Neural Cell News

An online resource for the neuroscience research community. Part of the @STEMCELLTech Science News service.

[Neural Cell News @NeuralCell]

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https://t.co/0ARdMWXNoz

[Neural Cell News @NeuralCell]

💡Scientists from @hkust established the common FAM193B-CCG repeat as an Alzheimer’s disease (AD) risk genetic factor and highlight the contribution of common #StructuralVariants to AD #heritability.

@NatureNeuro | https://t.co/s4ubtT9V32

[Neural Cell News @NeuralCell]

In this @NeuroCellPress article, scientists identify μ-crystallin-expressing #astrocytes as modulators of #Huntington’s disease pathophysiology and suggest that restoring μ-crystallin could be beneficial in early disease stages.

#OpenAccess 🔗 https://t.co/8y0YNsAiGU

[Neural Cell News @NeuralCell]

🧠 This study in @CellCellPress found that receptor protein tyrosine phosphatase sigma is the host factor mediating #TetanusNeurotoxin trafficking into the #CNS!

Congratulations to first authors Pengsheng Chen and Huan Wang, and their team!

#OpenAccess🔗 https://t.co/ukmqjMXR7A

[Neural Cell News @NeuralCell]

Researchers including Zhi Geng, Cheng Yuan, and Zeying Yua integrated multi-omics bioinformatics analyses with in vitro and in vivo functional experiments to investigate the role and mechanism of nucleoporin 35 (NUP35) in #glioblastoma glycolytic reprogramming. 🧠

Learn more: https://t.co/zey5s4UZ1n

[Neural Cell News @NeuralCell]

Gabriel Said, Adelino Sanchez Ramos da Silva, and Guilherme da Silva Rodrigues examine evidence connecting exercise, DNA methylation, and Alzheimer's disease (AD), with emphasis on AD-related loci and on the possible intergenerational implications of parental exercise. 🏃

Learn more: https://t.co/UNfzJWJjzq

#OpenAccess

[Neural Cell News @NeuralCell]

This @NatureGenet study reports a single-cell atlas of alternative polyadenylation of the aged human brain 🧠 across 2 million cells from 379 human postmortem brains across individuals with and without #AlzheimersDisease.

Don't miss it: https://t.co/aShfJBTZ9z

[Neural Cell News @NeuralCell]

🚨 A new study published in Advanced Science (@AdvPortfolio) uses 3D bioprinted-spheroids to assess blood–brain–tumor barrier penetration by anticancer drugs and their effects on #glioblastoma.

📑 Read the #OpenAccess article: https://t.co/Ajbh9oPWbh

[Neural Cell News @NeuralCell]

🧠 Read this #OpenAccess review examining midbrain organoid-based #ParkinsonsDisease modeling through a concept-driven lens: https://t.co/3dABUrCfEM

[Neural Cell News @NeuralCell]

Limonin ameliorates hyperuricemia-induced cognitive impairments, attenuates neuropathological alterations, modulates microglial polarization, and rescues neuronal apoptosis by targeting the HIF-1 pathway.

Read the study: https://t.co/mWddoQdWLw

Led by researchers at Southern Medical University and affiliated institutions.

#CognitiveImpairment #Neuroinflammation

[Neural Cell News @NeuralCell]

In a mouse model of ischemic stroke, a novel multifunctional nanoplatform (RM@HPAN) targeted ischemic brain regions, reduced infarct volume from 29.4% to 3.8%, improved neurological scores, and suppressed oxidative stress and inflammation.

Read the study: https://t.co/H38jj0iCjC

Led by first author Shaofa Li and corresponding authors Lanqing Meng and Tong Li.

#StrokeResearch #Nanomedicine #Neuroscience

[Neural Cell News @NeuralCell]

Results from a new study in @Dev_Cell provide evidence that species-specific regulation of proteasome-mediated proteolysis influences the timing of neural development and suggest that evolutionary tuning of proteasomal activity contributes to differences in embryonic developmental pace.

Read more about the findings here📕 : https://t.co/Y5vVHVYdIg

[Neural Cell News @NeuralCell]

New study in @CellPressNews: research findings unveil a mechanism linking cancer metabolism with cancer neuroscience and leverage human genetics to nominate gluanidinoacetate synthesis as a target in #gliomas.

Read more here: https://t.co/nBs4R0f7H6

#CancerResearch #Neuroscience

[Neural Cell News @NeuralCell]

Findings from a new @NeuroCellPress study define inhibitory input as a suppressive component of the #glioma ecosystem and suggest that strengthening inhibitory tone may offer a therapeutic strategy.

Read more here📕: https://t.co/TZS06q3Kgt

[Neural Cell News @NeuralCell]

🚨 New study in @CellCellPress unveils a mechanism linking #cancer metabolism with cancer neuroscience and nominates guanidinoacetate synthesis as a treatment target in #gliomas!

Read the full #OpenAccess article here: https://t.co/Exn8Dw0xSQ 🧠

[Neural Cell News @NeuralCell]

A new study reveals a hypothalamic-brainstem circuit linking acute stress to feeding suppression and gastric dysfunction.

Read the paper: https://t.co/uDg1dZ2kC0

Led by first author Dan Dai and corresponding authors Jinfei Ni and Shumin Duan at @FudanUniv and Zhejiang University.

#Neuroscience #StressResponse

[Neural Cell News @NeuralCell]

Scientists from @Stanford define the architecture of the mouse serotonergic projectome! 🤯

They show organization by functional relatedness rather than the physical proximity of targets. Published in @CellCellPress: https://t.co/m3DK0a0TlU

[Neural Cell News @NeuralCell]

.@US_FDA approved Enigma Biomedical's TAUKLARIFY™ for use in patients being evaluated for #Alzheimers! 🧠

Press release 👉 https://t.co/R2rEN0zNST

[Neural Cell News @NeuralCell]

Scientists from @UofCalifornia and @Princeton developed a fluorescent bifunctional reporter that can track estrogen response dynamics in #neurons!🧠

Read more here 👉 https://t.co/zi7xAADf7x

[Neural Cell News @NeuralCell]

Researchers have defined the spatial + molecular determinants of malignant synapses by analyzing intact human #glioblastoma specimens. They revealed enrichment of synapse-like structures and synapse-associated gene programs at the tumor–brain interface.

🔬https://t.co/J0oKQ3wM27

[Neural Cell News @NeuralCell]

Yale School of Medicine (@YaleMed) has received a grant of nearly $25 million from the Aligning Research to Impact Autism to map human brain development and investigate how and when autism diverges from typical development.

📰 https://t.co/if1QnTVUqA