Thrilled to share my first publication in ACIE: Modular Construction of Cyclic and Linear Quaternary Carbon Centers through Visible‑Light‑Induced Triplet Nitrene Transfer Reaction 🎉
Now online!
🔗 https://t.co/BKVwAPpZjJ…
#Photochemistry#OrganicChem#Nitrene
Check out the recent paper: “O-Vinylhydroxylamines for De Novo Pyrrole Synthesis”, co-authored by Charlotte Randolph, Oleksander Buravov, Zachary Grimm, Pavel Mykhailiuk, and László Kürti.
This study shows that O-vinylhydroxylamines enable the de novo construction of pyrroles through an aza-Michael/oxaza-Cope [3,3]-sigmatropic rearrangement/aromatization cascade with activated alkynes. The results establish O-vinylhydroxylamines as versatile building blocks for the synthesis of highly functionalized pyrroles, enabling substitution patterns that previously required harsher or more complex approaches.
Read more: https://t.co/7a6mrYDfs4
Expedient Synthesis of N-Protected/C-Activated Unnatural Amino Acids for Direct Peptide Synthesis | Journal of the American Chemical Society https://t.co/ma1gwxr7nF
Enantioselective Construction of 1,3-Stereogenic Centers via 1,3-Borylamination of Conjugated Dienes | Journal of the American Chemical Society https://t.co/l6Jukb3Ekr
Mechanistic evaluations of photocatalytic access to N-centered radicals and nitrenoids, which was directed by Prof. Sukbok Chang (director of IBS). https://t.co/49bdc7GPLV
A Comprehensive Mechanistic Scenario for Asymmetric Cross-Coupling Reaction of Diazoacetate and Terminal Alkyne under Copper Catalysis | Inorganic Chemistry https://t.co/H0gVVyrU2c Wang and co-workers @InorgChem#diazoacetate#alkyne#copper#M06_L#NCI#indane#bisoxazoline
Time-controlled divergent synthesis - With different reaction times, two distinct fluorinated strained rings can selectively be accessed from the same starting material by @HuanmingHuang and co-workers • https://t.co/u4OtVwPzaF
Iridium-Catalyzed Nitrene-Mediated Enantioselective 1,2-Hydride Shift Enabled by Attractive Noncovalent Interactions for Chiral δ-Lactam Synthesis | Journal of the American Chemical Society @TotalSyntheses https://t.co/1FOnNUvlXp