@robynrdobbins Happy Day 1!
Here to celebrate with you! 💐🥰💐
Baby steps & consistency give our connective tissues time to adjust.
My day 1 back at it as well.
High LDL but Low Blood Pressure 🩸
One reason I might have no detectable soft or calcified coronary plaque (0 mm3), despite my historically astronomical LDL cholesterol (PMID: 42187880), is my low blood pressure.
Here's a bit of biology: Atherosclerosis isn't simply about LDL circulating in the bloodstream then diffusing into the artery wall randomly.
In other words, the endothelium isn't just a passive barrier. And it's exquisitely sensitive to mechanical forces.
In straight arteries, smooth, laminar blood flow generates shear stress that promotes protective pathways, including nitric oxide production and anti-inflammatory signaling.
However, when flow becomes disturbed and/or blood pressure increases, the variation in mechanical forces alter chemical signaling, and very likely transcytosis we all.
So, it’s a reasonable hypothesis to state my low blood pressure is one reason my heart is as clean as a whistle.
🚨 The point: Atherosclerosis isn't just about the LDL particles. It's also about the metabolic environment.
And, here are 6 other factors I care about when evaluating the metabolic environment in which my heart lives.
What do you score?
And have you download the free Beginner’s Guide to Metabolic Health yet?
(Link 🔗 in quoted post👇)
💯% FREE. Not even an email gate.
Share widely!
P.S. I'll be delving into the topics in far more detail in upcoming deep-dive content.
Presley Gerber had every resource in the world. Loving famous parents, access to the best doctors money can buy, lots of people genuinely trying to help him. And a year before he died, he told us all exactly what was wrong, on Instagram:
He'd been through 15 different psychiatrists. All any of them offered was different drugs. Nothing was working. And he was searching for one thing he couldn't find: someone to taper him off.
Shortly after that, another reel: two different benzodiazepines, buprenorphine, and more. A cocktail. And a year later he's dead at a rehab, with the same combination that keeps appearing in these stories: benzodiazepines plus opiates.
I sat down with Dr. Drew to talk about it, because the pattern has become impossible to ignore. Hayden Panettiere's toxicology is now out, per reporting: benzodiazepines, antipsychotics, fentanyl. Matthew Perry. Heath Ledger. Different decades, different famous faces, same cocktail. All the access in the world, and what it bought them was more prescribers, more prescriptions, and no exit.
That's the detail that should haunt everyone: the thing Presley couldn't find in all of Hollywood wasn't another medication. It was a doctor willing to help him come off. Deprescribing is the rarest specialty in American medicine, and people are dying in the gap.
Hollywood organizes around so many causes. The cocktail of sedatives and opiates is killing their friends and their children year after year, and it should be their number one issue. The silence tells you how completely the "this is just modern medicine" story has won.
Full conversation at the link in bio.
If you or someone you love is struggling, SAMHSA's free helpline is 1-800-662-4357. If someone you know takes both a benzodiazepine and an opioid, talk to their doctor now, and ask about naloxone.
If you're looking to safely taper off a psychiatric medication, comment TAPER and I'll send you my free tapering guide. It's the exact protocol we use with our patients at TaperClinic.
Never stop these medications abruptly. Any taper should be gradual and medically supervised.
We just had a resident move back into on of our assisted living homes after he moved back home about a year ago.
Back then we improved his A1C from about 12 to 5.8, lowered his blood pressure and had him walking well. 🧵(1/8)
Here's a fact that should reorganize how you think about depression: after decades of brain scans, autopsies examining serotonin receptors, even studies putting needles in people's spines to measure serotonin metabolites, researchers have found no consistent biological marker for depression or anxiety. None. That's why there is still no lab test and no brain scan in psychiatry. Not because we haven't looked. Because it isn't there.
Now compare that to what the research does show, consistently and powerfully: childhood trauma. Social isolation. Poor physical health. Lack of meaning and purpose. The correlation between problems in these areas and mental health struggles is strong and undeniable. Your grandmother could have told you this list. The data backs her completely.
So look at America through that lens. Seventy percent of us are overweight, thirty percent obese. We're more socially isolated than any generation in history. We soothe ourselves with inflammatory junk food and screens. And our response to the mental health crisis this produces is to call it a biological disease and prescribe accordingly, while the actual drivers, the ones with the strong evidence, go unaddressed as a matter of national policy.
Why do we keep looking in the wrong place? Because an entire industry depends on the answer being "it's medical, it's your brain, get on the drugs." There's no product to sell for loneliness. No pill margins in meaning and purpose.
Imagine what we could do as a country if we put even a fraction of our mental health spending into the things that actually correlate with mental health. That conversation is sitting right there, and almost nobody in power is having it.
If you're looking to safely taper off a psychiatric medication, comment TAPER and I'll send you my free tapering guide. It's the exact protocol we use with our patients at TaperClinic.
A new RCT shows that even when UPF meals are nutritionally matched to non-UPF meals, they trigger higher insulin spikes, alter energy metabolism, and also change how your brain responds to food cues. Food processing matters far beyond macronutrients! https://t.co/wQvoiO6bWi
We're urging Medicare to make nutrition and metabolic health a bigger part of preventive and chronic disease care—by expanding access to medical nutrition therapy, helping rural clinics offer nutrition & diabetes services & more. Read our @CMSGov comment:
https://t.co/GMXhoDaJ8F
@BiggestComeback Similar. Now I only get sick if I have super poor sleep for multiple nights like when I travel, take an abbreviated red eye flight etc.
🚨🚨🚨🚨🚨WHOA!!!🚨🚨🚨🚨🚨
Our film, tcc #TheCholesterolCode just got picked up by @PrimeVideo!!!
It's now part of their catalog and you can watch it free -- right now!
👇👇👇👇👇👇👇
https://t.co/WEbQkdr23d
@Boltsfan1725@TrimpeChristine Sometimes personal growth includes bringing new folks into our lives.
Sometimes our loved ones eventually come around. After 6-7 years my mom finally joined. At 86 she was delighted with the mental benefits from KMT.