Euan Arnott

[Euan Arnott @Nucleocapsoid]

Pinning this to help convert between multiple alternative numbering systems in use for influenza H5N1 hemagluttinin.

[Bloom Lab @jbloom_lab]

In addition, we have made a page to help convert between the many confusing numbering schemes used to name HA mutations: https://t.co/IkizgoNIZ7

(Throughout we use H3 numbering, but other studies use other schemes)

[Euan Arnott @Nucleocapsoid]

@danwalker9999 @HelenBranswell Of course - but corrections always helpful in what is still confusing situation for all.

So glad Bunia now has KH Medical PCR machines running PCR test specific for Bundibugyo & so has caught up on test backlog - although central testing still means delays if you're in Mongbwalu

[Euan Arnott @Nucleocapsoid]

That clarifies the situation.

Thanks.

[Daniel A. Walker 🇨🇦🇺🇦🇬🇱🌻😷💉🚴🏻 @danwalker9999]

@HelenBranswell NOT 633 confirmed & suspect cases
344 confirmed cases (cumulative)
+
116 suspect cases under investigation
=
460 confirmed + suspect cases
173 patients in isolation-hospitalization is a separate statistic: a subset of confirmed cases and a subset of suspected cases.

[BEACON @beacon_bio]

03 Jun 2026 – Bundibugyo virus disease outbreak: DRC cases rise to 344; Mambasa newly affected; Uganda expands contact travel restrictions

Read more at: https://t.co/XTw14XK3GU

[Euan Arnott @Nucleocapsoid]

@danwalker9999 It would be good if the original Post were corrected by @HelenBranswell - I presume that is what you mean?

[NYMC_460 @onodera460]

6/02日、シンガポールから116例 (対象期間: 5/18~5/25)追加報告。
NB.1.8.1系統の感染が拡大傾向にあり、中でもPQ.16.1.1がその大部分 (76例中55例、72％)を占めている。RF.5は急減し、BA.3.2は横ばい状態。なお、第22週のデータは5/25日に報告された症例(22例)のみ 。

[Euan Arnott @Nucleocapsoid]

Household secondary attack rate for Ebola typically >10% historically.

With around 2000 "missing" contacts, even just 5% onward spread would be 100 extra chains of transmission.

Those on ground know contact tracing is key.

@HelenBranswell also knows...

[Patient LIGODI @ligodipatient]

Budibungyo/RDC: 4010 contacts suivis, mais seulement 1760 vus. Principale blocage en Ituri, forte résistance communautaire, renseignent les documents de la riposte.

[Euan Arnott @Nucleocapsoid]

@declanwalsh May I enquire to clarify: did that poor 5-year-old actually receive a positive Ebola PCR test?

Fever (always) & nosebleed (10%?) does occur with typhoid also - so it was unclear from clinical description whether he had Ebola at time of original filming.

So pleased he's better!

[Declan Walsh @declanwalsh]

Great and tragic news at once.
Emmanuel, the 5-year old featured in this report, has since recovered and left the Ebola ward, his father told me.
But the lab technician I met in the next ward deteriorated and died last night. His name was Bienfaits.
https://t.co/ggpolsFgAY

[Ian M Mackay, PhD (he/him) @MackayIM]

One PCR test in the DRC labs is a rapid test from KH Medical in South Korea, relying on the RADIONE extraction & amplification device (1 or 4-sample versions; 60min to result). It uses a range of their kits.
🧬 https://t.co/yYRQXybTRt
🧬 https://t.co/lqi05rga0F

[Patient LIGODI @ligodipatient]

Les telecoms dans la riposte…

On parle beaucoup des vaccins, des médicaments, des centres de traitement. Moins de ça : dans les zones de santé autour de Bunia, il n'y a souvent pas de réseau fiable.
Un document opérationnel humanitaire daté du 1er juin le confirme. La couverture réseau en Ituri est concentrée autour du centre urbain de Bunia. Elle chute rapidement dès qu'on s'éloigne vers les zones de santé périphériques (Mongwalu, Nyankunde, Rwampara exactement là où l'épidémie est la plus active). Le réseau 3G/4G qui existe en ville est fragmenté, dépendant d'un petit nombre d'antennes, vulnérable aux coupures. Et l'électricité est instable dans une grande partie de la région.
Le Cluster Logistique et Télécommunications d'Urgence travaille à étendre la connectivité vers ces trois hubs. C'est prévu. Mais ça prend du temps. Et pendant ce temps, la riposte fonctionne avec des trous dans sa chaîne d'information.
PL

[Helen Branswell 🇨🇦 @HelenBranswell]

Wondering where things stand with MappBio's MBP-134 #Ebola monoclonal antibody? The company posted on it today on LinkedIn. And @PeterHorby said Oxford's Pandemic Sciences Institute is working hard to get MBP-134 into a clinical trial in the outbreak zone. https://t.co/1XtbFH1FJg

[Euan Arnott @Nucleocapsoid]

@HelenBranswell I think this issue of non-confirmed cases being apparently split into two different categoies may have been what you were referring to in a previous Post (below)?

