Brilliant talk by @EricVivier1@InnatePharma describing Innate's portfolio of biologics aimed at modulating of NK cell and CD8 T cell functions in TME. Very exciting to see unpublished data on bi-specific engagers as well as on adenosine pathway.
ICYMI, @sloan_kettering scientists have identified new structures that play a critical role in one of the most protective kinds of #intercellular communication – the “lethal” interaction between a cytotoxic #Tcell and its targets: https://t.co/bSxUshQQha
study provides mechanistic insight on the role of KRAS in colorectal cancer resistance to immune-checkpoint inh https://t.co/Q9ImztF918 #colorectalcancer
Long lines of questions for the NK cell talks at @KeystoneSymp Lewis Lanier, Alberto Mantovani & myself we’re inundated by Q’s on how to drug the NK cell response to cancer. Amazing time to be a cancer immunology researcher
In an analysis of KEYNOTE-028, T-cell–inflamed gene-expression profile, PD-L1 expression, and TMB were found to predict efficacy of pembrolizumab across 20 cancer types: https://t.co/YDgg5q9BYM #ImmunoOnc