👋🏽A reminder to all our authors and readers that you can now find us and connect with us on Bluesky: @natcellbio.nature.com
#Science#CellBiology#ScienceCommunication
🍰Interested in reading more about the study? Here is the N&Vs article written by Zainab Hussain & Mara H. Sherman.
👉🏽https://t.co/SB0uTlNYXT
https://t.co/ABCAmM9Cx4
☕️@ScientistJoanna, @RuggeroDavide & co perform a genome-wide CRISPRi screen and identify RBM42 as a ribosome-associated protein that modulates MYC translation and an #oncogenic mRNA program required for #PancreaticCancer growth.
👉🏼https://t.co/SWt5DxRqpF
https://t.co/IHcOfFPdDn
🍰Interested in reading more about the study? Here is the N&Vs article written by Kanda M. Borgognoni & Robin E. Stanley.
👉🏻https://t.co/hutOWbl3eU
https://t.co/8jkFi1tluQ
☕️Oborská-Oplová et al. report a conserved #mitochondria avoidance segment in the cytosolic ribosomal protein uS5 that prevents mistargeting of uS5 to the mitochondrial matrix and ensures cytosolic #ribosomal assembly.
👉https://t.co/5fDbdXAGUR
https://t.co/jmRpCvFEzv
☕️Wang et al. profile the #translatome of #hematopoietic#StemCells (HSCs) and downstream progenitors and lineages. They identify the SNORD113–114 cluster as a modulator of translation and self-renewal in HSCs.
👉🏿https://t.co/19cr3TcFW9
https://t.co/w7tj4jj2gJ
🍰Interested in reading more about the study? Here is the N&Vs article written by Nicoletta I. Petridou.
👉🏾https://t.co/4AQwPwJdo5
https://t.co/j5eNGL7eBu
☕️Afonso et al. show that, during #anaphase, chromosome movement can be driven by large cytoplasmic flows. These dynein-dependent cytoplasmic flows scale with cell size, slowing in smaller cells, thereby scaling anaphase.
https://t.co/IXOpxXJOKv
☕️Interested in how cells respond to #mitochondria#ProteinImport stress? Read our Review article by Nikolaus Pfanner, Fabian den Brave & Thomas Becker.
👉🏽https://t.co/jmcmuEo1On
https://t.co/Ozofg7zv81
☕️@szmyd_radoslaw @TheCesareLab@RadOncDoc_Gee & co: #DNArepair pathways impact if cells with DNA lesions arrest in mitosis. Homologous recombination-driven double Holliday junction formation elicits mitotic #CellDeath & suppresses inflammatory signaling.
https://t.co/UQVEQyOsl0
☕️@JingtaoGuo, @LeqianYu & co characterize an intact Carnegie stage 7 #HumanEmbryo at single-cell resolution in a spatially resolved manner.
👉🏻https://t.co/jwnVgl1w1n
https://t.co/j5UnsgvY1B
☕️Fulcher et al. show that #MDM2 times mitosis through self-catalysed ubiquitination and proteasomal destruction, triggering G1 arrest following delays in #mitosis associated with chromosome instability and #aneuploidy.
https://t.co/jJuXnFlwvG
☕️Ma et al. show that heterogeneous nuclear ribonucleoprotein U promotes the primed state in human #pluripotent stem cells by interacting with #NuclearMatrix protein, Matrin-3, and regulating primed-specific genes.
👉https://t.co/oDMxGRbi97
https://t.co/45lcpMkP85
💫NEW: @Brumbaugh_JB, Dempsey & co show that #H3K36 methylation maintains #intestinal epithelial fate commitment, whereas its suppression induces a plastic state and expression of genes involved in #regeneration.
👉🏿https://t.co/y6MnBmKXYO
https://t.co/xwuCoNw26k
💫NEW: @Sloan_Lab, @CaitlinSojka & co analyse the transcriptomic & epigenomic landscape of human #astrocyte maturation and identify an epigenetically regulated intermediate state linked with aberrant development in #glioblastoma.
👉🏾https://t.co/KNDGglEUhY
https://t.co/g8iRv5j0FZ
🍰Interested in reading more about the study? Here's the N&Vs article written by Joana C. Macedo, Maria M. da Silva & Elsa Logarinho.
👉🏻https://t.co/ZYAZ71Wvj8
https://t.co/iDOn8RMWlq
💫NEW: Hervé, Scelfo et al. show that #chromosome missegregation induces #mTORC2 - & ATR-mediated p53 activation via a mechanosensitive checkpoint at the nuclear envelope triggered by altered heterochromatin content and increased nuclear membrane tension.
https://t.co/OVSsYvyfLO