Nuria Lopez-Bigas

I DON'T USE TWITTER
Follow me at:
at @irbbarcelona. Computational cancer genomics. Leading the @bbglab

[Nuria Lopez-Bigas @nlbigas]

Children who develop two independent tumors during childhood are extremely rare. We wanted to shed light into those exceptional cases using genome analysis

We also reveal the mutational footprint of chemotherapy in normal tissues using duplex sequencing of autopsy samples

👇

[Mònica Sánchez Guixé @guixe_m]

Our work on the origins of second malignancies in children is out in Cancer Discovery @IRBBarcelona @bbglab @IRSJD_info
https://t.co/OICCeoTFOC
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[Nuria Lopez-Bigas @nlbigas]

Molt trista per aquesta notícia. Gran professor, comunicador i científic. Una persona propera que ha deixat empremta a tots els que hem tingut la sort d'interaccionar amb ell. Deixa un llegat immens a l'IRB i a la ciència al nostre país.

[IRB Barcelona @IRBBarcelona]

Amb profunda tristesa, lamentem comunicar la mort aquesta passada matinada del Dr. Joan Guinovart, fundador, exdirector, exinvestigador i professor emèrit de l’IRB Barcelona.

El Dr. Guinovart ha estat una figura clau en l’àmbit de la bioquímica, deixant una empremta inesborrable tant a nivell científic com de gestió. La seva intel.ligència, lideratge i el seu profund humanisme han estat fonamentals per a les persones que hem tingut la sort de compartir camí amb aquest home irrepetible i per al món de la recerca.

Expressem el nostre més sentit condol a la seva família, amics, companys i a tota la comunitat de l'IRB Barcelona.

Joan, la teva absència ens deixa un gran buit, però el teu llegat perdurarà per sempre.

Et recordarem sempre, capità.

[Tim Coorens @TimCoorens]

Spread the word! Registration for the "Mutations in Time and Space" conference is open. The meeting is all about the origins, patterns, and consequences of mutations across cells, individuals, populations, species. Abstract submission deadline: Jan 17th https://t.co/KMEHdXnLMQ...

[UCSF Helen Diller Family Comprehensive Cancer Ctr @UCSFCancer]

This Friday 12/6 at 4pm, Núria López-Bigas, PhD @nlbigas @IRBBarcelona @nlbigas.bsky.social presents "Somatic mutations in tumors and normal tissues" at our Friday Seminar Series in Basic and Translational Research https://t.co/u78QSw2qNt

[Nuria Lopez-Bigas @nlbigas]

Once upon a time, Twitter was great for scientists
Lately, it burned me out, and I gradually drifted away

I'm very happy to see that many scientists I admire and whose work I enjoy following are now on Bluesky

This is my bsky profile 👇
https://t.co/nfoNndCwsg
See you there!

[Kamila Naxerova @naxerova]

To all the local folks (@harvardmed, @MGH_RI, @DanaFarber, @BrighamWomens):

We are very excited that @nlbigas is giving a seminar in our department tomorrow - please come join us!

[Nuria Lopez-Bigas @nlbigas]

@LupinCambridge @NatureGenet @AlbertHerms @sangerinstitute @MariaPAlcolea Congratulations!! This is a great work.
Good to see it published 👏🏻👏🏻

[Nuria Lopez-Bigas @nlbigas]

ASEICA rocks!!
Amazing opportunity to hear Katalin Kariko story
(Only for ASEICA members)

[ASEICA @ASEICAnews]

➡️No te pierdas el próximo MEET THE EXPERT con la premio @NobelPrize Katalin Kariko (@kkariko) (@Penn)

"My winding road towards mRNA therapy"

⏰10/10/24 (13:00h)
Acceso libre socios ASEICA (previa inscripción)

✍️https://t.co/X9174ofnCQ

#ASEICA4You

[bbglab @bbglab]

We are very happy to announce that a dual new release of intOGen (https://t.co/cMjVul9N1I) and boostDM (https://t.co/wTJjD8ymDl) is out today! 🎉 Here is a thread summarizing the main updates:👇

[Nuria Lopez-Bigas @nlbigas]

@S_J_Aitken @YaleCancer @yalepathology @aitken_lab @clarnedo @_HAN1999 @MRC_TU @Cambridge_SBS @Cambridge_Uni @YaleMed @MuschenLab @DrEricWiner @YaleGenetics Best wishes Sarah and Aitken_lab for this new adventure. They are lucky to have you.

