diatoms. Metacaspases mediate thermotolerance of diatoms following marine heat waves | bioRxiv https://t.co/JwxUQ9kRB6

[Natasha Chang @chang_natasha]

Happy to share that our single-cell analysis of muscle stem cells in two DMD models is now published in Cell Death & Disease. We hope this resource benefits researchers in neuromuscular disease and helps to support the development of stem cell targeted therapies for DMD.

[Lynn Megeney @MegeneyLab]

@amacklin10 That was ominous!

[Andrew Macklin-WX @amacklin10]

Huge wall cloud over East Ottawa right now! #onstorm cannot discern rotation