PREDiCT - Models

Uniting preclinical, translational and discovery scientists. Tweeting about innovations in applications of models in R&D. Discover the upcoming PREDiCT events.

[StemoniX (acquired by AxoSim) @StemoniX]

Visit us @PREDiCT_Models Summit in Boston this week and learn how StemoniX products are being used by some of our collaborators! We hope to see you there. Contact us at [email protected] to set up a meeting!

[PREDiCT - Models @PREDiCT_Models]

Excellent work from Mathew Garnett's @sangerinstitute group in oesophagal adenocarcinoma organoid cultures to study clonal evolution and precision therapeutics
https://t.co/tJQzno1syv

#cancerresearch #drugdiscovery #organoid #organoids #3dtissue #3dmodel #microphysiological

[EllisLab_ @EllisLab_]

Utilizing 3D organoid culture to predict the metastatic potential of primary prostate cancer - functional assays for patients @PCF_Science @soulehoward1 @UrologySBUR @gr8straj @DrChoueiri @kat_morel @CFCE_DanaFarber

[PREDiCT - Models @PREDiCT_Models]

Really interesting work using chip-based 3D models. Given the lack of predictive #models, and only 2 approved symptomatic treatments for idiopathic #pulmonaryfibrosis, clearly, this holds a lot of promise in advancing future therapies

https://t.co/jwAttVCqGf https://t.co/3LoVUBZlyO

[Sandy Williams @DrSandyWBiomed]

Love seeing all the great research outcomes from organ-on-a-chip projects: here is a recent publication from the University of Buffalo. Dr. Zhao and team simulate pulmonary fibrosis with their lung-on-a-chip system for drug testing.  https://t.co/pHWyGq8qv7

[PREDiCT - Models @PREDiCT_Models]

@lifecourse_KCL @PatxPedro @DRG_Kings @kingsmedicine @STEMCELLTech Wow !

[PREDiCT - Models @PREDiCT_Models]

Fascinating work from @wakeforest. Researchers developed a #3D #organoid model recapitulating the BBB and mimicking normal human anatomy with huge implications for #stroke research
https://t.co/S7AZSs0Zrg

[PREDiCT - Models @PREDiCT_Models]

A fascinating presentation from @dangville on the development a new #3Dmodel done in collaboration with @HemoShear for the study of #pancreatic #cancer and #NSCLC. Great to see the novel incorporation of tumor hemodynamics and biological transport #3DOncology18

[PREDiCT - Models @PREDiCT_Models]

"A model is a lie that helps you see the truth - the goal with 3D is to minimise that lie"
Asellus CEO Brett Hall & @MitraBiotech's Mark Paris explore how 3D Models are revealing molecular and phenotypic insights over 2D models.

#3DOncology18

[PREDiCT - Models @PREDiCT_Models]

Its been a fascinating morning at #3doncology concluded by the @scrippsresearch Tim Spicer on the use of #3D #spheroids models in discovery. Was amazing to not only see the progress of these platforms in automated ultra HTP formats but thier power over 2D models

[PREDiCT - Models @PREDiCT_Models]

Great presentation from @GSK's Jason Ekert exploring some of the scaling and automation challenges for #3D #tumor #spheroids. Was fascinating to see how they've informed their emerging bispecific compounds.

[PREDiCT - Models @PREDiCT_Models]

Researchers at Houston Methodist have published data on their "4D" model to show the growth of primary tumours, the formation of CTCs and formation of metastatic lesions

https://t.co/DVGJ2zvIFG

[PREDiCT - Models @PREDiCT_Models]

Jarno Drost and @HansClevers review #tumor #organoids and their utility as an alternative model for #cancerresearch in this @NatureRevCancer paper

https://t.co/oeVdQ8ZUvI

[PREDiCT - Models @PREDiCT_Models]

New precision #cancer #model combining #CRISPR & #RCASTVA delivery opens doors to personalized cancer treatment by mimicing the genetic complexity of cancer
@NatureComms
#tumormodel #preclinical #canceresearch #ResearchHighlight #PrecisionMedicine https://t.co/zPKwgJ5qy7

[PREDiCT - Models @PREDiCT_Models]

The furture of cellular generation, phenotyping and disease modelling?? #CRISPR derived #organoids https://t.co/c0E1ahR7Qe

[Wellcome Sanger Institute @sangerinstitute]

Happy 5th Birthday to Sanger's cell makers! Their expertise in #stemcells, #organoids and #CRISPR powers our large-scale projects into health and disease https://t.co/rLBMVrrapk

[Amber Tong @AmberTongPW]

"The ML models that are developed will then help guide subsequent experiments, providing a tight, closed loop integration of in silico and in vitro methods (an insitro paradigm).” @JohnCendpts - https://t.co/SdAgfFqM6r

[PREDiCT - Models @PREDiCT_Models]

Scientists from @wyssinstitute, @JanssenUS & @emulatebio publish results showing the translational potential #organonchip to better predict thrombotic side effects of drug candidates.

https://t.co/gMGv4EuKWz

[PREDiCT - Models @PREDiCT_Models]

@Roche researchers using @MIMETAS_3D microfluidic #3Dculture tech have begun to elucidate the mechanistic effects underlying diarrhea induced by anti-HER2/3 #combinationtherapy

https://t.co/cjrRFpe1LM

[PREDiCT - Models @PREDiCT_Models]

BASF signs 3D bioprinting cosmetics deal with Poietis https://t.co/JlKF7qoyQT

[PREDiCT - Models @PREDiCT_Models]

A fascinating article showing the power of patient-derived #ipsc & #organoids for disease modelling.
#kidneydisease #3dcellculture #3dmodels https://t.co/Wb9D6t04Nt

[Shuji Ogino @shuji_ogino]

we could link diet, gut bacteria and cancer;
https://t.co/GRwrOVZsTZ