Structure of the human K2P13.1(THIK-1) channel reveals a novel hydrophilic pore restriction and lipid cofactor site https://t.co/uOT46CHjBS
New work from our lab shows a hydrophilic gate (the flow restrictor) and polyunsaturated fatty acid site. See also work from @ProfKalium
Very happy to share our work with the awesome (social media-less🤣) Henry Colecraft on using nanobodies to control calcium channel function. Special props 🥳🥳 to @NehaNirwan23 for showing us the atomic details of how these powerful reagents work.
https://t.co/eSqy4SuPOC
Structure of gabapentin bound to CaV1.2.
Important drug for pain, post-shingles neuralgia, and restless leg syndrome. Terrific work by the super team of Zhou Chen and Abhisek Mondal in the lab! 🥳
Structural basis for CaVα2δ:gabapentin binding https://t.co/zcLINryt2M
It's been wonderful seeing faculty come out to support academic workers, even though the administration has been sending intimidating messages to discourage faculty participation.
"UC works because we do!" Let's all fight for a #FairUCnow#UAWonStrike#UCstrike