Most outlets seem to be ignoring the "Isolated" figure completely in their discussions.

https://t.co/TzPgTaA3uX

[Helen Branswell 🇨🇦 @HelenBranswell]

Nice to see daily numbers out of DRC on the #Ebola outbreak but the new presentation is a bit confusing. Not clear why suspect cases are divided into 2 categories. Also, reporting only the percentage of contacts being followed masks the number identified, which has been low.

[Euan Arnott @Nucleocapsoid]

@HelenBranswell How do you get to that 633?

I'm confused by separate listing of "Suspected" & "Isolated" cases - can you help us understand more precisely if these are entirely different patient groupings?

Many reports just add "Confirmed" to "Suspected" - and so get *lower* number than 633.

[Reuters @Reuters]

Global health organization CEPI will give roughly $60 million to Moderna and two other groups to accelerate the development of shots against Ebola Bundibugyo, the deadly virus that has swept through eastern Democratic Republic of Congo https://t.co/wlgT0gQV4c

[Daithí Mac Cathmhaoil @DrDaveCampbell]

@wesstreeting @LeonieGreene I’ve posted this a few times as it still keeps me awake at night. Perhaps there was a time before all this began, when I naively believed a human being couldn’t deliberately & coldly shoot a child, except a rare aberration, some kind of psychopathic monster, but I was wrong.

[K-in-CT 😷😷😷 @KinCONN]

#ebola
⚠️
➡️🇨🇩 DR Congo re-opens airport at centre of Ebola outbreak

- Democratic Republic of Congo has re-opened the ‌airport in the capital city of the province hit hardest by the ongoing Ebola outbreak, a government statement said, reversing a move that some residents said had cut them off from critical supplies.

- The government in Kinshasa ➡️ announced ​last month that it was suspending passenger flights to Bunia, the main airport in ​Ituri, where the first Ebola cases were confirmed. ➡️ Humanitarian and medical flights continued ⁠subject to approvals.

- In a statement published late on Monday, ➡️ Congo's transport ministry said ➡️ conditions were now ​in place "to allow a gradual and safe resumption of air transport activities" and that the airport ​would re-open immediately.

- The ministry said all passengers would have their body temperatures screened before boarding and on arrival, that passengers were required to wash their hands before boarding and that any passenger with a fever would not be allowed to board.

- The decision to re-open the airport in Bunia followed a visit from WHO Director-General Tedros Adhanom Ghebreyesus, who told reporters on ​Monday he saw some ​encouraging signs in the ⁠response, including five certified recoveries. But he also noted the need to ramp up testing and treatment capacity and promote trust in health workers.

- There ​have been 321 confirmed Ebola cases including 48 confirmed deaths, according to the ​latest government ⁠figures on Monday.

- ➡️ Ebola has reached 15 of 36 health zones in Ituri, and cases have ➡️ also been reported in North and South Kivu provinces and in neighbouring Uganda.

- ➡️ The International Rescue Committee warned on Monday that ⁠the ​outbreak was probably significantly larger and more advanced than official ​figures suggested.

- The aid agency said the virus might have been spreading for up to three months before the first official ​cases were detected in mid-May.

https://t.co/KnOdfoNDb8

[Euan Arnott @Nucleocapsoid]

@NickRicci5 @BNOFeed They have more likely temporarily run out of KH Medical RADI ONE PCR cartridges (or similar analysis issue) - this is about testing issues rather than obfuscation.

[BNO News @BNOFeed]

Daily Ebola update:

- Cases: 359 (+7)
- Deaths: 61 (+12)

[Dr. Ali Khan @DrAliSKhan]

.@WHO is refining suspect case numbers with better testing and maps, but true control depends on a strict sequence of public health indicators. We aren't winning until:
ZERO new sick health workers (currently ~20% of cases)
100% of burials safe
100% of contacts monitored
ALL new cases emerge only from known, quarantined contacts.
https://t.co/xwz85nXc6y

[Euan Arnott @Nucleocapsoid]

@KinCONN If IAVI candidate (rVSV Bundibugyo) is at *most* advanced stage - having completed animal trials in NHP's - why is its timeline to Phase-1 human clinical trial >6m, whereas Oxford one (ChadOx BDBV) is suggested to be only 2m from Phase-1 despite no animal pre-clinical AFAIK??