GIVEAWAY! ๐คฉ๐
Upgrade your lab style with a pair of @STEMCELLTech science socks.๐งฆ
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๐ฃ You have until June 30: https://t.co/V7rRAkYJTk
A @braincancercan-funded study led by Dr Ian Lorimer at @OttawaHospital is investigating whether blocking immune-suppressive #macrophages can improve immunotherapy effectiveness against #glioblastoma. ๐ง
Learn more: https://t.co/9OLSWyPp01
๐ง Researchers with Mathilde Bizou combined spatial transcriptomics with region-resolved endothelial single-cell RNA sequencing in the postnatal mouse brain to map cortical and thalamic neurovascular unit communication dynamics.
@NatureComms | https://t.co/zvoJdud2Pn
๐ง Scientists tested whether ferroptosis-related vulnerability contributes to the regulation of hippocampal neural precursor cells and their progeny.
@CellStemCell | https://t.co/ZMmlkSeVHF
Amir Hossein Mansourabadi and scientists at @uOttawa uncovered a bidirectional crosstalk between Oncostatin M receptor and tmCLIC1 in glioblastoma, essential for fueling its malignant growth.
@sigtrans_sttt | https://t.co/b2ZxqnnNvj
๐ง Using a human telencephalic #organoid model, researchers perform comprehensive proteomic profiling of neural stem/progenitor cells' cilia and find enrichment in GTPase signaling.
@naturecomms | https://t.co/racnBpLKed
๐ข New in @BrJCancer reports!
A study from researchers led by Dr. Nicola Tirelli at @IITalk have shown that proneural #glioblastomas exhibit greater stemness and an increased ability to develop temozolomide resistance, while mesenchymal tumors are associated with higher CD44 expression.
๐ https://t.co/4JvfccOCYs
Congratulations to Dr. Siddhartha Mitra at @CUCancerCenter on being awarded a three-year grant from the Matthew โIron Mattโ Larson Foundation for Pediatric Brain Tumors to develop CAR M therapies to treat diffuse midline #gliomas, a particularly deadly type of pediatric brain cancer. ๐ง
Learn more about his work: https://t.co/g3oaZApl0D
.@STEMCELLTech's protocol on neural organoids is live! ๐ง
Follow this step-by-step guide on processing mature neural #organoids for cryosectioning and immunofluorescence to minimize tissue damage and preserve important epitopes.
https://t.co/Ftl8UwoijH
Dr. Yolanda Prezado and colleagues demonstrate that Minibeam Radiation Therapy does not trigger canonical immunogenic cell death or cGASโSTING activation in #glioblastoma and #astrocyte monocultures, unlike conventional radiation therapy.
Learn more here:
๐ https://t.co/UQLAbS83Wk
The following review highlights cathepsins as emerging biomarkers and therapeutic targets in glioblastoma, summarizing current research and future directions for clinical application.
๐ https://t.co/LcMQ22dRZh
In this @NatureComms study, scientists develop a synthetic foldamer that stabilizes transient helical regions in Aฮฒ, reducing aggregation and improving pathology in #Alzheimers disease models.
๐ https://t.co/ZJT1G2HRAe
๐ฌ Researchers led by Dr. Luca Lo Piccolo identify a pyrazolopyridine alkaloid that reduces neuronal ER stress and improves age-related decline, highlighting a potential strategy for #neurodegenerative disease intervention.
๐ https://t.co/vN6nj4aZha
Scientists in the lab of Dr. Ilyas Singeรง at @ncats_nih_gov have developed human iPSC-derived #CerebellarOrganoids that model cerebellar development and #FriedreichsAtaxia, enabling disease studies and therapeutic testing. ๐ง
Read the study in @CommsBio: https://t.co/GxPFqo6Chk
As brain cells age, they often make mistakes when processing their genetic instructions. This creates #RNAPollution, which accumulates over decades, making the brain highly vulnerable to neurodegenerative diseases.
Researchers at @UCSDMedSchool, the @salkinstitute, and @sbpdiscovery have received a $13M award to investigate how to reverse age-related neurodegeneration by eliminating RNA pollution in aging neurons. ๐ง
Learn more: https://t.co/xmJ9ot5SrJ
Check out this new study from the lab of Dr. Dimitra Thomaidou! ๐
It shows that TET1 and LIN28A are key regulators that enhance miR-124/ISX9-driven astrocyte-to-neuron reprogramming and #NeuronalMaturation.
Learn more: https://t.co/cwlS5OdAxM
A team of researchers at @UCSDMedSchool, @salkinstitute, and @sbpdiscovery have been funded to investigate how to reverse age-related #neurodegeneration by eliminating what the researchers call "RNA pollution" in aging neurons.
The ultimate goal is to develop new therapies to protect against neurodegenerative diseases.
๐ง https://t.co/xmJ9ot5SrJ
Excited to support the 5th ALS Drug Development Summit, June 2-4, 2026 in Boston!
Join leaders from Takeda, Biogen, Novartis, Eli Lilly & AbbVie with expert speakers advancing the next generation of ALS therapies.
Save 10% with code SSN10 | Learn more: https://t.co/xqCje3B9B3
Led by Drs. Donovan Pineau and Jean-Philippe Hugnot, researchers show that EDNRB-dependent endothelin signaling reduces glioma cell proliferation while driving proneural-to-mesenchymal transition and tumor plasticity.
Learn more here:
โถ๏ธ https://t.co/VGom0iHUJK
Modeling glioblastoma relapse in vitro!
Scientists explore the spectrum of in vitro models from 2D cultures to organ-on-chip systems, to better study #glioblastoma relapse and therapy resistance.
Learn more here:
๐ https://t.co/F2kofjm6gY