7/7
4️⃣ New RCT showing Orticumab (anti ox-LDL) in psoriasis reduces FAI score in those with high baseline inflammation
@NehalMehtaMD
🔗 https://t.co/n6PjgXcZfC
😀The NIH MRSP program brings such wonderful talent to campus! Kudos to Christin for her dedication to understand what factors modify this incredibly dangerous type of coronary plaque present in patients BEFORE they ever have clinical heart disease. 🔥 @ToddVillinesMD@ElucidBio
Lipid-rich necrotic core (LRNC) is a rupture-prone plaque feature linked with MI. We leveraged machine learning to identify top predictors of LRNC modulation over 1 year in psoriasis. Thank you @NehalMehtaMD @TheBethesdaLabs and amazing co-authors! https://t.co/CGC9kQaO3f
FAT MATTERS. And here, CCTA-derived epicardial adipose tissue measurement make a difference on clinical outcomes.👇🏽 EAT is similar to visceral adipose tissue (VAT) which we have shown to drive coronary artery disease NCB in chronic inflammation🔥 https://t.co/ejD6yrRLJG
Can a fully automated measurement of EAT volume incorporated into routine interpretation of CCTA improve the risk stratification of patients across several important clinical outcomes? Read more to find out https://t.co/5RoYwmEL7O
@Charis_Oxford @imagingmedsci @NehalMehtaMD
BMI has always been a metric to assess for cardiometabolic risk. Waist:hip ratio performs well and better in chronic inflammation. We have shown the value of CT-measures of visceral vs subcutaneous adipose tissue prior, but now, check out how specific depots of fat matter 👇🏽
➡️Very honored to receive public, competitive, independent funding as principal investigator for our project in Psoriasis from @SaludISCIII
➡️Thanks to the whole team involved @MaruGBarderas@NehalMehtaMD@DrJoelGelfand
➡️Most importantly, thanks to all patiens involved
@foundmyfitness It’s also dangerous for incident development of cardiometabolic and cardiovascular diseases. Visceral adipose tissue is dangerous fat, coordinates a lot of atherogenic processes and expands in part through inflammation:
https://t.co/OzJ1LQzM4G
As we celebrate International Day of the Girl, I would be grateful if you would help me support Girls on the Run @GOTRI . #whoruntheworld
Check out my fundraising page - https://t.co/UbTxfNaIbA
.@pnatarajanmd, of @MGHHeartHealth, received the Anne Klibanski Award for Excellence in Mentoring. Named after Anne Klibanski, President & CEO of @MassGenBrigham, who has mentored hundreds of faculty members. This award is presented to an exceptional @MGHMedicine research mentor.
🔥@DrJoelGelfand and I planned four Vascular Inflammation in Psoriasis (VIP) trials to test the impact of treating psoriasis in cardiometabolic diseases. Our final one, VIP-A, was just published in @JAMADerm testing apremilast! #VAT matters https://t.co/soEXwu5k9B
🔥👇🏼Congratulations to @monikagoyal123 and the @adaptlab_cnh on earning another @NIH award to continue highly informative studies on how we can improve #healthequity outcomes in medicine. Bravo!👏🏼
Doppelgängers (individuals with nearly identical faces but unrelated) also have similar genetics but clearly distinct epigenomes and microbiomes https://t.co/e5nhCIS6mf @CellReports (coverage https://t.co/TopTtE9kDo @nytimes)