Pacome Prompsy

Bioinformatician, Data Engineer & Data Analyst at Institut Curie

[Pacome Prompsy @PPrompsy]

Article published in NAR Genomics and Bioinformatics. Please try it out on https://t.co/1KzyrDrLJY , and post issues if encoutering any bugs.
Happy to take any feedback !

[Pacome Prompsy @PPrompsy]

Pleased to present IDclust, a tool to automate and ease exploration of single-cell datasets.
IDclust recursively clusters and find differential features between clusters until no more differences are found.
With @MelissaSaichi @gama_search @VallotCeline https://t.co/gYpA0hq8do

[Pacome Prompsy @PPrompsy]

Additionnally, IDclust creates a hierarchy of parents and child cluster, and plots tree-like networks revealing potentially meaningful relationships between clusters.

[Céline Vallot @VallotCeline]

📝Epigenomic heterogeneity as a source of tumour evolution

Just out in Nature Reviews Cancer - a piece we wrote with @MatLupien and @MartheLaisne, a fantastic team work and such a pleasure to exchange & confront ideas on cancer epigenetics.

👉https://t.co/3ChmgZqHTU

[Céline Vallot @VallotCeline]

Our team is expanding, we are looking for a new collaborator - Computational Scientist (IR) - to join us at @institut_curie @CNRSbiologie @Unit3244_ICurie . Exciting single cell cancer datasets to analyse and a great opportunity for a permanent position. Postdoc, PhD or IR apply

[Felix Raimundo 🧬🇪🇺/acc @gama_search]

Our paper with @jeanphi_vert and @VallotCeline on how best to analyse single-cell histone modifications is finally out on Genome Biology:

https://t.co/twwjevn0wP

See this thread for a presentation of the paper https://t.co/DipgMxsPTl

[Céline Vallot @VallotCeline]

MAYA algorithm for scRNA is out in @NatureComms - it detects common expression programs across tumor cells from various cancer patients @onebiosciences @institut_curie

[Felix Raimundo 🧬🇪🇺/acc @gama_search]

"Best practices for single-cell histone modification analysis" w/ @VallotCeline @jeanphi_vert and @PPrompsy.

We identify how to analyze scCUT&Tag, from matrix construction, QC, #cells, up to dimension reduction.

paper: https://t.co/PC0XSRBPmC
code: https://t.co/wLaWLGNRVA

[Institut Curie @institut_curie]

#Recrutement
Le Centre de recherche de l'Institut Curie recrute un #DataAnalyst/ingénieur de recherche (H/F) pour l'étude de données multi-omiques #singlecell, au sein du laboratoire de @VallotCeline.

➡️Pour postuler : https://t.co/UzWejbry2t

[Céline Vallot @VallotCeline]

Interested about epigenomics, want to learn how to analyze epigenomes at single-cell resolution? Join us!!

[Morillon’s lab @LabMorillon]

The Morillon's group is recruting a 3 years post-doc to reveal what you never dare to ask on cancer dark transcriptome invading the immune response cells, with our fantastic collaborators C. Théry lab and prof C. Le Tourneau. @institut_curie and @Institut_cancer

[Michael Meers @mpmeers]

Today there's a revised version of the MulTI-Tag manuscript out on bioRxiv--dig in here for a brief summary of some new improvements/data and general thoughts on multifactorial chromatin profiling in single cells 1/14 https://t.co/BxzubojAG9

[Céline Vallot @VallotCeline]

1/5 Our manuscript on early breast tumorigenesis is out on biorxiv https://t.co/zatWAfDRWb, @institut_curie @INSB_CNRS, impactful work led by @CamilleLandrag3 and @MelissaSaichi, great collaboration with @HeleneSalmon

[Céline Vallot @VallotCeline]

Merci la @lamethodeFC @NatachaTriou @NicoMartinFC pour cette mise en lumière de nos travaux sur le rôle des modifications épigénétiques dans la réponse à la chimiothérapie @institut_curie @INSB_CNRS

[Céline Vallot @VallotCeline]

Our study on the role of repressive histone mark H3K27me3 in determining cell fate upon chemotherapy treatment is out! Congrats to Justine Marsolier, @PPrompsy and all authors and collaborators E.Marangoni @Perielab1 @institut_curie @INSB_CNRS

[Céline Vallot @VallotCeline]

Together with @MathildeJDura & @DeborahBourchis on the upcoming issue of Nature Genetics, all the way from spermatogenesis to cancer @institut_curie @INSB_CNRS

[Nature Genetics @NatureGenet]

Out now! H3K27me3 conditions chemotolerance in triple-negative breast cancer (Marsolier et al.) https://t.co/9yVadcTxyF

[Pacome Prompsy @PPrompsy]

@CamilleLandrag3 @VallotCeline Thank you Camille ! 😀👍 Congrats to everyone :)

[Céline Vallot @VallotCeline]

We are looking for a talented postdoc to work on the evolution of epigenomes in the early steps of breast tumorigenesis in vivo #epigenetics #singlecell #cancerresearch - ERC-funded project, apply at https://t.co/xefJQC94dl