A new study shows that a small cluster of neurons called the locus coeruleus has a specialized pathway to the brainstem that controls sound-evoked awakening with the release of norepinephrine. @LabNir@NMatosevich https://t.co/b1s6gzKVSr
My PhD paper is finally out! 🎉 We show how specific LC pathways shape sound-evoked awakening, revealing LC heterogeneity in action.
So grateful to all the amazing people who made this possible 🙌
🚨 New paper alert! 🚨(1/6)
Excited to share our work, out now in Science Advances
We show that a rapid norepinephrine surge along a brainstem pathway (LC→PRN) is a key driver of sound-evoked awakenings
https://t.co/O9q4qWOmzR
Tired of spending months teaching every new student how to clean and analyze sleep EEG? 🧠💤
We were too. @LabNir
That's why we built SleepEEGpy- a simple open-source pipeline to make sleep EEG research faster, easier, and standardized! 👇
https://t.co/72TQerpisB
Deficient synaptic neurotransmission results in a persistent sleep-like cortical activity across vigilance states in mice: Current Biology https://t.co/4Ss5Zyk8ff
Here's our latest issue: https://t.co/ImgPc6z4Dp
The cover is for a Perspective piece by Lüthi & Nedergaard who discuss microarousals, and propose an inverted U-shaped relationship to reconcile their essential and disruptive roles: https://t.co/K7cxWIoYAg
Cover by Nadia Alzoubi
In conclusion, we found LC heterogeneity in the context of sleep and arousal. More specifically, our work reveals a specific pathway critical to sound evoked awakenings.
Excited to share our new preprint out on biorxiv! We found a specific LC pathway that influences sensory evoked awakenings from NREM sleep. @LabNir https://t.co/6wLOF2WVEb
Finally, selective synaptic silencing using an optoGPCR PdCO demonstrated that silencing LC synapses in the PRN is sufficient in elevating sigma power in EEG during NREM sleep.
Out today in @CellCellPress !
We show that oscillations in norepinephrine and cerebral blood volume are the missing pieces that link NREM sleep to clearance of waste from the brain 🧠💤 https://t.co/cvfmkxNzJt
Let’s share some data! @LabNir 🧵
We’re thrilled to announce our new paper in @ScientificData featuring an open iEEG dataset from two medical centers and an ML model for detecting interictal epileptiform discharges during sleep 🧠⚡
👉 https://t.co/wgmfvLRxaj
I'm usually not into writing reviews, but this was a request was to imagine the future of transcranial ultrasound neuromodulation. Needless to say, I had some inspiration
https://t.co/oXTaTE2Hd7
📢My PhD work on the "Deleterious effects of social isolation on neuroendocrine-immune status and cancer progression in rats" is finally out in
@BrainBehavImm!
🔗https://t.co/ZAIcpTsSIA
@of_sagol
@PNIRS
Check out the latest from our lab, an in-depth look at the neural and peripheral response to social isolation in rats. Led by the exceptional @estherina_t who is a force of nature! 💫