PA Champagne

Assistant Professor @NJIT | Synthetic, physical, and computational organic chemistry | Québécois in New Jersey

[PA Champagne @PAChampagne]

Glad I had the opportunity to contribute to this work! Check out the preprint to learn more about the ncuelophilic reactivity of zinc persulfide complexes.

[Pluth Group @PluthGroup]

New @ChemRxiv preprint:
Closing the H2S/NO Signaling Loop: Nitric Oxide Regeneration by a Synthetic Zn2+ Persulfide via Transnitrosation and Nitrite Reduction
Great work @SayanAtta95, @keyanl10, & Alex! Computational work by @PAChampagne.
https://t.co/IAwCLlZtcy

[PA Champagne @PAChampagne]

@christine_m_le @iupac2025 Congratulations Christine!

[PA Champagne @PAChampagne]

Congratulations Diana!

[LatinXChem @LatinXChem]

Congratulations to @DianaBagatella from @NJIT on winning first place in the #LatinXChemComp category.🏆We congratulate Diana on this remarkable achievement. Diana has won a €250 book voucher from @digital_rsc @PCCP. Stay tuned. We will soon announce the winners of #LatinXChemEdu

[PA Champagne @PAChampagne]

Does anyone know of a good electrical physics primer for organic chemistry students who are about to learn mass spectrometry and NMR but that have yet to take the full physics course? Think ions bending in a magnetic field, magnetic shielding from electrons, etc.

[Diana M. Castañeda Bagatella @DianaBagatella]

Hi @LatinXChem, I'm glad to present my work on "DFT investigations of the enantioselective phase-transfer-catalyzed aza-Michael cyclization of urea" at #LatinXChemComp.

Thank you for the opportunity.

#LatinXChem24 #Comp007 #DFT #Catalysis #OrganicChemistry #Chemistry #Compchem

[PA Champagne @PAChampagne]

Update alert for Visualize Organic Chemistry! We've added an example of stereospecific SN2 reactions, which can also serve as an exercise on stereochemistry (https://t.co/g3iSeLcDJR) and SN1 reactions. I hope these can be helpful if you're teaching Organic this semester!

[PA Champagne @PAChampagne]

@LukeshGroup @NIH @NIGMS Congratulations! I look forward to reading those future papers!

[Abearica @abearicaonline]

@MalwareJake @CrowdStrike Here is a great how to fix your computer

We have been running around the office all night fixing these darn things.

These steps work.

[J. Am. Chem. Soc. @J_A_C_S]

Transpersulfidation or H2S Release? Understanding the Landscape of Persulfide Chemical Biology | Journal of the American Chemical Society @PAChampagne @NJIT @PluthGroup @UO_Research @uoregon #Transpersulfidation #H2S #Persulfide #ChemicalBiology
https://t.co/4o2MBYXGC9

[PA Champagne @PAChampagne]

Very fun collaboration with the @PluthGroup on the intrinsic reactivity of persulfides, check it out!

[Pluth Group @PluthGroup]

When do persulfides transfer a persulfide group to a thiol and when do they release H2S? Our collab w/ @PAChampagne in @J_A_C_S provides new experimental & computational insights. Great work Kaylin & Jyoti on working out this chemistry! https://t.co/3lBWCD6Smr

[PA Champagne @PAChampagne]

So happy that our study found its place in JOC. Polysulfide chemistry is not even close to being understood, I'm excited for what's to come!

[J Org Chem/Org Lett @JOC_OL]

Polysulfides in the Gewald synthesis of aminothiophenes are under complex equilibria and decompose in a thermodynamically-controlled process; a computational study by @PAChampagne from @NJIT is published online now at #JOrgChem. Read it here ⤵️ https://t.co/UpMZxhH8lM

[PA Champagne @PAChampagne]

@RacicotLeanne That's for my home printer that's 14 years old though so no complaints. Too bad Samsung sold their printer division to HP 🤮

[PA Champagne @PAChampagne]

Why are printers still so finnicky in 2024? Here's the content of my black magic text file to make mine work:

Computer on
USB connected
Turn off printer with power button
Unplug, then replug printer
Turn on printer
Wait for the rollers to activate and hear 3 beeps
Print!

[PA Champagne @PAChampagne]

Our paper is out! I hope it can be interesting and helpful for those who work with reactions leading to cyclubutanes, such as electrophilic openings of bicyclobutanes.

[J Org Chem/Org Lett @JOC_OL]

Computational insights provide predictability for substituent effects on mixtures of cyclopropylcarbinyl, bicyclobutonium, homoallylic, and cyclobutyl cations. A study in #JOrgChem by @PAChampagne @NJIT. Check it out: https://t.co/ha895RKXJJ

[PA Champagne @PAChampagne]

@ndchiappini @NJIT Polysulfides themselves are also good nucleophiles but for them opening sulfur allotropes is thermodynamically unfavorable. It might be kinetically plausible as a way to exchange between polysulfide lengths, but probably not a major path. Overall, really cool and complex!

[PA Champagne @PAChampagne]

@ndchiappini @NJIT That's a really good question, and honestly it's hard to predict. Small sulfur allotropes are SUPER electrophilic, so they will react faster than almost any other intermediates with the nucleophiles. Kinetically they are more likely to react with the carbon Nu than a polysulfide.

[PA Champagne @PAChampagne]

Ever wondered how organic transformations using elemental sulfur can be even be selective? Check out our latest pre-print on the mechanism of the Gewald synthesis of thiophenes, where we (once again) try to make some sense of complex mechanisms! https://t.co/pa2DypaDDW

[PA Champagne @PAChampagne]

So happy about this collaboration with @PluthGroup! Slowly but surely we will learn enough about reactive sulfur species to start controlling their reactivity!

[Pluth Group @PluthGroup]

New computational & experimental @ChemRxiv preprint w/ @PAChampagne on understanding transpersulfidation vs H2S release from persulfides! Includes direct measurement of transpersulfidation between small molecule RSH/RSSH. Great work Kaylin & Jyoti! https://t.co/reYRApR5UZ

[PA Champagne @PAChampagne]

@FlorisButtard @BessetTatiana @AdvSynthCatal @Ma_ivana Félicitations Floris et toute l'équipe!