PhagesKIPRE

Phages @DrAtunga's Lab
Phages for AMR, biocontrol, decon & display
Email: [email protected].

[Huiluo Cao 曹慧荦 @hlcao]

Transposable elements are driving rapid adaptation of Enterococcus faecium | Nature https://t.co/Optyb8Bmyu

[Nicky Mulder @Nicky_Mulder]

the eLwazi metadata catalogue and harmonization tool were demonstrated at the 6th @DSI_Africa consortium meeting in Mombasa Kenya this week.

[Viruses MDPI @VirusesMDPI]

Interplay Between Bacterial Extracellular Vesicles and Phages 🦠⚔️

A closer look at how vesicles can both block and shape phage infection dynamics.

https://t.co/hDsy6KMDtX

[PhagesKIPRE @PhagesIPR]

#Review paper from the team
How can Kenya improve the diagnosis, treatment, and long‑term management of Helicobacter pylori, given rising antimicrobial resistance, limited diagnostic capacity, and the need for feasible emerging therapies?
https://t.co/13fVTcACLv
#comicAI

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

🧬 New paper: SARS‑CoV‑2 doesn’t just disrupt the microbiome: it reshapes the phageome.
@siddharthstomar & @CsirEvc share their findings showing phage richness skyrockets in infected individuals (79 vs. 28 genera), bacterial diversity drops. Read more: https://t.co/a5q4clT3ux

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

✨New paper
K. pneumoniae persists up to 24 h on hospital surfaces, with persistence at 24°C. Osorio et al. from Columbia show a 3‑phage cocktail delivers ~5‑log killing in 6 h and prevents disinfectant‑linked regrowth.
Read more here: https://t.co/9WSqeIHmUA

[Antonio J Vallecillo, PhD @Vallecillo_AJ]

Genome editing of phylogenetically distinct bacteria using cross-species retron-mediated recombineering.
https://t.co/NNcumVmAq7

[World of Science @Science_TechTV]

Bacteria has a tiny motor that makes them move- "flagellar motor"

It operates like an outboard motor, spinning a tail-like flagellum. Powered by a stream of protons, this nanomachine can rotate hundreds of times per second, enabling bacteria to swim, tumble, and navigate toward nutrients

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

New article🔎🥼
The efforts of Soviet scientist, Prof M.I. Lurie, towards phage therapy mechanisms in the 1930s.
This article would be greatly beneficial to anyone interested in the history of phage therapy and bacteriophages.
Read here:
https://t.co/RwjLQUjV7g

[Dr. Melanie Blokesch @MBlokesch]

Excited to share that our latest paper is published @ScienceMagazine
We show that HGT via natural competence drives diversification of chromosomal integrons in V. cholerae.
Thanks to Laurie, Sandrine, Loriane & Alexandre for their help with this study🥳
https://t.co/Efzmjj8MD6

[Quanta Magazine @QuantaMagazine]

The STING protein plays an essential role in immune defense across life. Its core machinery has been structurally preserved across billions of years of evolution, but its underlying gene sequences differ widely between organisms. https://t.co/dHOZhPufXE

[Kotaro Kiga @KotaroKiga]

Very excited to share our new paper! Homing endonuclease SegB drives segmental amplification of anti-defense loci, enabling phages to escape multiple bacterial defense systems.
https://t.co/fxHCmBmYoL
Big thanks to Kotaro Chihara and to the Vasili lab.

[Natalie Wolchover @nattyover]

What's especially cool is that the flagellar motor exploits the indivisibility of 5 by 2 to run on a fuel of rising entropy as protons diffuse into cells. For me as a physics and math person, this is biology at its best. https://t.co/TBAP5H3vR3

[Harry Low’s Lab @thelowlab]

Most bacteria remain uncultured and don’t grow in the lab.. to address this am excited to share EDEN - an enhanced domestication method to grow uncultured bacteria & new diversity. Using EDEN we isolate a new species active against MDR pathogens..

https://t.co/LZ9F4B2aIZ

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

New paper 🌟 from @DrPrasanthM & team on:
Revising SP6’s lysis genes uncovers holin–endolysin–spanin strategies long missed in GenBank—showing how updated phage annotations can drive the next wave of antibacterial innovation.
Find more here: https://t.co/GPfU1HDLSP

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

Pleased to see #taxMyPhage updated to reflect the ICTV Master Species List taxonomy.
More details: https://t.co/4H4rDrv2bJ
Standalone tool: https://t.co/JosCQVx2YK
Webserver: https://t.co/kB7LHeE6FC
Thanks @milja001 & @TSPKU for keeping us updated!
#phagetaxonomy

[PHAGE: Therapy, Applications, and Research @PHAGEJournal]

Our spring issue is out now!
This includes amazing content & findings such as
• A forgotten phage thinker – MI Lurie
• Challenges and solutions in Phage Therapy
• Phages as disinfectants against MDR Klebsiella.
Explore further here: https://t.co/aScdmIyzbt

[Satoshi Kawato 川戸 智 @KawatoSatoshi]

gbdraw v0.9.1 is out now on Bioconda!
Easily visualize microbial genomes and enjoy the #gbdraw web app completely offline.
📦 Install via Bioconda: https://t.co/sjtaqHXHsk
🌐 Try the online app: https://t.co/ahqoRxbDHT
#bioinformatics #genomics #microbiology #visualization

[PhagesKIPRE @PhagesIPR]

Excited to share our latest publication on the potential role of Enterobacter phages with tail fiber drug targets isolated from Kenyan urban ecosystems.
Read the exciting findings here: https://t.co/8F14pxDKhd
Work led by @MutaiIvy & @DrAtunga and the wider brilliant global team

[Global Antibiotic R&D Partnership (GARDP) @gardp_amr]

📢 New publication in @PLOS Global Public Health

Chlamydia trachomatis and Neisseria gonorrhoeae infections are curable but often asymptomatic. When left undiagnosed, they can lead to serious complications and continued transmission.

In Kenya, a multi-center prevalence study by GARDP, the @MOH_Kenya and the @DNDi found:

• Gonorrhoea prevalence was 1.0% in pregnant women and 9.4% in key populations (at higher risk for STIs)

• Chlamydia prevalence was high in both groups: 9.6% in pregnant women and 11.2% in key populations

• Younger individuals, particularly those under 20, carried the highest burden

With STI care being largely syndromic, strengthening diagnostics 🧪 and surveillance will be critical to protect reproductive health and support antimicrobial stewardship 💊

🔗 Read the full paper: https://t.co/hXloaLCfu2

#STIs #GlobalHealth #AMR #PublicHealth