Tiago Maié - phObi4.bsky.social

:)
#Bioinformatics Postdoc @vanvanka123 |
#rstats Epigenomics & ML |
@RWTH Aachen University |
🤓⌨️ |
eSports fan |
Decent home cook on a good day |
he/him

[Tiago Maié - phObi4.bsky.social @Ph0bi4]

📢 Excited to announce our latest publication: 'CimpleG: finding simple CpG methylation signatures'! 🧬🔬
@GenomeBiology 👉 https://t.co/ljZJQTuWJj & https://t.co/xjahBGj4sO
CimpleG is a framework developed by me, @Marco2Sc, Myriam Erz, @lab_wagner and @vanvanka123 1/8 🧵👇

[James Shiniti Nagai @shin_nagai]

With Bella Banjanin and Yevin Mun, it’s my pleasure to present our last hunting story. Using our joint expertise from the @vanvanka123 , @rschneiderlab , and Nombela-Arrieta Lab, we tried to find another missing piece of the complex bone marrow fibrosis puzzle.

[Mehdijoodaki @Mehdijoodakiii]

1/5) We're extending the PILOT framework! Our new PILOT-GM-VAE is now published in Briefings in Bioinformatics. It combines Gaussian Mixtures + VAEs for more powerful patient-level analysis of single-cell atlases. https://t.co/n3WLgTesf8
#SingleCellAtlas #VAE #OptimalTransport

[Costa Lab - @costalab.bsky.social @vanvanka123]

It is our pleasure to anounce DAMVISEH in Odense, DK, on Nov. 27–28, 2025. We have an exciting lineup of speakers on topics as search, clustering, and visualization in high-dimensional spaces & applications in single-cell genomics. See https://t.co/9uF6sr88gp

[Jake P. Taylor-King @wildtypehuman]

To all of the folk saying we need deep learning for RNA-seq prediction...

[Tiago Maié - phObi4.bsky.social @Ph0bi4]

In this paper, we use simulations to show that isolation-by-distance patterns in genetic diversity can persist long after habitat loss and fragmentation, revealing lasting signatures of past connectivity in fragmented species. A massive thank you to everyone involved!👏👏 (2/2)

[Tiago Maié - phObi4.bsky.social @Ph0bi4]

Check out our @PNASNews paper that was published last week: https://t.co/ZQJiuTE8W6. An amazing work by @GabiSgarlata 🔥!! With contributions from me, @ZoetenTiago, Jordi Salmona, Rita Rasteiro, and @ChikhiLounes. Very happy to see this work published! (1/2)

[Costa Lab - @costalab.bsky.social @vanvanka123]

Celebreting a busy & sucessfull #ISMBECCB2025

[Mina Shaigan - @minashaigan.bsky.social @MinaShaigan]

🔬 Ever wonder how your immune system ages?
📊 We used single-cell multi-omics (RNA + ATAC) + bulk ATAC on PBMCs to build a cell-by-cell map of aging.
🧠 Find out which genes fade, which chromatin gates close and why some immune systems age slower.
👉 Poster C-482 #ISMBECCB2025

[Costa Lab - @costalab.bsky.social @vanvanka123]

A strong tour by @GiuliaCesaro4 on cell cell Communication and intra celular signaling at ISMB

[Costa Lab - @costalab.bsky.social @vanvanka123]

Great about NicheSphere and on Myelofibrorsis PIC-seq by @mayra__ruiz_ in ISMB. Coll with @rschneiderlab

[Tiago Maié - phObi4.bsky.social @Ph0bi4]

If it quacks like a duck, if it looks like a duck, if it walks like a duck, and if it flies like a duck, then... 🤷🏾‍♂️

Follow me in blue sky:
https://t.co/u4RsxrfV5F

[Smooth Dunk @SmoothDunk]

it was a Roman Salute!

[Alan DenAdel @AlanDenadel]

Current methods in the field are trained on atlases ranging from 1 to 100 million cells. In our newest preprint, we show that these same approaches tend to plateau in performance with pre-training datasets that are only a fraction of the size.

[Costa Lab - @costalab.bsky.social @vanvanka123]

And happy to announce that SIRGURD - our approach for single cell genotyping - has now been published in its final form: https://t.co/pRQ5FCshva . New version includes tutorials on additional single cell genotyping data https://t.co/GV9F9A7YPm

[Anaïs Bardet @a_bardet]

Analyzing whole genome DNA methylation data? Our new method MethyLasso is out in NAR! It can help you identify regions with low or partial methylation (LMR, UMR, DMV, PMD, PMD) or differentially methylated regions (DMR) and was benchmarked against others
https://t.co/83dtbhDStP

[Rafeeque @rafeequemavoor]

Free scientific illustrations for biologists! 😍

@NIH has released a library of 500+ free scientific illustrations to create figures, presentations, and illustrations!

all freely available in the public domain.

Retweet and spread the message!
https://t.co/p1bD1kxO7H

[Martin Smith @martinalexsmith]

💥Cheeky 'little' update from @GencodeGenes v47, almost doubling the number of #lncRNA genes & ~4x more lncRNA transcripts. This was highlighted by @1QINGWANG when observing the greater quality of our reference-guided de novo TxOme assemblies from deep direct RNA sequencing data

[Costa Lab - @costalab.bsky.social @vanvanka123]

Thrilled to share PHLOWER, which uses Hodge Laplacians to build trajectory-level embedding for inferring complex cellular differentiation trees from multimodal (RNA+ATAC) single-cell data by @MingboCheng @jansen_jitske with @rkramann @KuppeChristoph https://t.co/1fEjq2rO0i 1/7

[Dr Richard Kirby @PlanktonPundit]

The most grim plankton compilation video I've made. This should only be a beautiful world of microlife. Instead it's a microplastic-polluted, horror movie. Beauty and the beast. @zeiss_micro

[Cristina Val-Peón @CValPeon]

Thrilled to start as PI on the EDHAVCA project at @RWTH, working with sediment samples from @cerrodelvillar_! 🌄🔬 Looking forward to new challenges and insights on vulnerable coastal areas🌊 Exciting research ahead! 💡 #StayTunned #CerroDelVillar #Research #CoastalEnvironments

[Costa Lab - @costalab.bsky.social @vanvanka123]

I am extremely happy to assume a W3 position in Computational Genomics at RWTH Aachen Medical Faculty and particularly proud to lead a diverse team (🇧🇷 🇧🇬 🇨🇳 🇬🇳 🇩🇪 🇮🇷 🇮🇹 🇯🇵 🇲🇽 🇵🇹) in advancing computational biology and genomics to discover mechanisms and therapies for diseases.