Noha Said Helal

Pathologist, MD, with an interest in GIT path #GIpath #liverpath, uropathology #GUpath #prostatepath and nephropathology #nephropath #renalpath

[Lorand Kis @kis_lorand]

We are happy when we see this type of breast cancer 👌💪🔨
#breastpath #pathology

[Dr Kamlesh Darji @DrKamleshDarji1]

Algorithmic approach to the Renal Biopsy #PathX

[Samson W. Fine, MD @rovingatuscap]

'Feelin' Groovy' - florid urothelial metaplasia in a prostate needle biopsy, mimicking basal cell hyperplasia and HGPIN at low magnification; at high magnification cytoplasmic vacuoles (upper R) & nuclear grooves (lower R) in the metaplastic cells aid in identification #gupath

[Ting Zhao, MD @TingZhaoPathdoc]

Urothelial carcinoma in-situ (UCIS) involving von Brunn’s nests #GUpath
▶️Major morphological patterns (PMID: 11224606; figures below):
💠Large cell (pleomorphic or non-pleomorphic): abundant cytoplasm
💠Small cell: scant cytoplasm
💠Clinging: denuded urothelium with patchy, usually single-layered of atypical cells
💠Cancerization: pagetoid spread; undermining
💠Plasmacytoid (PMID: 31368912) @slusagar
▶️This UCIS shows a large-cell pleomorphic pattern with pagetoid spread
▶️Morphological patterns do not imply different prognosis (PMID: 23397277)
▶️Subclassification of UCIS morphologic patterns is not required in routine reports

[Liang Cheng, MD @LiangChengMD]

Redefining the Landscape of Genitourinary Cancer Precursors: The International Society of Urological Pathology Consensus Recommendations

I am pleased to share that our Platinum Opinion article in European Urology @EUplatinum （journal impact factor 25) is now available online and indexed in PubMed (PMID: 41934039).
This work represents the outcome of the ISUP Florence Multidisciplinary Consensus Conference, which established a contemporary framework for the definition and reporting of genitourinary cancer precursor lesions. By clarifying areas of consensus and highlighting key knowledge gaps, these recommendations provide practical guidance for the diagnosis and management of premalignant lesions in genitourinary cancers.
Free full-text access:
https://t.co/SwL0tykatm
https://t.co/V1rLxvZKyp

[Miruna Popescu, MD @MirunaPopescu13]

EBB from a middle-aged F with a dual clinical history. One of them is breast cancer some years ago.

What does #pathtwitter think?🔬
#lungpath #thoracicpath

[Charlie Herndon @DrCycloPath]

#PathQuiz 🔬 #Stomach

A) Foveolar-type adenoma
B) Fundic gland polyp
C) Pyloric gland adenoma
D) Oxyntic gland adenoma
#Pathology #GIPath @IARCWHO
Clue in caption 🧐

[Charlie Herndon @DrCycloPath]

#PathQuiz 🔬
A) Fundic gland polyp
B) Gastric hyperplastic polyp
C) Gastric adenoma
D) Pyloric gland adenoma

#Pathology #GIPath

[Ziad El-Zaatari @ziad_zaatari]

🔬📸 "Polka Dots and Bubbles" 🔵🫧⚪️ ~ Glycogenated cells in a Low Grade Papillary Urothelial Carcinoma ~ #GUpath #Pathology #PathArt

[Dr. Arkadip MD @pathognosis22]

Tried to summerise #sinonasal #SRBCT #pathognosis #pathnotes

[Dr. Arkadip MD @pathognosis22]

Daily #breast #pathology reporting companion for #beginners #pathognosis

[Gladell Paner, MD @GladellPaner]

#Prostate needle core biopsy.
Diagnosis???
🔬Intraductal carcinoma (IDC-P)
🔬Atypical intraductal prolif (AIP)
🔬Cribriform invasive carcinoma

Answer in comment.
#GrayZonePath 40 #GUPath

[Abhijit Das, MD @AbhijitSurgPath]

Happy New Year 2026

[Mark Ong @DrMarkOng]

I'm working on a teaching presentation on Hodgkin's lymphoma.

Picture below contains HRS-like cells from 9 different cases.

Which ones are classical Hodgkin's lymphoma and which ones are something else?

#hemepath #pathtwitter #pathology

[Liang Cheng, MD @LiangChengMD]

Must-read! The latest issue of the American Journal of Surgical Pathology features several practice-changing guideline and consensus papers that will serve as essential references for pathologists, urologists, oncologists, and medical professionals interested in urologic malignancies. Big congratulations and sincere thanks to our outstanding expert consensus panelists for their phenomenal scholarship, leadership, and collaborative efforts in advancing the practice of urologic surgical pathology! More to Come with Working Group 3- 5  Recommendations  - Stay Tuned @IntSocUropath
-    Iczkowski KA et al. International Society of Urological Pathology Consensus on Cancer Precursor Lesions. Working Group 1: The Prostate. Am J Surg Pathol 2025;49:e33-45. PMID: 40545966  https://t.co/QrTvaJ2rxf
-    Downes MR et al. International Society of Urological Pathology Consensus Meeting 2024: Working Group 2 Preneoplastic and Precursor Lesions of the Urinary Bladder. Am J Surg Pathol2025;49:e46-57. PMID: 40590266
https://t.co/N2idLVrtYB
-    Shah RB et al. Genitourinary Pathology Society and International Society of Urological Pathology White Paper on Defining Indolent Prostate Cancer. Am J Surg Pathol 2025; 49:e27-32. PMID: 40444986.   https://t.co/NvQy3FdH5P
-    Reis H et al. The Dublin International Society of Urological Pathology (ISUP) Consensus Conference on Best Practice Recommendations on the Pathology of Urachal Neoplasms. Am J Surg Pathol 2025; 49:e18-26. PMID: 40471793 https://t.co/2fWjqaZVuK

Interested in urologic pathology/GU malignancies? Please join the International Society of Urological Pathology (ISUP) and connect with a global community of GU experts:
👉 https://t.co/PmTWyjwq6e

@JLHornick @AJSPjournal

[Zemplén Pataki, MD, PhD @ZemplenPataki]

Pelvis. What is your diagnosis? 🔎
Poll below 👇

#PathPuzzle 🕵️‍♂️
@UMichPath #Pathology #PathX #PathTwitter

[Denis Wirtz @deniswirtz]

Still my favorite 3D reconstruction of a pancreatic tissue.

Using the CODA workflow, we mapped a billion individual cells in 3D.

Red: pre-cancer lesions
Navy blue: ducts
Light blue: islets of Langerhans
Purple: acini
Green: blood vessels

More here: https://t.co/RsB0RYoPIy

[C. Christofer Juhlin @DrJuhlin]

Spindle cell neuroendocrine tumor (NET) of the duodenum - an ultra-rare entity often mistaken for sarcoma, GIST, solitary fibrous tumor, or even paraganglioma. Accurate diagnosis requires careful histopathology and immunoprofiling! Some IHC images in the thread below...

[Nicole Zalles MD, PhD @ZallesNicole]

A stunning example of a clear cell renal cell carcinoma going bad- classic morphology on the left, transitioning into rhabdoid features on the right. A great section! #pathology #GUpath #PathTwitter

[Abhijit Das, MD @AbhijitSurgPath]

Prostate cancer: Gleason grading
(Basic facts for residents)