Adora Cheung

welcome to the wrong timeline

[Matt Krisiloff @mattkrisiloff]

I’m so excited to share this update on @Conception –

We’ve generated the first early human eggs derived from stem cells.

This is a big deal -- the potential to redefine fertility is real.

[DOC NYC @DOCNYCfest]

You. On stage. Pitching your doc to the people who greenlight, fund, and distribute films...This is DOC NYC PRO's Pitch Day!

Co-presented by @outlierfilmfund. Submissions close August 7.

Apply: https://t.co/16hiKAcsce

[Christina Cacioppo @christinacaci]

It took us two years to grow from $10 mm to $100 mm in Annual Recurring Revenue and 15 months to reach $200 mm. Nine months later, we crossed $300 mm. Vanta’s growth rate increased each of the past four quarters – compounding really is the eighth wonder of the world!

“But wait,” you might be thinking. “How does a software company founded before 2022 *increase* its growth rate?” Narrative violation!

[Adora Cheung @nolimits]

starting from behind

[Aaron Harris @harris]

Every VC likes to pretend their companies will IPO.

This has real implications.

To quantify their potential investment opportunity VCs match a startup to similar public companies. This helps inform the current round valuation.

Unless of course it is a super hot round. Then nothing matters.

We build a tool to help founders get ahead and shape the public comp narrative, Public Comps, now in the Venture Codex. Link next.

[Instalab @getinstalab]

Most people taking GLP-1s unintentionally under-eat protein because their appetite is so suppressed. And without the right strategy, you can lose more muscle than you need to.

The clinical data points to three key levers to maintain muscle mass:

1. Protein intake. Aim for 1.0–1.5 g/kg/day. In one 12-week study, GLP-1 users who hit these targets with exercise lost 7.4 kg with zero fat-free mass loss.

2. Resistance training. Research shows that without strength training, extra protein just gets stored as fat. Aim for 2-3x/week covering major muscle groups.

3. Track your body composition. A DEXA scan before starting (and periodically during) gives you real data on whether your approach is working.

The bottom line: GLP-1 muscle loss is real but manageable, especially if you’re proactive.

https://t.co/4LXPHBSygI

[Aaron Harris @harris]

We just made a major upgrade to Venture Codex.

143k+ funding rounds.

88k+ companies.

53k+ investors.

163 countries.

That’s 15× more data to help founders see how capital is actually raised.

Link next

[Instalab @getinstalab]

Absolutely. Most people don't realize how much sleep affects fat / muscle loss.

In research, cutting sleep from 8.5 hours to 5.5 hours per night during calorie-restricted diet reduced fat loss by 55% and increased lean mass loss by 60%. More hunger; less fat oxidation:

https://t.co/LbT8KN5DqQ

[Instalab @getinstalab]

Repatha (evolocumab) is far more powerful than statins alone. When added on top of statin therapy, it can lower LDL cholesterol by ~60% and reduce major cardiovascular events by ~15%. As its price tag continues to drop, we’re excited to see how many lives this medication will save.

[Instalab @getinstalab]

Your APOE genotype plays a critical role in how your brain processes fats and repairs neurons. Each of us inherits two copies of this gene, one from each parent, and the specific combination we carry (ε2, ε3, or ε4) can influence how our brains age over time.

Certain APOE variants, such as ε4, are linked to a higher risk of Alzheimer’s disease. But your genes do not necessarily determine your destiny. Many people with ε4 alleles never develop dementia, especially when they take proactive steps to protect their brain:

- Regular moderate-to-vigorous physical activity
- Mediterranean-style diet
- Quality time with family and friends
- Consistent, high-quality sleep
- Avoid smoking
- Limit alcohol intake
- Manage risk factors like blood pressure and apoB

Understanding your genotype empowers you to take control of your brain health and make informed, preventive choices. If you’d like to learn more about your APOE status, schedule a blood test today: https://t.co/paSPFjamLT

[Instalab @getinstalab]

If you're 40 or older and haven't had a CAC scan, get one. It's the most definitive way to see how much plaque has already clogged your heart's arteries.

ApoB predicts future risk.

CAC reveals existing risk.

https://t.co/rlAmzdjRTk

[Eric Topol @EricTopol]

A new way to get very early detection of colon cancer using cell-free RNA (instead of DNA) @NatureBiotech
https://t.co/S5XErpdPTB

[Aaron Harris @harris]

I'm rewriting the Series A Guide.

Markets have changed in the last five years and advice should change along with it.

If you've raised an A in the last 6 months, I'd be grateful for 30 minutes of your time.

DMs are open.

[Scott Gottlieb, MD 🇺🇸 @ScottGottliebMD]

An important step towards helping Americans incorporate healthful seafood choices into their diets in a sustainable way. This clearance demonstrates the viability of the regulatory pathway that the FDA has created for these products

https://t.co/mOLa5FM4Oo

[LGAjots @LGAjots]

What if shopping felt like Pinterest, but worked?

You can now vibe shop for your home — and our AI saves you hundreds (sometimes thousands) of dollars.

So proud of the team that made this real.💪

https://t.co/RUeDJuKyc3

[Tim Urban @waitbutwhy]

One of the most egregious examples of paid-for politicians forcibly holding back a wildly beneficial technology to protect corporate interests. It is an affront to freedom, stripping citizens of the option to spare animals and the environment in their meat consumption.

[Instalab @getinstalab]

If you're taking creatine, monitor your kidney function with a blood test called Cystatin C, which is any case a much better reflection of kidney function than creatinine regardless of supplementation or not.

[Teal Health @TealHealth]

We are excited to announce the Teal Wand is FDA-approved and coming soon! For the first time, women will be able to collect a sample at home to screen for cervical cancer. Same test and accuracy as the doctor’s office, but no speculum required. https://t.co/qZjVyuXpna

[NIH @NIH]

Today, NIH announced a new initiative to expand innovative, human-based science while reducing the use of animals in research. This aligns with @US_FDA’s initiative to reduce testing in animals. https://t.co/i4QH6FwqlC

[Adora Cheung @nolimits]

Notice from ConsumerLab on Athletic Greens (AG1) and potential heavy metals content.