MuscleX_Lab

The lab specializes in studying the structural properties of striated muscle using Small-Angle X-ray diffraction.

[MuscleX_Lab @MuscleX_Lab]

Illinois Tech-Led BioCAT Wins NIH Renewal to Continue Operating Fiber Diffraction Beamline at Argonne’s Advanced Photon Source | Illinois Institute of Technology https://t.co/zp53vQuuRZ

[MuscleX_Lab @MuscleX_Lab]

We are hiring a beamline scientist to run the fiber diffraction program at BioCAT. Please spread the word! https://t.co/T7qVxIUEM4

[MuscleX_Lab @MuscleX_Lab]

The Biophysics Collaborative Access Team Awarded $8M Grant. https://t.co/CAGOFyJ9sb

[Biophysical Journal @BiophysJ]

#OPENACCESS: A higher ATP concentration turns thick myosin filaments into an ON state, leading to altered cross-bridge kinetics. These X-ray data correlate low ATP levels to the inactivated myosin state observed in certain heart diseases. https://t.co/GV6oP8w3dr

[MuscleX_Lab @MuscleX_Lab]

Our symposium is just around the corner—don’t forget to register to receive the Zoom link for the event. We look forward to seeing you there. https://t.co/cjcmuyaCT6 https://t.co/baH0dABoPp

[MuscleX_Lab @MuscleX_Lab]

Excited to share BioCAT P30 grant received an outstanding overall impact score of 16! Grateful that the Fiber Core, which I lead, earned a perfect score of 10—a testament to the incredible work of our team and user community. We look forward to serve the field in the years ahead.

[MuscleX_Lab @MuscleX_Lab]

The “sound” of the heart beats!

[MuscleX_Lab @MuscleX_Lab]

The PI of BioCAT, Thomas Irving, will give a talk today at 3:15-4:30pm CST titled “30 years of Muscle Diffraction at BioCAT - What have we learned about muscle contraction?”
Welcome to join
https://t.co/iGtVT2fvym

[MuscleX_Lab @MuscleX_Lab]

It was very nice to welcome our muscle users @HesselAnthony @mikuehn8 @vivekpjani back after two years for @advancedphoton upgrade. BioCAT remains the state-of-art facility for muscle X-ray diffraction.
Proposal for next run due in two days!

[MuscleX_Lab @MuscleX_Lab]

@jonathankirk @LoyolaChicago Henry is the poster boy 👍

[MuscleX_Lab @MuscleX_Lab]

A definition of a long haul. Very glad to see this one came through after years of work.

[Anthony Hessel, PhD @HesselAnthony]

🚨📢Paper alert! Real progress on identifying why residual force enhancement occurs! This was a study I dreamed about since grad school. Please share!

The distinctive mechanical and structural signatures of residual force enhancement in myofibers | PNAS https://t.co/TKf7HH99gP

[MuscleX_Lab @MuscleX_Lab]

Very productive run at @CHESS_user with @vivekpjani and Marcus. We collect patterns from human heart tissue (HFpEF, HFrEF, HCM, SVD) probably for the first time ever there, and more patterns from animal hearts. Looking forward to come back soon!!!

[MuscleX_Lab @MuscleX_Lab]

Very nice to see this project in the press!

[Luca Fusi @LucaFusi2]

Celebrating #PhysiologyWeek with:
Load-dependent activation of the myosin filament in the heart
https://t.co/YXSpNP7UGY
https://t.co/EOJMYHSYrd
@KclPhysiology @esrfsynchrotron @brunello_lab @JPhysiol

[MuscleX_Lab @MuscleX_Lab]

Congrats @vivekpjani well deserved

[MuscleX_Lab @MuscleX_Lab]

@OchDr Really hope it won’t, but it is probably a wishful thinking

[MuscleX_Lab @MuscleX_Lab]

First decoration at the new Fulton Lab

[Journal of Physiology @JPhysiol]

🎉The journal cover of our June 2024 issue nicely displayed by Dr Weikang Ma at the BioCAT, @argonne @illinoistech🎉

The cover image comes from X-ray diffraction patterns in Zhao et al.'s work examining differences in thick filament activation! 🔗https://t.co/91oQXtH2I5

[MuscleX_Lab @MuscleX_Lab]

We are glad to share that we got all the beam we expected from the new @advancedphoton into our experimental hutch, ~4 × 10^13 photons/sec at 250um ×250 um unfocused. We expect to welcome users back in the near future after the scientific commissioning.

[MuscleX_Lab @MuscleX_Lab]

@OchDr Yes

[MuscleX_Lab @MuscleX_Lab]

@OchDr When they say we are really sorry for the delayed response, they don’t really mean it.

[MuscleX_Lab @MuscleX_Lab]

@PKH_Lab Qingdao is very close to my hometown, enjoy