Natalie Trigg

Examining the function of sperm small RNAs at @ChildrensPhila and @Penn 🇦🇺 in 🇺🇸
Avid list-maker, lover of the sky and all things science ☀️⚽️🔬

[Natalie Trigg @NATrigg]

Excited to have this published! We identify a subset of microRNAs acquired by sperm from the epididymal epithelium that regulate gene expression in preimplantation embryos > https://t.co/7TcbDK1GCs
Huge thanks to @ColinConine for the support and guidance during this project

[Natalie Trigg @NATrigg]

If you're interested read it in @ReprodJournal ! Big thanks to the team, @ColinConine @TakuKambayashi Simon, Jordan, Maddie, Molly & Mike

[Natalie Trigg @NATrigg]

The 'swollen' phenotype was from epididymal tubule breakdown and cell infiltration and was accompanied by many gene changes. Interestingly, while offspring of germ-free dads didn't show the severe swollen epididymis, they shared many epididymal gene changes.

[Natalie Trigg @NATrigg]

Working with germ-free mice with the @TakuKambayashi Lab we saw a 'swollen' epididymal phenotype occurring, so we took a closer look https://t.co/IQ3X6hsLZT

[Natalie Trigg @NATrigg]

A lack of commensal microbiota influences the male reproductive tract intergenerationally in mice https://t.co/IQ3X6hsLZT

[Natalie Trigg @NATrigg]

@DrAnyaArthurs @RobsInstitute Congrats Anya!

[Tessa Lord @TessaLord1]

Pleased to share my latest review article published with @SpringerNature in @NatRevUrol: Exploring the pathophysiological effects of hypoxia on testis function and spermatogenesis https://t.co/AGyg3QC3WV

[Natalie Trigg @NATrigg]

This one was a big group effort! Not possible without @JESchjenken, @BrettNixon13 and the rest of the team

[Natalie Trigg @NATrigg]

🔥🔥 A modest increase in temp doesn't affect sperm functionality but does alter sperm small RNAs, embryo dev and gene expression in mice plus more. https://t.co/HgNdEqk8th

[Jamie Hackett @hackettlab]

📢Postdoc available! We are looking for curious minds to answer big questions using epigenome editing

Join us at @EMBLRome - we offer training, supportive environment, top salary and scientific excellence. Also - sun, culture & Italian food😉

Info+apply:
https://t.co/1LzuHBds20

[John Schjenken @JESchjenken]

@CTamessar from @UON_research @HMRIAustralia paper on the influence of seminal fluid extracellular vesicles (SFEV) on sperm function now published. Here we show that SFEVs deliver cargo to sperm to elicit subtle changes to their function@Repro_Fertility
https://t.co/T2FnrkT5Rp

[Natalie Trigg @NATrigg]

Interested in studying the impact of environmental stressors on sperm epigenetics? A PhD position is open to domestic candidates to work in @BrettNixon lab. See link for more details or get in contact! @UON_research @HMRIAustralia https://t.co/0lhlK7lM1I via @uni_newcastle

[Natalie Trigg @NATrigg]

@TheBaleLab @neuronickole @EricTopol Interesting! I'll be keenly following along.

[Natalie Trigg @NATrigg]

@GoldingLab @ColinConine Thanks Mike!

[Natalie Trigg @NATrigg]

@neuronickole @TheBaleLab @EricTopol Thanks! Of course, I'm curious if/when/how these cells recover. Great work.

[Natalie Trigg @NATrigg]

@HAIYANGWANG6 @NatureAging @SpringerNature Incredibly cool study!

[Natalie Trigg @NATrigg]

@Tod_Fullston Thanks Tod!

[Colin Conine @ColinConine]

The first publication exclusively from my lab! Led by the amazing @NATrigg (who I will let tweet more details)

[Cell Reports @CellReports]

Epididymal acquired sperm microRNAs modify post-fertilization embryonic gene expression https://t.co/6IlM5NreUL