Thrilled to be part of this amazing collaboration exploring the conformational space and structural dynamics of heterogeneous RNAs - @TzaiYun@Degenhardt_MFS@YunXingWangLab@jinweizhang. Excited to see our work published in @Nature just in time for the holidays!
How to repurpose a #tRNA enzyme into a global stress sensor? Co-led by @CharlesBNader, Swati Gaikwad, Soheila Bahmanjah, w/ Alan Hinnebusch lab, in
@PNASNews, we describe how stress kinase Gcn2 adopts and molds Histidyl-tRNA synthetase as a regulatory hub. https://t.co/1IjEEPuGJ6
How many different things can you grab using a small β-barrel? Sugars, #DNA,#RNA,#tRNA? All of the above. Led by Aline Umuhire Juru, Rodolfo Ghirlando @NatureComms, we find a class of OB-folds in Trbp and Arc1p recognize tRNAs by their universal 3’ ends. https://t.co/dJCbd7Z7Mo
Excited to share our latest story revealing an RNA-centric mechanism where menRNA drives its own conformational isomerization and fate. @jinweizhang@NatureSMB Check it out 👇
https://t.co/iMYz0knL0K
How does one #tRNA-mimicking mascRNA from #MALAT1 get one CCA tail and is stable, while menRNA from #NEAT1 receives two marking it for decay? We uncover a #riboswitch-like mechanism where menRNA self-destructs by getting seconds.@IliasSkeparnias@NatureSMB https://t.co/qAEvXkvYq1
Happy to share our new study defining the structural and molecular mechanisms of #MALAT1 RNA maturation. Many thanks to all the co-authors who contributed to this work! Check it out in @NatureSMB 👇
https://t.co/hqr0YqKMIQ
📢An elegant dance between replication and histone retention for epigenetic inheritance!🥳Our new work shows that heterochromatin domains are specialized replication zones that preserve parental modified histones to ensure self-templated chromatin assembly https://t.co/JWXeySNvBC
Excited about our first #RNAsalon! On Dec 20th🎄we are hosting Marina Vidaki (https://t.co/J61VKNu0m8) and Costas Stathopoulos (@costas_stath) at 12:00 CET. Zoom https://t.co/qy0oJS6iyO @IMBB_FORTH Supported by the @RNASociety and @lexogen