MendjanLab

human cardiogenesis | congenital heart defects
self-organization | bridge molecules-cells-tissues
training a new generation of scientists

[MendjanLab @MendjanLab]

Two years ago, we reported for the first time on #cardioids. Now, our team, led by two fantastic Ph.D. students, Alison and Clara, developed multi-chamber cardioids representing all the major regions of the human embryonic heart (atria, LV, RV, OFT, AVC) https://t.co/fJqE5ErYXU

[Frank Schnorrer @SchnorrerL]

Force regulation of myogenesis by Tono, a BTB-Zn finger transcriptional regulator, which forms droplets after acute high pressure application. It responds in 1 minute :) - in yellow in the nuclei https://t.co/cdbNQwPj3j
Congrats to Xu Zhang and @JrmAvellaneda #Drosophila #muscle

[Rashmi Priya @rashmi-priya.bsky.social @_Priya_R]

Beyond thrilled to present our first (!) work @TheCrick! A tour de force by @tobyandrews et al combining imaging, solid morphometrics, theory, perturbations to show how a developing heart grows and scales up its morphological complexity to keep beating...
https://t.co/RghtQtmYxF

[Matthias Vorländer @MVorlandr]

Very excited to see our new paper online @Nature, where @justuskleifeld @Patricia_Rothe_ and myself decipher the molecular choreography for how disassembly of the spliceosome begins. This was a great collaboration between the @plaschka_lab and @LCochella lab @IMPvienna.

[Rashmi Priya @rashmi-priya.bsky.social @_Priya_R]

'The Mechanics of building functional organs - our take on this fundamental problem. We discuss general design rules building complex 3D geometries, advocate for a holistic understanding of morphogenesis by embracing the complexity of embryonic development.https://t.co/hZyvqxuWgT

[IMBA imbavienna.bsky.social @IMBA_Vienna]

Congratulations to Clara Schmidt, @MendjanLab, who successfully defended her PhD thesis titled “Multi-Chamber Cardioids Unravel Human Heart Development and Cardiac Defects!”

[MendjanLab @MendjanLab]

@hendersi Big congrats, Ian!

[Brian Roemmele @BrianRoemmele]

Meet EcoBot the professional weeder.

The Machine Learning, Solar powered apparatus that can run for the entire day pulling weeds.

Replaces expensive in every possible way, herbicides.

[IMBA imbavienna.bsky.social @IMBA_Vienna]

Elly Tanaka will be IMBA’s new Scientific Director, heading the institute from April 2024 onwards. Elly Tanaka is a renowned researcher, who studies the regeneration of complex body parts. Welcome, Elly!

[IMBA imbavienna.bsky.social @IMBA_Vienna]

New manuscript alert! Writing in @Nature, the Burga Lab (@arburga) describe a genomic silencing mechanism which represses a selfish genetic element in the eggs of the nematode C.tropicalis only when it is paternally inherited. Their findings reveal the potential evolutionary origin of genomic imprinting.
https://t.co/6JLDNaIyNH

[Anton Goloborodko @[email protected] @golobor]

Our paper describing Bioframe, a python library for working with genomic intervals, was just accepted! https://t.co/GxWAf9GeEp

[Rashmi Priya @rashmi-priya.bsky.social @_Priya_R]

What a beautiful sight - children with Microscopes, curiosity in their eyes learning the wonders of Developmental Biology! Terrific outreach event organised by @InSDB_79 and fantastic students at @NCBS_Bangalore. Great start to InSDB 2024!

[Frank Schnorrer @SchnorrerL]

Our new data-driven mathematical model of sarcomere assembly is now out. All the math was done by our fantastic collaborators in Dresden @friedrich_group @PoLDresden @IBDMmarseille @ClaraMSidor @BDehapiot https://t.co/gaaP6lmqTp

[Itai Yanai @ItaiYanai]

What graduate degree should you go for? The MBA, the MD, the JD, or the PhD? The PhD is unique - it has to be said - for teaching both critical reasoning and the creative process of discovery; skills that prepare you for anything you’d then want to do.

[TinaHaase @TinaHaase3]

Our latest release on placental microvasculature..Just in time for the holidays! ⁦@LabHaase⁩ https://t.co/U59AkQzWSH

[Ulrich Technau @UlrichTechnau]

One decade after starting this journey, our collaborative paper with @Gibson_lab is finally out: https://t.co/0o4xuMSEZF.
It reports chromosome assemblies of the related sea anemones @Nematostella and Scolanthus callimorphus. Will be an important resource for the community.

[Dr Naomi Moris @nmoris]

Is there a better way to make PGCs in culture than with disorganised EBs and signalling cocktails? In our latest pub @Dev_journal we show that mouse 'gastruloids' make beautiful PGCs... 😍 [as also seen by others] (1/6) https://t.co/5ysnCYWC8F

[Uri Alon @UriAlonWeizmann]

Why do we get certain diseases whereas others do not exist?
This new book builds a foundation for systems medicine. Starting from basic laws, it derives why hormone, immune and aging circuits are built the way the are, culminating in a periodic table of diseases.

[Andreas Bergthaler ☮️ @abergthaler]

Great study in @CellCellPress from our virologist colleagues @puchhammer et al & neurologists of the @MedUni_Wien. Bravo!! 👏

Specific Epstein-Barr virus determinants and immune responses by NK & T cells implicated in the risk for #multiplesclerosis.

https://t.co/aGYZJbSSHJ

[Anna Osnato @AnnaOsnato]

Cannot recommend this enough!