Pachlopnik Lab

Our lab focuses on inborn errors of the immune system and their consequences on health. We are at the University Children‘s Hospital and University of Zurich

[Pachlopnik Lab @PachlopnikL]

@ESIDsociety @IsabelleMeyts We‘ll definitely miss you too, dear Isabelle!

[Casanova Lab @casanova_lab]

Monumental paper by Helen C. Su and collaborators, with profound biochemical, immunological, and clinical implications:
Germline mutations in a G protein identify signaling cross-talk in T cells | Science https://t.co/9tUSBBSIuK

[Prague Immunodeficiency Group @immuno_prague]

Cheers to the first global collection of clinical and immunologic findings of patients with the IGLL1 B-cell deficiency.

👉https://t.co/LeFX4ZvdIK

Thanks for your enthusiasm @PachlopnikL !!!

Proudly co-authored by Czech PID team incl. us at @immuno_prague 🙏

[Hans Clevers @HansClevers]

Looking for PhD students/postdocs for my newly opened lab at the Institute of Human Biology of #Roche in Basel. We work on human lung, liver and gut #organoids. Send email + CV + motivation letter to [email protected] with header #IHB https://t.co/5Ki03fy4NH

[Pachlopnik Lab @PachlopnikL]

@_TMarchetti Tommaso, your dedication and hard work in harnessing T cell exhaustion in HLH have resulted in significant progress. I am confident that your contributions will have a lasting impact. Well done!

[Tommaso Marchetti @_TMarchetti]

Could inducing cell exhaustion be the solution to stop deadly hyperinflation?

We found that directing IL-2 to overstimulated CD8 T cells triggers exhaustion and prevents lethal inflammation!

#IL2 #CD8Tcell #HLH

https://t.co/X8tlYxllAs

[Pachlopnik Lab @PachlopnikL]

Advancement in Diagnosing Severe Hyperinflammatory Condition: innovative assay leveraging gamma delta T cells' cytotoxic granule degranulation.

https://t.co/Wjx6RWRVAj

#MedicalResearch #Immunology #HLH #Innovation #ClinicalDiagnostics #PrimaryImmunodeficiency

[Pachlopnik Lab @PachlopnikL]

Struggling with management decisions for severe T cell lymphopenia detected by newborn screening and uncertain genetic diagnosis? Dive into our publication so see how thymic organoid cultures are reshaping care:
https://t.co/erf5a4don3
Thanks for the incredible collaboration!

[Pachlopnik Lab @PachlopnikL]

@kinderimmu Congrats, dear Elena! 🎉🥳

[Arbeitsgemeinschaft Pädiatrische Immunologie (API) @kinderimmu]

The 40th API meeting concluded, filled with insightful talks and vibrant discussions on malignancy in the context of inborn errors of immunity. Thanks to our community for making it memorable in the historic venue! Excited for 2025 --> https://t.co/oYWOcukDWf! 🌟🧬#immunology

[kate sullivan @katesullimmuno]

Do you love immune dysregulation???? Of course you do! Save the date for a full day of cool cases and heat lectures. June 7 virtually. QR code for registration

[URPP ITINERARE @itinerare_uzh]

📢 Join us at the ITINERARE Symposium 2023 on Nov 30th at @UZH_en ! Explore cutting-edge rare disease research, gene therapies, and more with global experts. Register by Nov 17th - it's free! Don't miss out! 🧬🔬 #RareDisease #UZH
https://t.co/DYMMSIsbCR

[ESID @ESIDsociety]

Calling all ESID Juniors! You are invited to become a curator of the GenIA platform - a new platform that aims at integrating multi-dimensional IEI information. Becoming a curator can bring you multiple benefits. Find out more here: https://t.co/ia1V7JRiIM
#esid #iei #raredisease

[Pachlopnik Lab @PachlopnikL]

@ESIDsociety @IsabelleMeyts Very carefully setup! Worth joining!

[Kinderspital Zürich @KispiZuerich]

Für unser neues Kinderspital suchen wir zusätzliche Mitarbeitende. Zusammen engagieren wir uns für kranke Kinder und Jugendliche. Wo sonst macht Arbeit so viel Sinn? Jetzt bewerben und weitersagen: https://t.co/FEcR3YnlAI #ZusammenSindWirChampions #kispichampions

[Prague Immunodeficiency Group @immuno_prague]

Prague PID group of @2LFUK and @cktch visit to @uzh & Kinderspital Zürich @KispiZuerich for scientific/clinical exchanges and planning joint projects. Thx @PachlopnikL for unparalleled hospitality and @UniKarlova for the support. Looking forward to our exciting collaborations!

[Pachlopnik Lab @PachlopnikL]

@immuno_prague @2LFUK @CkTch @KispiZuerich @UniKarlova @annasediva @BloomfieldM_1 @Adam_Klocperk @UZH_ch Thank you so much for coming to Zurich. Very much enjoyed the inspiring discussions about PID. Looking forward to continuing our joint projects!

[Ivan Zanoni @Lo_Zanzi]

#WeekendRead! #ImmunometabolismPower! #STING can block #tumor growth independently of its capacity to drive #interferons by acting as a cell-intrinsic #metabolic checkpoint that restricts aerobic #glycolysis to favor anti tumor responses! @NatureCellBio https://t.co/zt9Zzxlbw8

[Pachlopnik Lab @PachlopnikL]

@HeldLeonhard @WehrSue I prefer, if scientists do not only share data, but also findings and insights.