Parker Lab

We’re interested in understanding how plants activate and fine-tune their innate immune responses towards invasive (host-adapted) biotrophic pathogens.

[Parker Lab @ParkerLab_MPIPZ]

https://t.co/OYTHg5KkLG

"Balanced plant helper NLR activation by a modified host protein complex"

Fine tuning of immune responses

[Parker Lab @ParkerLab_MPIPZ]

Bioinformatics and functional analysis of EDS1 genes in Brassica napus... https://t.co/3FW2d7OqWn

[JC De la Concepción @delaconcepcionj]

"Bioengineering a plant NLR immune receptor with a robust binding interface toward a conserved fungal pathogen effector"

Great work from @ZdrzalekR at @mjbanfield lab #BlastOFF

https://t.co/WbtMzJMUXJ

[Parker Lab @ParkerLab_MPIPZ]

Conifers Concentrate Large Numbers of NLR Immune Receptor Genes on One Chromosome https://t.co/ZCLS0dy1V9

[The Plant Cell @ThePlantCell]

The Plant Cell in a Nutshell: A phosphorylation module regulates soybean basal immunity https://t.co/KN4QgGillY @ASPB #PlantSci

[Yasin Dagdas @PlantoPhagy]

📢NEW #Preprint ‼️ Magnum opus of @MarionClavel4 w/ excellent help from many amazing people. Keywords: #autophagy #viruses #modified_self_recognition #immune_signaling. Please let us know what you think.🧵 summarising our key findings

[The Plant Cell @ThePlantCell]

IN BRIEF: From algae to apples: The structural and functional conservation of NLRs (Michael Busche, Bradley Laflamme) https://t.co/TKF79AKQY2 @JohnInnesCentre @Khongsam_Chia @Phil_Carella @ASPB #PlantSci

[National Academy of Sciences @theNASciences]

Congratulations Jane Parker of @mpipz_cologne, newly inducted NAS international member! #NAS161 #NASmember #genetics #plantbiology

[Cell @CellCellPress]

As part of the #50YearsofCell, our focus issue on Immunology is out! ⁠
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This issue brings Cell’s 50th anniversary celebrations straight to your lymph nodes with reviews, perspectives and more thought-provoking articles on topics ranging from innate immunity to plant immune systems, and immunological strategies for bacterial detection. ⁠
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In addition, it features research articles on the mapping of the microbiome across metastatic cancers, a time-series reconstruction of human centriole assembly and how an inhibitory ligand acts directly on CD3e to boost tumor-specific T cell cytotoxicity and limit tumor growth.⁠
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⁠To read more click here 👉 https://t.co/DWf0VlDvUt

[The Plant Cell @ThePlantCell]

The N-terminal domains of NLR immune receptors exhibit structural and functional similarities across divergent plant lineages (Khong-Sam Chia, Jiorgos Kourelis, Albin Teulet, et. al.) https://t.co/3299MzNZ6D @JohnInnesCentre @Khongsam_Chia @Phil_Carella @ASPB #PlantSci

[MPIPZ Cologne @mpipz_cologne]

📣New publication out by Schulze-Lefert and Chai @mpipz_cologne @Westlake_Uni on how phase separation plays a role in the immune system of #plants. Now published in @Nature Congratulations! 🥳👏👏 Learn more 👉https://t.co/teJ8DJsuAp #Immunology
https://t.co/EUxkv0tlAu

[Danve Castroverde @DanveC]

Substrate-induced condensation activates plant TIR domain proteins @Nature

https://t.co/l66eJ0Nh7a

[Science Magazine @ScienceMagazine]

A plant immunity protein interacts with a fungal cell wall–degrading enzyme to create immunogenic compounds, according to a new study in Science.

Learn more ⬇️
📄: https://t.co/K1KQYnNNVk
#SciencePerspective: https://t.co/Ha4twqlAHX

[Bruno Ngou @BrunoNgou]

Our story on the origin and evolution of plant PRRs is out @NatureComms !

https://t.co/svML7f9jfL

A short & illustrated summary of this story:

[Isabel Saur @IzzySaur]

First major paper accepted from the saur lab: https://t.co/2Z2x26SYqN We demonstrate atypical AVR effector function: inhibition of the barley MLA13 NLR by the AVRa13-V2 variant. Thx to the editor and reviewers for their suggestions.
With @MerleBS4 & @Emma_Crean_

[Alan Wanke (@alanwanke.bsky.social) @alan_wanke]

The @ISMPMI meeting is coming to an end: Plenary Session 8 (chaired by @ParkerLab_MPIPZ) is kicking off with @kseniakrasileva, talking about biodiversity of plant innate immune receptors and pathogen effectors #2023ISMPMI

[Junli Wang @Junli68274596]

Great experience on the first day of #2023ISMPMI ! I will present a poster related to glutamate receptor-like channels(GLRs) promoted host cell death in ETI on Monday. Looking forward to seeing you tomorrow at P-166 in Immune Receptors II session during 12:30-13:15.

[Kathrin Wippel @kathywippel]

Join us at #2023ISMPMI Wednesday after lunch!
In addition to learning about new scientific approaches and findings, you’ll have the chance to virtually interact in the session. 📱🛜

[Maekawa lab@UniCo “Cell death & immunity” @MaekawaLab]

Please visit her talk and poster. #2023ismpmi #mlkl #concurrentsession1