[RACiencias @RACiencias]

‼️ Abierto el plazo para presentación de candidaturas a los premios al Jóven Talento Científico Femenino
🚧 Hasta el 20 de octubre
⚙️ Premios organizados por la Fundación de la #Raciencias y @MastercardES
➕ https://t.co/T6XQ9raoaH

[Dr. Patrick Hwu @PatrickHwuMD]

#ScienceSaturday

Immune checkpoint blockade has revolutionized #cancer therapy, but this works much better for some patients compared to others. What are the major factors distinguishing response? In a recent report, investigators evaluated the clinical, genetic and transcriptomic data for 479 metastatic cancer patients treated with #immunotherapy and identified 5 major factors for response: “tumor mutation burden, T cell effective infiltration, transforming growth factor-beta activity in the microenvironment, prior treatment and tumor proliferative potential”. This was validated in 1491 patients in 6 individual cohorts. @nlbigas

➡️ Studies like this will help us personalize immunotherapy decisions and design future combination treatments.

🔗 Here’s a link to the full study: https://t.co/KaTiLOk3ZK

[Nuria Lopez-Bigas @nlbigas]

Check also the Views paper on our work written by Christopher Arends and Siddhartha Jaiswal

Thanks for the accurate summary and perspective on our work @jaiswalmdphd

https://t.co/PwxkYfiWVg

[Nuria Lopez-Bigas @nlbigas]

Our latest paper -> On identifying the mutations driving clonal hematopoiesis using machine learning models - BoostDM-CH

Great team work by @SantiDemajo, @JoanEenric, @fmuinos et al

Tweetorial 👇

[Nuria Lopez-Bigas @nlbigas]

Our latest paper -> On identifying the mutations driving clonal hematopoiesis using machine learning models - BoostDM-CH

Great team work by @SantiDemajo, @JoanEenric, @fmuinos et al

Tweetorial 👇

[Santi Demajo Meseguer @SantiDemajo]

‼️ The final version of our article “Identification of Clonal Hematopoiesis Driver Mutations through In Silico Saturation Mutagenesis” is out in Cancer Discovery @CD_AACR: https://t.co/ug0meqg10b

Learn more about our findings in this thread 👇🏽

[Centre for Genomic Regulation (CRG) @CRGenomica]

🔵We are seeking a new director!

The Centre for Genomic Regulation (CRG) is an independent research institute located on the shores of the sunny beaches of Barcelona. It is part of the public @iCERCA research system of Catalonia.

We have one clear mission: to understand the complexity of life. We do this to advance knowledge for the health and wellbeing of people, as well as to advance economic prosperity.

🔗Job offer: https://t.co/LOJMtRSeoS
🔗Full Brochure: https://t.co/aqPAAzoc05

[IRB Barcelona @IRBBarcelona]

For today’s International LGTBIQA+ #Pride Day, we want to give a special shout-out to our (and all) #LGTBIQA+ members! We are proud of you and how you enrich the scientific world. Also, we are grateful to our welcoming #IRBBarcelona community who makes Diversity and Equality our pillars. Thank you!
#Pride2024

[Nuria Lopez-Bigas @nlbigas]

@marta_mele_m @mele_lab @BSC_CNS @Bioinfo4women Congratulations!! 👏🏻 Well deserved! @BSC_CNS ara lucky to have you.

[Nuria Lopez-Bigas @nlbigas]

Springer Nature made over $500M in profit in 2022, 27% margin 💰 (outrageous given most publishing costs are covered by public funds)

Nature's editors on strike for fair pay

Editors are highly skilled professionals who deserve full respect

I signed👇
https://t.co/PzCFj3O8S0

[IRB Barcelona @IRBBarcelona]

💥Thank you to all the brilliant participants & attendees of our recent #BarcelonaBioMed Conference! 🙏 Your passion & dedication to advancing science through #cancer promotion & prevention is truly inspiring!✨

👉Special thanks to @FundacionBBVA for making it possible.

🗣️💡The exchange of knowledge & ideas last week in #Barcelona was invaluable in pushing the boundaries of this promising field😍

Thank you all!🙏

Watch the conference video here:

▶️ https://t.co/DeinJQe6GT

#CancerResearch

[EACR @EACRnews]

We’re delighted to announce that @samuels_yardena (@weizmannscience) has been elected as EACR President!

@Johanna_A_Joyce (@unil @OncoUNILCHUV @Ludwig_Cancer) becomes President-Elect, and Rene Bernards becomes Past President 👏👏👏

#EACR2024

[Nuria Lopez-Bigas @nlbigas]

Very interesting insights into DNA damage and repair from the analysis of #LesionSegregation and #multiallelism.

Congrats @mst_paralogue @S_J_Aitken @craigandersn @odom_lab and all.

Don’t miss the paper and tweetorial👇🏼

[Sarah Aitken @S_J_Aitken]

🎉New paper🎉Introducing #StrandInteractions, the sequel to #LesionSegregation, published today @Nature

Strand-resolved mutagenicity of DNA damage and repair https://t.co/VTP3h139Q4

Here’s what we discovered about (a)symmetry in replication, transcription & #mutagenicNER
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