The Metascience Observatory

Building a database of replications, pioneering AI-powered large-scale literature review, and building an AI agent to do forensic metascience at scale.

[The Metascience Observatory @MetascienceObs]

Earlier today we sent out our newsletter for Q1 2026!

Read about our #LongCOVID dashboard, the growth of our replications database, AI for forensic metascience, and the latest metascience news => https://t.co/C5x5xxiB5L

Subscribe for future emails => https://t.co/iyGKhW1mR9

[The Metascience Observatory @MetascienceObs]

@EricTopol journal seems to be down
https://t.co/2QEPaeCsAf

[The Metascience Observatory @MetascienceObs]

A new podcast we are listening to with great interest! Recent episodes with @mumumouse2, @BrianNosek, James Heathers, Tim Errington, and others

[Randy Ellis @randalljellis]

I started a podcast! Metascience Matters features conversations with metascientists.

Two episodes are live:

@chiragjp on Exposomics and Vibration of Effects: https://t.co/1yIffxm1bC

Florian Naudet on Clinical Trials, Registered Reports, and Psychiatry: https://t.co/4mW8J9AOLW

[The Metascience Observatory @MetascienceObs]

Our first newsletter just went out. Read it on Substack! https://t.co/VmBFjV1UtP #metascience

[The Metascience Observatory @MetascienceObs]

@conorsen men are less risk adverse, not surprising

[The Metascience Observatory @MetascienceObs]

@WorkAsIntended @MTupala @EricTopol The effectiveness against the original strain is 90% with the right dosing schedule ("half dose" first & then a long stretch between doses). According to observational data from Scotland, one dose of AZ is better than Pfizer at preventing hospitalizations https://t.co/vtmxBqSf94

[The Metascience Observatory @MetascienceObs]

@TonyBurnetti @EricTopol @KimberlyBlumen1 @TonyBurnetti Can you explain your reasoning? Vaccine hesitancy is dropping, see the Pew data on this :https://t.co/9rIkeJxAVZ : By approving earlier, those who are hesitant would have more time to become comfortable w vaccine, after observing friends & loved ones get it.

[The Metascience Observatory @MetascienceObs]

@EricTopol @KimberlyBlumen1 When will you take responsibility for your roll in the decision to not issue EUAs after Phase I/II? That caused tens of thousands of preventable deaths. It was clear from Phase I/II data & prior knowledge the safety risk from vaccines was very low, but risks from COVID very high!

[The Metascience Observatory @MetascienceObs]

@blockedthought_ Actually AZ has not yet been approved via EUA by the FDA!!

[The Metascience Observatory @MetascienceObs]

@LarryHogan : Liberate the AstraZeneca vaccine from the FDA! - Sign the Petition! https://t.co/iL1QthFG2x via @Change